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Remote Nurse Practitioner Jobs in South Carolina

Across 29 live Remote Nurse Practitioner listings in South Carolina, median advertised pay is $190K, based on the 11 that state a salary; South Carolina ranks 36th of 51 states by median advertised pay; the employers with the most openings are WellStreet Urgent Care (9), LifeStance Health (5), Prisma Health Urgent Care (5).

29+ positions available

Figures are computed from live listings and reviewed by WeekdayDoc’s physician-led editorial team; data as of October 16, 2026. Posted ranges, not accepted offers. How we compute this

29+ Remote Nurse Practitioner Jobs in South Carolina Available Now

Prioritize:

29 jobs

These 11 roles pay ~$190k median with 8.1/10 median work-life balance — use these as your benchmarks.

Salary Distribution11 jobs · 6 employers

2
$94k
1
$130k
1
$140k
1
$166k
6
$190k+

Annual compensation range

Work-Life Balance Distribution11 jobs · 6 employers

0
1-2
0
3-4
0
5-6
5
7-8
6
9-10

Higher = better work-life balance

Prisma Health Urgent Care logo

Urgent Care Physician - Remote APP Supervision

Prisma Health Urgent CareRemote

Nurse Practitioner
Pay not disclosed
3d ago
WellStreet Urgent Care logo

Urgent Care Physician - Remote APP Supervision

WellStreet Urgent CareRemote

Nurse Practitioner
Pay not disclosed
3d ago
WellStreet Urgent Care logo

Urgent Care Physician - Remote APP Supervision

WellStreet Urgent CareRemote

Nurse Practitioner
Pay not disclosed
3d ago
WellStreet Urgent Care logo

Urgent Care Physician - Remote APP Supervision

WellStreet Urgent CareRemote

Nurse Practitioner
Pay not disclosed
3d ago
WellStreet Urgent Care logo

Urgent Care Physician - Remote APP Supervision

WellStreet Urgent CareRemote

Nurse Practitioner
Pay not disclosed
3d ago
Prisma Health Urgent Care logo

Urgent Care Physician - Remote APP Supervision

Prisma Health Urgent CareRemote

Nurse Practitioner
Pay not disclosed
3d ago
WellStreet Urgent Care logo

Urgent Care Physician - Remote APP Supervision

WellStreet Urgent CareRemote

Nurse Practitioner
Pay not disclosed
3d ago
WellStreet Urgent Care logo

Urgent Care Physician - Remote APP Supervising

WellStreet Urgent CareRemote

Nurse Practitioner
Pay not disclosed
5d ago
Prisma Health Urgent Care logo

Urgent Care Physician - Remote APP Supervising

Prisma Health Urgent CareRemote

Nurse Practitioner
Pay not disclosed
5d ago
Prisma Health Urgent Care logo

Urgent Care Physician - Remote APP Supervising

Prisma Health Urgent CareRemote

Nurse Practitioner
Pay not disclosed
6d ago
WellStreet Urgent Care logo

Urgent Care Physician - Remote APP Supervising

WellStreet Urgent CareRemote

Nurse Practitioner
Pay not disclosed
6d ago
Sonder Mind logo

Psychiatric Nurse Practitioner

Sonder MindEmployer score · GoldRemote

Nurse Practitioner
$200 per hour
30+ days ago
Sprinter Health logo

Virtual Family Nurse Practitioner (SC License Required) | 3-Week Paid Sabbatical in Q1

Sprinter HealthEmployer score · SilverRemote

Nurse Practitioner
$120,000 - $130,000
MUSC logo

Nurse Practitioner or Physician Assistant - Primary Care Float

MUSCSouth Carolina

Nurse Practitioner
Pay not disclosed
Hybrid
MUSC logo

Virtual PRN Advanced Practice Provider (NP/PA) | MUSC Health Department of Emergency Medicine | Telehealth

MUSCRemote

Nurse Practitioner
Pay not disclosed

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How South Carolina Compares for Nurse Practitioner Pay

South Carolina against neighboring states and the top payers, from our own nurse practitioner postings over the last 12 months — not a salary survey.

Median advertised
$132k
Pay rank
#36 of 51
Work-life balance
5.3/10 · #32
Open listings
927

Nurse Practitioner roles in South Carolina advertise $3k below the $135k median across the 51 states we can measure, where California leads at $163k.

