Location

22+ Registered Nurse Jobs in South Dakota

Registered Nurse positions in South Dakota with $65K-$100K salary ranges, burnout scores, and schedule details shown upfront. Filter by no call, remote, and weekday-only.

22+ positions available

22+ Registered Nurse Jobs in South Dakota Available Now

These 20 roles pay ~$90k median with 6.4/10 median work-life balance — use these as your benchmarks.

Monument Health logo

Registered Nurse Patient Navigator | Cardiology Clinic

Monument Health

Registered NurseRapid City, SD
32-$40 per hour
4d ago
Monument Health logo

Cardiothoracic/Vascular Surgery Nurse Navigator

Monument Health

Registered NurseRapid City, SD
32-$40 per hour
4d ago
Peaceful Pines Senior Living - Mitchell logo

Director of Nursing

Peaceful Pines Senior Living - Mitchell

Vibra Healthcare logo

Chief Nursing Officer CNO

Vibra Healthcare

Monument Health logo

Registered Nurse Patient Navigator | Cancer Care Institute

Monument Health

Registered NurseRapid City, SD
32-$40 per hour
2w ago
Top 25%

in Oncology (RN)

Interim HealthCare of the Black Hills logo

Registered Nurse Case Manager (RN)

Interim HealthCare of the Black Hills

Top 25%

in Nurse Case Manager

SAGE GROUP logo

Director of Nursing – Long-Term Care

Sage Group

Registered NurseMiller, SD
38-$63 per hour
3w ago
Top 10%

in Nursing Leadership

Avera Health logo

Clinical Nurse Educator (RN) | Long Term Care

Avera Health

Registered NurseAberdeen, SD
34.5-$48.5 per hour
3w ago
Avera Health logo

Assistant Director of Nursing | Maryhouse Long Term Care

Avera Health

Sanford Health logo

PRN RN Case Manager, Home Health

Sanford Health

Monument Health logo

Registered Nurse Patient Navigator

Monument Health

Registered NurseRapid City, SD
66k - $83k
30+ days ago
Top 25%

in Registered Nurse roles

Peaceful Pines Senior Living - Mitchell logo

Assistant Director of Nursing

Peaceful Pines Senior Living - Mitchell

Avera Health logo

Nurse Manager | Behavioral Health | Child and Addiction Adolescent Units

Avera Health

Avera Health logo

Registered Nurse (RN) Case Manager | Family Med Clinic

Avera Health

Registered NurseYankton, SD
27.75-$41.25 per hour
2d ago
No NightsNo Weekends
Above avg

in Nurse Case Manager

Avera Health logo

Registered Nurse (RN) | Navigator

Avera Health

Registered NurseSioux Falls, SD
29-$43.25 per hour
5d ago
No Nights

A registered nurse in south dakota role paying $38-$63/hr is hidden in this list.

21 more hidden below, ranked by pay and work-life.

Your Registered Nurse in South Dakota DashboardUpdated daily
#1 Match
6.6/10

Director of Nursing – Long-Term Care

Miller, South Dakota38-$63/hr
Sign-on bonus
+ 21 more · up to $38-$63/hr

Negotiation brief with every application

Your counter number + word-for-word script

90-day pass — $57One-time · 90 days · no subscription, no auto-renew

One-time payment · dashboard + negotiation brief on every application

4 more roles in this search — preview locked listings

How South Dakota Compares for Registered Nurse Pay

South Dakota against neighboring states and the top payers, from our own registered nurse postings over the last 12 months — not a salary survey.

Median advertised
$101k
Pay rank
#16 of 51
Work-life balance
5.3/10 · #3
Open listings
25

Registered Nurse roles in South Dakota advertise $3k above the $98k median across the 51 states we can measure, where West Virginia leads at $129k.

Registered Nurse median pay and work-life-balance score, South Dakota compared with neighboring states and the highest-paying states
StateMedian payvs SDWLBListings
South Dakota (this page)$101k5.3/1025
West Virginia#1$129k+$27k5.0/1060
Wyomingborders$105k+$4k4.4/109
Montanaborders$95k−$6k4.0/1032
North Dakotaborders$92k−$9k4.1/1025
Nebraskaborders$91k−$10k4.8/1030
Minnesotaborders$91k−$11k4.5/10163
Iowaborders$75k−$26k4.9/10104

“borders” = shares a border with South Dakota; “#n” = national pay rank among the 51 measured states.

Registered Nurse Jobs in South Dakota: Salary, Outlook & Work-Life Balance

South Dakota offers a competitive market for healthcare professionals seeking registered nurse jobs in south dakota. With 22+ open positions and salaries ranging from $32K to $131K, clinicians have strong options for career growth and work-life balance.

Every listing is evaluated using WeekdayDoc's proprietary work-life balance scoring system. Registered Nurse Jobs in South Dakota on this page have an average score of 4.3/10, with 5% with no on-call requirements, 15% with no weekends. This data helps clinicians quickly identify positions that match their lifestyle priorities without reading through hundreds of job descriptions.

Leading employers currently hiring for registered nurse jobs in south dakota include Avera Health, Monument Health, Peaceful Pines Senior Living - Mitchell, Sanford Health, and more. Positions span registered nurse jobs south dakota. New jobs are added daily as healthcare organizations expand their teams.

Among the top-rated employers hiring for registered nurse jobs in south dakota, Talkiatry (score: 95.8/100), Up Lift (score: 94.5/100), Cyti Clinics (score: 94.5/100) have earned WeekdayDoc's Top Employer designation based on our proprietary ranking system. This ranking evaluates burnout scores (40%), salary competitiveness (30%), and work-life balance features like no-call and remote options (30%). See the full rankings on our Top Employers page.

According to WeekdayDoc's Market Pulse — which tracks real-time compensation data from thousands of active job postings — the current median salary is $101K, trending down 4.9% over the past quarter. This data is derived from 7,451+ job postings analyzed over the past 12 months — updated daily, unlike annual survey-based reports. Explore salary trends and burnout data on our Market Pulse dashboard.

Frequently Asked Questions

How much do registered nurses earn in South Dakota?

Listed registered nurses in South Dakota on WeekdayDoc pay roughly $32K to $131K per year, with a median near $67K. Actual pay varies by specialty, setting, experience, and shift type — every listing shows its salary upfront.

Are there remote or hybrid registered nurses jobs available?

Some registered nurses roles offer remote or hybrid flexibility. You can filter for telehealth and work-from-home options, and every listing shows its remote status before you apply.

Which registered nurses jobs have the best work-life balance?

Every registered nurse role on WeekdayDoc is scored for burnout risk using call schedule, weekend and night requirements, and remote flexibility. Among current listings, 5% with no on-call and 15% with no weekends. You can sort by work-life-balance score to surface the lowest-burnout roles first.

Who is hiring registered nurses in South Dakota right now?

Employers currently hiring for registered nurse roles include Avera Health, Monument Health, Peaceful Pines Senior Living - Mitchell, Sanford Health, and others. WeekdayDoc aggregates verified openings from these and other organizations, refreshed daily.

How many registered nurse jobs in south dakota are available, and how often are they updated?

There are currently 22+ registered nurses positions in South Dakota listed, with new roles added daily as employers post them. Create a free account to compare salaries and work-life-balance scores side by side, then apply directly.

Never miss a role

Get New Healthcare Jobs Emailed to You

Drop your email and we'll send you new registered nurse jobs in south dakota as they're posted — each one with salary data and a burnout score. Free, no spam.

Free · No spam · Unsubscribe anytime