Registered Nurse Jobs in South Carolina
Registered Nurse Jobs in South Carolina with pay where disclosed, schedule details, and work-life-balance signals. Compare each listing's currency, pay period, location, and requirements before applying.
111+ positions available
111+ Registered Nurse Jobs in South Carolina Available Now
These 24 roles pay ~$95k median with 4.5/10 median work-life balance — use these as your benchmarks.
Salary Distribution24 jobs · 14 employers
Annual compensation range
Work-Life Balance Distribution24 jobs · 14 employers
Higher = better work-life balance
Registered Nurse (RN) - Case Manager
Angels of Care Pediatric Home HealthColumbia, SC
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How South Carolina Compares for Registered Nurse Pay
South Carolina against neighboring states and the top payers, from our own registered nurse postings over the last 12 months — not a salary survey.
Registered Nurse roles in South Carolina advertise $5k below the $92k median across the 51 states we can measure, where Hawaii leads at $121k.
| State | Median pay | vs SC | WLB | Listings |
|---|---|---|---|---|
| South Carolina (this page) | $87k | — | 4.1/10 | 458 |
| Hawaii#1 | $121k | +$34k | 4.1/10 | 44 |
| California#2 | $119k | +$32k | 4.5/10 | 1057 |
| Washington#3 | $114k | +$27k | 4.4/10 | 295 |
| Alaska#4 | $112k | +$25k | 4.8/10 | 46 |
| Oregon#5 | $112k | +$25k | 4.5/10 | 140 |
| Georgiaborders | $89k | +$2k | 4.3/10 | 892 |
| North Carolinaborders | $82k | −$5k | 4.8/10 | 729 |
“borders” = shares a border with South Carolina; “#n” = national pay rank among the 51 measured states.
Registered Nurse Jobs in South Carolina: Market Overview & Work-Life Balance
Listing snapshot: this overview summarizes the jobs loaded on this page. Market comparisons use the separate scope and time period labeled in their section.
South Carolina offers a competitive market for healthcare professionals seeking registered nurse jobs in south carolina. With 111+ open positions, clinicians have strong options for career growth and work-life balance.
Every listing is evaluated using WeekdayDoc's proprietary work-life balance scoring system. Registered Nurse Jobs in South Carolina on this page have an average score of 2.6/10, with 10% offering remote work. This data helps clinicians quickly identify positions that match their lifestyle priorities without reading through hundreds of job descriptions.
Leading employers currently hiring for registered nurse jobs in south carolina include McLeod Health, Pruitt Health, MUSC, Piedmont Healthcare, and more. Positions span registered nurse jobs south carolina. New jobs are added daily as healthcare organizations expand their teams.
Among the top-rated employers hiring for registered nurse jobs in south carolina, Talkiatry (score: 95.1/100), BetterHelp (score: 94.9/100), Hiaah (score: 94.5/100) have earned WeekdayDoc's Top Employer designation based on our proprietary ranking system. This ranking evaluates burnout scores (40%), salary competitiveness (30%), and work-life balance features like no-call and remote options (30%). See the full rankings on our Top Employers page.
According to WeekdayDoc's Market Pulse — which tracks real-time compensation data from thousands of active job postings — the current median salary is $104K, trending up 3.4% over the past quarter. This data is derived from 21,713+ job postings analyzed over the past 12 months — updated daily, unlike annual survey-based reports. Explore salary trends and burnout data on our Market Pulse dashboard.
A few things worth knowing
About Registered Nurse jobs in South Carolina.
How much do registered nurses earn in South Carolina?
A reliable salary estimate is unavailable for this sample of registered nurses. Compensation varies by role, specialty, location, and schedule. Compare employer-posted pay where disclosed, including its currency and pay period; missing pay is not estimated.
Are there remote or hybrid registered nurses jobs available?
Yes — about 10% of current registered nurses listings offer remote or hybrid work. You can filter for telehealth and work-from-home options, and every listing shows its remote status before you apply.
Which registered nurses jobs have the best work-life balance?
Every registered nurse role on WeekdayDoc is scored for burnout risk using call schedule, weekend and night requirements, and remote flexibility. You can sort by work-life-balance score to surface the lowest-burnout roles first.
Who is hiring registered nurses in South Carolina right now?
Employers currently hiring for registered nurse roles include McLeod Health, Pruitt Health, MUSC, Piedmont Healthcare, and others. WeekdayDoc aggregates verified openings from these and other organizations, refreshed daily.
How many registered nurse jobs in south carolina are available, and how often are they updated?
There are currently 111 registered nurses positions in South Carolina listed, with new roles added as employers post them. Job descriptions are public. Verified sign-in with Google or email gives free access to regular Apply, full search, and standard Market Insights. Saved jobs, My Search, and the dashboard also require verified sign-in. Eligible featured employer listings allow Apply without signup or email. Basic calculators are public and free; optional AI contract analysis, RVU Billing Optimizer, and Schedule Optimizer reports remain paid.
Employers hiring now
Organizations with the most openings in Registered Nurse Jobs in South Carolina
MUSC11 open roles here · WLB 54/100
Prisma Health11 open roles here · WLB 50/100
Pruitt Health11 open roles here · WLB 73/100
McLeod Health9 open roles here · WLB 75/100
Crescent Hospice4 open roles here · WLB 57/100CVS Health4 open roles here · WLB 61/100
Unifi Healthcare4 open roles here · WLB 73/100Amedisys3 open roles here · WLB 64/100