Nurse Practitioner median pay and work-life-balance score, South Carolina compared with neighboring states and the highest-paying states
StateMedian payvs SCWLBListings
South Carolina (this page)$132k—5.3/10927
California#1$163k+$31k5.3/103098
Washington#2$153k+$21k5.5/10900
Oregon#3$152k+$20k6.0/10660
Alaska#4$152k+$20k5.3/1078
Rhode Island#5$151k+$20k5.5/10182
Georgiaborders$133k+$1k5.1/101231
North Carolinaborders$130k−$2k5.4/101181

“borders” = shares a border with South Carolina; “#n” = national pay rank among the 51 measured states.

Remote Nurse Practitioner Jobs in South Carolina: Market Overview & Work-Life Balance

Listing snapshot: this overview summarizes the jobs loaded on this page. Market comparisons use the separate scope and time period labeled in their section.

South Carolina offers a competitive market for healthcare professionals seeking remote nurse practitioner jobs in south carolina. With 29+ open positions, clinicians have strong options for career growth and work-life balance. 100% of listed positions offer remote or hybrid arrangements.

Every listing is evaluated using WeekdayDoc's proprietary work-life balance scoring system. Remote Nurse Practitioner Jobs in South Carolina on this page have an average score of 5.6/10, with 15% with no on-call requirements, 10% with no weekends, 100% offering remote work. This data helps clinicians quickly identify positions that match their lifestyle priorities without reading through hundreds of job descriptions.

Leading employers currently hiring for remote nurse practitioner jobs in south carolina include WellStreet Urgent Care, Prisma Health Urgent Care, MUSC, Sonder Mind, and more. Positions span remote nurse practitioner jobs south carolina. New jobs are added daily as healthcare organizations expand their teams.

Among the top-rated employers hiring for remote nurse practitioner jobs in south carolina, BetterHelp (score: 95.9/100), Talkiatry (score: 95.0/100), Hiaah (score: 94.5/100) have earned WeekdayDoc's Top Employer designation based on our proprietary ranking system. This ranking evaluates burnout scores (40%), salary competitiveness (30%), and work-life balance features like no-call and remote options (30%). See the full rankings on our Top Employers page.

According to WeekdayDoc's Market Pulse — which tracks real-time compensation data from thousands of active job postings — the current median salary is $105K, trending up 3.4% over the past quarter. This data is derived from 38,293+ job postings analyzed over the past 12 months — updated daily, unlike annual survey-based reports. Explore salary trends and burnout data on our Market Pulse dashboard.

A few things worth knowing

About Remote Nurse Practitioner jobs in South Carolina.

How much do nurse practitioners earn in South Carolina?

A reliable salary estimate is unavailable for this sample of nurse practitioners. Compensation varies by role, specialty, location, and schedule. Compare employer-posted pay where disclosed, including its currency and pay period; missing pay is not estimated.

Are nurse practitioners jobs fully remote?

100% of the nurse practitioners roles on this page are remote or hybrid. These include telehealth, chart review, case management, and utilization-review positions you can do from home. Each listing states whether it's fully remote, hybrid, or occasionally on-site.

Which nurse practitioners jobs have the best work-life balance?

Every nurse practitioner role on WeekdayDoc is scored for burnout risk using call schedule, weekend and night requirements, and remote flexibility. Among current listings, 15% with no on-call and 10% with no weekends. You can sort by work-life-balance score to surface the lowest-burnout roles first.

Who is hiring nurse practitioners in South Carolina right now?

Employers currently hiring for nurse practitioner roles include WellStreet Urgent Care, Prisma Health Urgent Care, MUSC, Sonder Mind, and others. WeekdayDoc aggregates verified openings from these and other organizations, refreshed daily.

How many remote nurse practitioner jobs in south carolina are available, and how often are they updated?

There are currently 29 nurse practitioners positions in South Carolina listed, with new roles added as employers post them. Job descriptions are public. Verified sign-in with Google or email gives free access to regular Apply, full search, and standard Market Insights. Saved jobs, My Search, and the dashboard also require verified sign-in. Eligible featured employer listings allow Apply without signup or email. Basic calculators are public and free; optional AI contract analysis, RVU Billing Optimizer, and Schedule Optimizer reports remain paid.