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Remote Nurse Practitioner Jobs in South Carolina

Across 29 live Remote Nurse Practitioner listings in South Carolina, median advertised pay is $190K, based on the 11 that state a salary; South Carolina ranks 36th of 51 states by median advertised pay; the employers with the most openings are WellStreet Urgent Care (9), LifeStance Health (5), Prisma Health Urgent Care (5).

29+ positions available

Figures are computed from live listings and reviewed by WeekdayDoc’s physician-led editorial team; data as of October 16, 2026. Posted ranges, not accepted offers. How we compute this

29+ Remote Nurse Practitioner Jobs in South Carolina Available Now

Prioritize:

29 jobs

These 11 roles pay ~$190k median with 8.1/10 median work-life balance — use these as your benchmarks.

LifeStance Health logo

Psychiatric Nurse Practitioner (PMHNP) - Child/Adolescent

LifeStance HealthEmployer score · SilverForest Acres, SC

Nurse Practitioner
$142,000-$190,000
2w ago
HybridNo Weekends
LifeStance Health logo

Psychiatric Nurse Practitioner (PMHNP) - Child/Adolescent

LifeStance HealthEmployer score · SilverCayce, SC

Nurse Practitioner
$142,000-$190,000
2w ago
HybridNo Weekends
Devoted Medical Group logo

Telehealth Preventative Primary Care Advanced Practice Provider- NP/PA

Devoted Medical GroupEmployer score · SilverRemote

Nurse Practitioner
$115,000-$140,000
3w ago
No Call
LifeStance Health logo

Psychiatric Nurse Practitioner (PMHNP) - Outpatient and Spravato

LifeStance HealthEmployer score · SilverForest Acres, SC

Nurse Practitioner
$142,000-$190,000
3w ago
HybridNo Weekends
LifeStance Health logo

Psychiatric Nurse Practitioner (PMHNP) - Child/Adolescent/Adult

LifeStance HealthEmployer score · SilverCayce, SC

Nurse Practitioner
$142,000-$190,000
30+ days ago
HybridNo Weekends
Thriveworks logo

Weekends and Evenings Remote Nurse Practitioner - Fee For Service

ThriveworksEmployer score · SilverRemote

Nurse Practitioner
$65,000-$94,000
30+ days ago
No Call
Thriveworks logo

Part Time Remote Psychiatric Nurse Practitioner - Fee For Service

ThriveworksEmployer score · SilverRemote

Nurse Practitioner
$65,000-$94,000
30+ days ago
No Call
Trusted Results Therapy Group logo

Psychiatric Mental Health Nurse Practitioner(PMHNP)

Trusted Results Therapy GroupEmployer score · SilverRemote

Nurse Practitioner
Pay not disclosed
No Weekends
MUSC logo

Nurse Practitioner or Physician Assistant - First Assist Outpatient - Neurosurgery

MUSCRemote

Nurse Practitioner
$250 per hour
No Weekends

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How South Carolina Compares for Nurse Practitioner Pay

South Carolina against neighboring states and the top payers, from our own nurse practitioner postings over the last 12 months — not a salary survey.

Median advertised
$132k
Pay rank
#36 of 51
Work-life balance
5.3/10 · #32
Open listings
927

Nurse Practitioner roles in South Carolina advertise $3k below the $135k median across the 51 states we can measure, where California leads at $163k.

Nurse Practitioner median pay and work-life-balance score, South Carolina compared with neighboring states and the highest-paying states
StateMedian payvs SCWLBListings
South Carolina (this page)$132k—5.3/10927
California#1$163k+$31k5.3/103098
Washington#2$153k+$21k5.5/10900
Oregon#3$152k+$20k6.0/10660
Alaska#4$152k+$20k5.3/1078
Rhode Island#5$151k+$20k5.5/10182
Georgiaborders$133k+$1k5.1/101231
North Carolinaborders$130k−$2k5.4/101181

“borders” = shares a border with South Carolina; “#n” = national pay rank among the 51 measured states.

Remote Nurse Practitioner Jobs in South Carolina: Market Overview & Work-Life Balance

Listing snapshot: this overview summarizes the jobs loaded on this page. Market comparisons use the separate scope and time period labeled in their section.

South Carolina offers a competitive market for healthcare professionals seeking remote nurse practitioner jobs in south carolina. With 29+ open positions, clinicians have strong options for career growth and work-life balance. 100% of listed positions offer remote or hybrid arrangements.

Every listing is evaluated using WeekdayDoc's proprietary work-life balance scoring system. Remote Nurse Practitioner Jobs in South Carolina on this page have an average score of 7.3/10, with 33% with no on-call requirements, 67% with no weekends, 100% offering remote work. This data helps clinicians quickly identify positions that match their lifestyle priorities without reading through hundreds of job descriptions.

Leading employers currently hiring for remote nurse practitioner jobs in south carolina include LifeStance Health, Thriveworks, Devoted Medical Group, Trusted Results Therapy Group, and more. Positions span remote nurse practitioner jobs south carolina. New jobs are added daily as healthcare organizations expand their teams.

Among the top-rated employers hiring for remote nurse practitioner jobs in south carolina, BetterHelp (score: 95.9/100), Talkiatry (score: 95.0/100), Hiaah (score: 94.5/100) have earned WeekdayDoc's Top Employer designation based on our proprietary ranking system. This ranking evaluates burnout scores (40%), salary competitiveness (30%), and work-life balance features like no-call and remote options (30%). See the full rankings on our Top Employers page.

According to WeekdayDoc's Market Pulse — which tracks real-time compensation data from thousands of active job postings — the current median salary is $105K, trending up 3.4% over the past quarter. This data is derived from 38,654+ job postings analyzed over the past 12 months — updated daily, unlike annual survey-based reports. Explore salary trends and burnout data on our Market Pulse dashboard.

A few things worth knowing

About Remote Nurse Practitioner jobs in South Carolina.

How much do nurse practitioners earn in South Carolina?

A reliable salary estimate is unavailable for this sample of nurse practitioners. Compensation varies by role, specialty, location, and schedule. Compare employer-posted pay where disclosed, including its currency and pay period; missing pay is not estimated.

Are nurse practitioners jobs fully remote?

100% of the nurse practitioners roles on this page are remote or hybrid. These include telehealth, chart review, case management, and utilization-review positions you can do from home. Each listing states whether it's fully remote, hybrid, or occasionally on-site.

Which nurse practitioners jobs have the best work-life balance?

Every nurse practitioner role on WeekdayDoc is scored for burnout risk using call schedule, weekend and night requirements, and remote flexibility. Among current listings, 33% with no on-call and 67% with no weekends. You can sort by work-life-balance score to surface the lowest-burnout roles first.

Who is hiring nurse practitioners in South Carolina right now?

Employers currently hiring for nurse practitioner roles include LifeStance Health, Thriveworks, Devoted Medical Group, Trusted Results Therapy Group, and others. WeekdayDoc aggregates verified openings from these and other organizations, refreshed daily.

How many remote nurse practitioner jobs in south carolina are available, and how often are they updated?

There are currently 29 nurse practitioners positions in South Carolina listed, with new roles added as employers post them. Job descriptions are public. Verified sign-in with Google or email gives free access to regular Apply, full search, and standard Market Insights. Saved jobs, My Search, and the dashboard also require verified sign-in. Eligible featured employer listings allow Apply without signup or email. Basic calculators are public and free; optional AI contract analysis, RVU Billing Optimizer, and Schedule Optimizer reports remain paid.