Nurse Practitioner

Nurse PractitionerPer Diem Physician-Supervised State

Listed compensation

$100-$110/hr

The week · per this posting

Schedule not stated in this posting — no days, weekends, call or nights given.

Ask the employer about the work setting, call expectations, weekend coverage and time off.

Posted 1h ago · Verified live

Job Description

Oncology & Infusion Nurse Practitioner – Per Diem, Fresno, CA

Description of Responsibilities

The Oncology & Infusion Nurse Practitioner is responsible for providing advanced clinical care and clinical oversight for patients receiving chemotherapy, immunotherapy, targeted therapies, biologic therapies, supportive medications, and other specialty infusion therapies at the Fresno clinic.

The Nurse Practitioner conducts comprehensive patient assessments, evaluates treatment readiness, reviews clinical and laboratory parameters, manages treatment-related adverse events and infusion reactions, and collaborates with physicians, pharmacists, and nursing staff to promote safe, evidence-based care.

The role also supports patient education, accurate documentation, quality improvement, staff clinical guidance, and compliance with organizational policies and applicable regulatory standards.

Reporting Relationship

Director of Nursing or designee

Scope of Supervision

Provides clinical oversight and guidance to infusion nursing and pharmacy staff. No direct personnel supervision unless assigned by leadership.

Responsibilities of the Oncology & Infusion Nurse Practitioner include the following:

  • Performs comprehensive initial and ongoing patient assessments, including history, physical examination, medication review, symptom evaluation, and review of relevant clinical information.
  • Evaluates patient readiness for treatment and confirms that ordered treatment parameters have been met before therapy begins.
  • Reviews laboratory values, diagnostic results, treatment protocols, body surface area calculations, dosing, and provider authorization, as applicable, before chemotherapy administration.
  • Provides clinical oversight for the safe administration of chemotherapy, immunotherapy, targeted therapies, biologic therapies, supportive medications, hydration, and other specialty infusion therapies.
  • Administers ordered therapies within the Nurse Practitioner scope of practice, approved privileges, provider orders, manufacturer recommendations, evidence-based guidelines, and organizational policies.
  • Collaborates with the treating physician and pharmacist regarding treatment plans, dose modifications, supportive care, contraindications, precautions, and changes in patient condition.
  • Assesses, identifies, and manages treatment-related adverse events, toxicities, hypersensitivity reactions, anaphylaxis, extravasation, and other infusion-related complications.
  • Initiates appropriate interventions during an adverse event, including stopping or pausing treatment, providing emergency or supportive care within scope, notifying the physician and pharmacist, and escalating to emergency services or a higher level of care when indicated.
  • Reassesses the patient following clinical intervention and documents the event, interventions performed, notifications made, patient response, and disposition.
  • Provides on-site clinical consultation and support to infusion nurses regarding patient assessment, symptom management, treatment parameters, adverse event response, and escalation of care.
  • Ensures independent double-check processes are completed for chemotherapy and other high-alert medications in accordance with organizational requirements.
  • Promotes compliance with hazardous drug handling requirements, required personal protective equipment, spill response procedures, and applicable USP <800>, OSHA, NIOSH, and organizational standards.
  • Assesses and manages venous access devices, including implanted ports, PICCs, central venous catheters, and peripheral IVs, within scope and according to organizational policy and applicable infusion standards.
  • Observes and evaluates patients before, during, and after therapy for therapeutic response, side effects, adverse reactions, and changes in condition.
  • Provides education to patients and caregivers regarding the treatment plan, expected side effects, self-monitoring, symptom management, safety precautions, and when to contact the care team or seek emergency care.
  • Develops, evaluates, and updates the patient plan of care in collaboration with the interdisciplinary team.
  • Obtains, communicates, and documents provider orders and clinical recommendations as permitted within scope of practice.
  • Maintains timely, complete, and accurate documentation of assessments, treatment decisions, interventions, communications, education, and follow-up care in the electronic medical record.
  • Participates in review of adverse events, medication variances, patient safety concerns, and performance improvement activities.
  • Supports the development, review, and implementation of oncology and infusion policies, procedures, clinical workflows, and emergency response processes.

*Required*

Current, active and in good standing registered nurse license in the state of employment

Key Responsibilities

The Nurse Practitioner provides advanced clinical care and oversight for patients receiving oncology and infusion therapies at the Fresno clinic. They conduct comprehensive assessments, manage treatment-related adverse events, and collaborate with the interdisciplinary team to ensure safe, evidence-based care.

Requirements

Candidates must hold a current, active, and in good standing registered nurse license in the state of employment. The role requires clinical expertise in oncology and infusion therapy, including the ability to manage complex treatment protocols and patient safety.

Qualifications

Experience
2+ years of experience

Key Skills

Clinical documentationVenous access device managementMedication safetyInterdisciplinary collaborationAdverse event managementRegulatory complianceEvidence-based practice

Oncology — Nurse Practitioner Career Context

The cost-of-living index for California is 110.7 (US average = 100; BEA Regional Price Parities (2024)), so the posted ~$218k midpoint carries the purchasing power of roughly $197k in an average-cost state. 63.6% of California clinicians report burnout symptoms in WeekdayDoc's Burnout Index (2026-01 data).

Of the 46 active Oncology listings this role was benchmarked against, 11% are remote, 50% have no call, 61% require no weekends.

Oncology pay on WeekdayDoc is up 7.1% vs. the prior quarter (through Sep 2026).

Top contract/1099 Nurse Practitioner Jobs

44 matches · ranked by pay

Salary Distribution22 jobs

9
<$190k
7
$190k-215k
3
$215k-240k
3
$240k-265k

Annual compensation range

Benefits & Perks22 jobs

401k / retirement match
91%
CME allowance
36%
Sign-on bonus
23%
Loan repayment
5%
PSLF eligible
5%

Share of similar jobs offering each benefit

#1

Nurse Practitioner - Addiction Medicine

Downtown Portland Comprehensive Treatment Center · Portland, Oregon

$120 per hour
#2

Physician Assistant OR Nurse Practitioner PRNPer Diem

Concentra · Gilroy, California

$85-$120/hr
#3

Physician Assistant or Nurse Practitioner PRN

$85-$120/hr
#4

Physician Assistant OR Nurse Practitioner PRN

$80-$120/hr
+ 42 more · ranked by pay

Work-life snapshot

median 5.1this job 1.5
Below most Oncology (NP) listings for work-life

Listing-based score, 0–10, across 281 comparable listings. Shaded area = the share scoring below this one.

Living in Fresno

Typical 3-bedroom home value
$380k
Typical market rent
$1,941/mo
Residents’ average commute
22 min
Metro price indexU.S. average = 100
102.2
State income tax
Up to 13.3%
Sources & methodology

Sources: Zillow home values (Aug 2026), Zillow market rents (Aug 2026), U.S. Census ACS 2024 five-year.

BEA 2024 · Fresno, CA metro prices. Housing figures are city-level.

City-level figures. Not a cost-of-living guarantee.

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About California Specialty Pharmacy

Hospitals and Health Care
Whittier, California
51-200 employees