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Prisma Health
Greenville, South Carolina · Hybrid

Registered Nurse (RN)-Nurse Informaticist, FT, Days-Hybrid

Registered NurseFull-Time

Compensation

Pay not listed

The week · per this posting · weekdays assumed

Ask the employer about the pay range, call expectations, weekend coverage and time off.

Posted 1h ago · Verified live

Job Description

Inspire health. Serve with compassion. Be the difference.

Job Summary

Plays a critical role in bridging clinical practice and information technology, contributing to enhanced patient safety and outcomes. Evaluates workflows, provide training, and support system adoption efforts, working collaboratively with interdisciplinary teams and operations.

Essential Functions

All team members are expected to be knowledgeable and compliant with Prisma Health's values: Inspire health. Serve with compassion. Be the difference.

Clinical informatics expert for assigned clinical areas, gaining in-depth knowledge of workflows and documentation requirements to effectively support system optimization and user training. Ensures alignment with best practices and regulatory standards while supporting system optimization and user training.

Participates as the Clinical Informatics representative in meetings and projects to optimize existing clinical systems and implement new ones, improving system usability and patient outcomes.

Provides training and support to clinical staff on healthcare information technology, facilitating system adoption and proficiency.

Analyzes data to identify trends and opportunities for improvement, contributing to evidence-based decision-making and quality improvement initiatives.

Upholds organizational standards and seeks opportunities for professional growth in nursing informatics and project management, enhancing personal and team effectiveness.

Communicates with stakeholders, gathers requirements, and addresses concerns related to clinical informatics initiatives while collaborating with IT teams to troubleshoot system issues and ensure data integrity and security.

Performs other duties as assigned.

Supervisory/Management Responsibilities

This is a non-management job that will report to a supervisor, manager, director or executive.

Minimum Requirements

Education - Bachelor's Degree in Nursing

Experience - Three (3) years Nursing practice, quality improvement, clinical informatics or healthcare operations.

In Lieu Of

In lieu of the BSN requirement above, a nursing diploma or an Associate degree in Nursing may be considered if the applicant signs a Memorandum of Understanding agreeing to enroll in an accredited BSN or MSN program within one year and obtain a BSN or MSN degree within four (4) years.

In lieu of the BSN requirement above, will accept a Master's degree in a related field.

  • Required Certifications, Registrations, Licenses
  • Licensed to practice as an RN in South Carolina.
  • Knowledge, Skills and Abilities
  • Problem-solving skills
  • Ability to understand patient care processes and translate them into technical requirements
  • Ability to work in dynamic environments with shifting schedules and priorities
  • Customer service orientation

Work Shift

Day (United States of America)

Location: Greenville Memorial Hospital

  • Facility
  • Corporate

Department: Informatics BT

Share your talent with us! Our vision is simple: to transform healthcare for the benefits of the communities we serve. The transformation of healthcare requires talented individuals in every role here at Prisma Health.

Key Responsibilities

The Nurse Informaticist bridges clinical practice and information technology to optimize systems and improve patient outcomes. They are responsible for evaluating workflows, providing staff training, and collaborating with interdisciplinary teams to ensure system adoption and data integrity.

Requirements

Candidates must hold a Bachelor's degree in Nursing and possess at least three years of experience in nursing practice, quality improvement, or clinical informatics. A valid South Carolina RN license is required, and candidates must demonstrate strong problem-solving and communication skills.

Qualifications

Education
Bachelor degree
Experience
2+ years of experience

Key Skills

Workflow evaluationData analysisRegulatory complianceStakeholder communicationTroubleshooting

Clinical Informatics — Registered Nurse Career Context

Of the 50 active Registered Nurse listings this role was benchmarked against, 30% are remote, 78% have no call, 74% require no weekends — this position is remote.

Registered Nurse pay on WeekdayDoc is up 6.4% vs. the prior quarter (through Sep 2026).

The cost-of-living index for South Carolina is 93.7 (US average = 100; BEA Regional Price Parities (2024)). 60.6% of South Carolina clinicians report burnout symptoms in WeekdayDoc's Burnout Index (2026-01 data).

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Work-life snapshot

median 3.9this job 2.4
Better work-life than 30% of Registered Nurse roles listings

Listing-based score, 0–10, across 6,062 comparable listings. Shaded area = the share scoring below this one.

  • Hybrid
  • Remote