Nurse Practitioner Jobs in South Carolina
Nurse Practitioner Jobs in South Carolina with pay where disclosed, schedule details, and work-life-balance signals. Compare each listing's currency, pay period, location, and requirements before applying.
300+ positions available
300+ Nurse Practitioner Jobs in South Carolina Available Now
These 80 roles pay ~$162k median with 6.5/10 median work-life balance — use these as your benchmarks.
Salary Distribution80 jobs · 29 employers
Annual compensation range
Work-Life Balance Distribution80 jobs · 29 employers
Higher = better work-life balance
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How South Carolina Compares for Nurse Practitioner Pay
South Carolina against neighboring states and the top payers, from our own nurse practitioner postings over the last 12 months — not a salary survey.
Nurse Practitioner roles in South Carolina advertise $5k below the $136k median across the 51 states we can measure, where Rhode Island leads at $164k.
| State | Median pay | vs SC | WLB | Listings |
|---|---|---|---|---|
| South Carolina (this page) | $131k | — | 5.2/10 | 950 |
| Rhode Island#1 | $164k | +$33k | 5.3/10 | 192 |
| California#2 | $163k | +$32k | 5.3/10 | 2969 |
| Alaska#3 | $154k | +$23k | 5.2/10 | 87 |
| Washington#4 | $153k | +$22k | 5.5/10 | 842 |
| North Dakota#5 | $152k | +$21k | 6.2/10 | 54 |
| Georgiaborders | $131k | +$0k | 5.0/10 | 1227 |
| North Carolinaborders | $130k | −$1k | 5.4/10 | 1139 |
“borders” = shares a border with South Carolina; “#n” = national pay rank among the 51 measured states.
Nurse Practitioner Jobs in South Carolina: Market Overview & Work-Life Balance
Listing snapshot: this overview summarizes the jobs loaded on this page. Market comparisons use the separate scope and time period labeled in their section.
South Carolina offers a competitive market for healthcare professionals seeking nurse practitioner jobs in south carolina. With 300+ open positions, clinicians have strong options for career growth and work-life balance.
Every listing is evaluated using WeekdayDoc's proprietary work-life balance scoring system. Nurse Practitioner Jobs in South Carolina on this page have an average score of 2.3/10. This data helps clinicians quickly identify positions that match their lifestyle priorities without reading through hundreds of job descriptions.
Leading employers currently hiring for nurse practitioner jobs in south carolina include Prisma Health, Agape Care Group, Pruitt Health, Curana Health, and more. Positions span nurse practitioner jobs south carolina. New jobs are added daily as healthcare organizations expand their teams.
Among the top-rated employers hiring for nurse practitioner jobs in south carolina, Talkiatry (score: 95.1/100), BetterHelp (score: 94.9/100), Hiaah (score: 94.5/100) have earned WeekdayDoc's Top Employer designation based on our proprietary ranking system. This ranking evaluates burnout scores (40%), salary competitiveness (30%), and work-life balance features like no-call and remote options (30%). See the full rankings on our Top Employers page.
According to WeekdayDoc's Market Pulse — which tracks real-time compensation data from thousands of active job postings — the current median salary is $104K, trending up 3.4% over the past quarter. This data is derived from 21,713+ job postings analyzed over the past 12 months — updated daily, unlike annual survey-based reports. Explore salary trends and burnout data on our Market Pulse dashboard.
A few things worth knowing
About Nurse Practitioner jobs in South Carolina.
How much do nurse practitioners earn in South Carolina?
A reliable salary estimate is unavailable for this sample of nurse practitioners. Compensation varies by role, specialty, location, and schedule. Compare employer-posted pay where disclosed, including its currency and pay period; missing pay is not estimated.
Are there remote or hybrid nurse practitioners jobs available?
Some nurse practitioners roles offer remote or hybrid flexibility. You can filter for telehealth and work-from-home options, and every listing shows its remote status before you apply.
Which nurse practitioners jobs have the best work-life balance?
Every nurse practitioner role on WeekdayDoc is scored for burnout risk using call schedule, weekend and night requirements, and remote flexibility. You can sort by work-life-balance score to surface the lowest-burnout roles first.
Who is hiring nurse practitioners in South Carolina right now?
Employers currently hiring for nurse practitioner roles include Prisma Health, Agape Care Group, Pruitt Health, Curana Health, and others. WeekdayDoc aggregates verified openings from these and other organizations, refreshed daily.
How many nurse practitioner jobs in south carolina are available, and how often are they updated?
There are currently 300 nurse practitioners positions in South Carolina listed, with new roles added as employers post them. Job descriptions are public. Verified sign-in with Google or email gives free access to regular Apply, full search, and standard Market Insights. Saved jobs, My Search, and the dashboard also require verified sign-in. Eligible featured employer listings allow Apply without signup or email. Basic calculators are public and free; optional AI contract analysis, RVU Billing Optimizer, and Schedule Optimizer reports remain paid.
Employers hiring now
Organizations with the most openings in Nurse Practitioner Jobs in South Carolina
MUSC37 open roles here · WLB 54/100
Prisma Health36 open roles here · WLB 50/100
Prisma Health Urgent Care17 open roles here · WLB 74/100
Curana Health16 open roles here · WLB 64/100
Lexington Medical Center16 open roles here · WLB 46/100
Matrix Medical Network15 open roles here · WLB 74/100
Self Regional Healthcare12 open roles here · WLB 66/100
Pruitt Health11 open roles here · WLB 73/100