Clinical Research Nurse - Core-Center for Research Excel

Registered NurseFull-Time

Compensation

Pay not listed

The week · per this posting · weekdays assumed

Ask the employer about the pay range, the work setting, call expectations and time off.

Posted 1h ago · Verified live

Job Description

The Clinical Research Nurse (CRN) is a licensed registered nurse who supports the safe and compliant conduct of clinical research studies by integrating nursing practice with clinical trial requirements.

In collaboration with Principal Investigators, study coordinators, and interdisciplinary care teams, the CRN provides protocol-driven participant care, education, and ongoing assessment; coordinates study-related clinical activities; and ensures accurate documentation in accordance with Good Clinical Practice (GCP), institutional policies, and applicable regulations.

The CRN serves as a key liaison among participants, providers, and sponsors/CROs to promote participant safety, data integrity, and an excellent research participant experience. The CRN is responsible for performing job duties in accordance with the mission, vision, and values of Tampa General Hospital.

Education Qualifications

Nursing

Experience Qualifications

A minimum of two (2) yrs of bedside nursing required.

Key Responsibilities

The Clinical Research Nurse supports the safe and compliant conduct of clinical research by integrating nursing practice with trial protocols. They act as a liaison between participants, investigators, and sponsors to ensure data integrity and high-quality participant care.

Requirements

Candidates must be licensed registered nurses with a minimum of two years of bedside nursing experience. Proficiency in Good Clinical Practice and institutional regulatory standards is required.

Qualifications

Education
Professional certificate or licensure
Experience
2+ years of experience

Key Skills

Patient CareProtocol ComplianceClinical TrialsParticipant AssessmentInterdisciplinary CollaborationRegulatory CompliancePatient Education

Ambulatory Care Nursing — Registered Nurse Career Context

Of the 50 active Ambulatory Care Nursing listings this role was benchmarked against, 24% are remote, 48% have no call, 78% require no weekends.

In Florida, the Ambulatory Care Nursing weighted monthly median benchmark on WeekdayDoc is ~$90k (13 salary observations; 66 listings), vs ~$96k nationally (400 salary observations; 1,262 listings). Monthly aggregates cover 2026-01-01 through 2026-10-01; these are not the modal's selected comparable-job medians.

The cost-of-living index for Florida is 103.4 (US average = 100; BEA Regional Price Parities (2024)). 58.1% of Florida clinicians report burnout symptoms in WeekdayDoc's Burnout Index (2026-01 data).

Ambulatory Care Nursing pay on WeekdayDoc is down 1.1% vs. the prior quarter (through Sep 2026).

Location & Logistics

Florida has no state income tax, which can significantly increase take-home pay compared to high-tax states.

Top Registered Nurse Jobs

38 matches · ranked by pay

Salary Distribution35 jobs · 34 employers

11
<$95k
7
$95k-115k
11
$115k-135k
4
$135k-155k
2
$155k+

Annual compensation range

Benefits & Perks30 jobs

401k / retirement match
90%
Loan repayment
17%
CME allowance
17%
PSLF eligible
17%
Sign-on bonus
3%

Share of similar jobs offering each benefit

#1

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Providence · Tukwila, Washington

$52.26-$81.13/hr
#2

Director of Nursing DON - Acute Inpatient Mental Health 264

Telecare · Shelton, Washington

$144k-$165k
#3

Registered Nurse (RN) Patient Care Navigator - Transplant Infectious Diseases

$93k-$151k
#4

Asst. Director of Nursing - Ambulatory Care - Newkirk Avenue

$136,708 - $150,000
+ 36 more · ranked by pay

Work-life snapshot

median 5.1this job 3.0
Better work-life than 20% of Ambulatory Care Nursing (RN) listings

Listing-based score, 0–10, across 389 comparable listings. Shaded area = the share scoring below this one.

Living in Tampa

Typical 3-bedroom home value
$384k
Typical market rent
$1,957/mo
Residents’ average commute
25 min
Metro price indexU.S. average = 100
100.9
State income tax
None
Sources & methodology

Sources: Zillow home values (Aug 2026), Zillow market rents (Aug 2026), U.S. Census ACS 2024 five-year.

BEA 2024 · Tampa-St. Petersburg-Clearwater, FL metro prices. Housing figures are city-level.

City-level figures. Not a cost-of-living guarantee.