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Mayo Clinic
Minnesota

Acute Care Nurse Practitioner or Physician Assistant - Hematology / Oncology Immediate Care Clinic (ICC)

Nurse PractitionerFull-Time Full Practice Authority

Compensation

Pay not listed

The week · per this posting · weekdays assumed

Ask the employer about the pay range, the work setting, call expectations and time off.

Posted 5mo ago · Verified live

Job Description

Join Mayo Clinic and practice at the top of your license in a fast paced, high impact oncology setting. We are seeking an experienced Acute Care Nurse Practitioner or Physician Assistant to join our Hematology Oncology team.

This unique position blends inpatient and acute ambulatory care so you can keep your skills sharp while caring for complex patients across settings.

What Makes This Role Special

  • Hybrid model with inpatient and clinic experience
  • Strong APP led practice with high autonomy
  • Exposure to advanced and evolving cancer care
  • 12-hour shifts that support flexibility
  • Collaborative, self-scheduling team

Where You Will Work

This full-time role is based in the Immediate Care Clinic ICC, a hospital-based clinic focused on urgent symptom management for patients receiving cancer treatment.

You Will Rotate Across

  • Hematology Consult Service
  • Oncology Consult and Admission Service
  • Immediate Care Clinic

The ICC is open 7 days a week, year-round.

What You Will Do

  • Evaluate and manage patients with acute oncology needs
  • Order and interpret labs, imaging, and diagnostics
  • Prescribe medications and develop treatment plans
  • Provide education and support to patients and families
  • Collaborate with physicians, nursing, and multidisciplinary teams
  • Use evidence-based care to manage complex symptoms

Team and Culture

You will join a small, experienced APP team that works closely together and supports one another. This is a highly collaborative environment where your voice matters and your expertise is valued.

During the selection process you may participate in an OnDemand (pre-recorded) interview that you can complete at your convenience. During the OnDemand interview, a question will appear on your screen, and you will have time to consider each question before responding.

You will have the opportunity to re-record your answer to each question – Mayo Clinic will only see the final recording. The complete interview will be reviewed by a Mayo Clinic staff member, and you will be notified of next steps.

Why Mayo Clinic

Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans – to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.

Benefits Highlights

  • Medical: Multiple plan options.
  • Dental: Delta Dental or reimbursement account for flexible coverage.
  • Vision: Affordable plan with national network.
  • Pre-Tax Savings: HSA and FSAs for eligible expenses.
  • Retirement: Competitive retirement package to secure your future.

Just as our reputation has spread beyond our Minnesota roots, so have our locations.

Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations.

Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is.

Equal Opportunity

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law". Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.

Key Responsibilities

Evaluate and manage patients with acute oncology needs across inpatient and ambulatory settings. Responsibilities include ordering diagnostics, prescribing medications, and collaborating with multidisciplinary teams for urgent symptom management.

Requirements

Requires a Master's degree for NPs or graduation from an accredited PA program with current AZ licensure and certification. Candidates must have at least 2 years of APP experience in Hematology or Oncology, along with active BLS, ACLS, and DEA registrations.

Qualifications

Education
Master's degree (postgraduate degree)
Experience
2+ years of experience

Key Skills

Patient EducationDiagnostic InterpretationTreatment PlanningMultidisciplinary Collaboration

Oncology — Nurse Practitioner Career Context

Of the 50 active Oncology listings this role was benchmarked against, 28% are remote, 54% have no call, 58% require no weekends.

The cost-of-living index for Minnesota is 98.6 (US average = 100; BEA Regional Price Parities (2024)). 63.4% of Minnesota clinicians report burnout symptoms in WeekdayDoc's Burnout Index (2026-01 data).

How many Oncology jobs are remote?
MeasureThis jobMarket
Work-life score6.9 / 10 · top 25% in oncology (np)ranked against 287 Oncology (NP) listingslisting-based score, 0–10
Listed paynot listedOncology median $139k (middle half $139k–$159k)11 comparable listings, Oct 2026
Cost of livingMinnesota index 98.6US average = 100BEA Regional Price Parities (2024)
Work settingon-sitepeers: 28% remote · 54% no call · 58% no weekends50 benchmarked listings
Oncology pay trend+5.5% vs prior quarter—through Sep 2026
Mayo Clinicsilver tier, 71/100 · #7 of 20 for payTop Employers work-life index4 active listings
Sources: WeekdayDoc live listing index (287 Oncology (NP) listings), Top Employers work-life index, BEA Regional Price Parities (2024); as of Oct 2026. Same values as the Weekday Verdict and Market Insights on this page.

Work-Life Balance Analysis

WeekdayDoc's proprietary algorithm rates Acute Care Nurse Practitioner or Physician Assistant - Hematology / Oncology Immediate Care Clinic (ICC) at Mayo Clinic a 6.9 out of 10 for work-life balance — classified as good. This places the position in the top 25% in Oncology (NP) — ranked against 287 active Oncology (NP) listings on WeekdayDoc.

Top Nurse Practitioner Jobs

40 matches · ranked by pay

Salary Distribution

29 jobs
7
<$145k
6
$145k-160k
11
$160k-175k
3
$175k-190k
2
$208k

Annual compensation range

Benefits & Perks

25 jobs
401k / retirement match
92% this job
CME allowance
72% this job
Sign-on bonus
32%
Loan repayment
16%
PSLF eligible
12%

Share of similar jobs offering each benefit

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$100 per hour
#2

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$100 per hour
#3

In-Home Health - Nurse Practitioner or Physician Assistant (Full Time) - Minneapolis, MN

$87k-$187k
#4

Nurse Practitioner-Physician Assistant Sign On Bonus

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+ 38 more · ranked by pay

Work-life snapshot

median 5.1this job 6.9
Better work-life than 80% of Oncology (NP) listings

Listing-based score, 0–10, across 287 comparable listings. Shaded area = the share scoring below this one.

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About Mayo Clinic

Hospitals and Health Care
Rochester, Minnesota
10,000+ employees

Benefits & Perks

Medical: Multiple plan options
Dental: Delta Dental or reimbursement account
Vision: Affordable plan with national network
Pre-Tax Savings: HSA and FSAs
Retirement: Competitive retirement package
Continuing education and advancement opportunities