Nurse Practitioner Jobs in South Dakota
Across 53 live Nurse Practitioner listings in South Dakota, median advertised pay is $168K (75th percentile $200K), based on the 8 that state a salary; South Dakota ranks 18th of 51 states by median advertised pay; the employers with the most openings are Sanford Health (22), Avera Health (12), Commonwealth Medical Services (2).
53+ positions available
Figures are computed from live listings and reviewed by WeekdayDoc’s physician-led editorial team; data as of October 21, 2026. Posted ranges, not accepted offers. How we compute this
These 8 roles pay ~$168k median with 4.5/10 median work-life balance — use these as your benchmarks.
APP - Nurse Practitioner or Physician Assistant | Occupational Medicine
Nurse Practitioner
One to One HealthWatertown, SD
APP - Nurse Practitioner or Physician's Assistant | Obstetrics & Gynecology
Nurse Practitioner or Physician Assistant | Occupational Medicine | PRN
APP - Nurse Practitioner or Physician Assistant | Plastic Surgery
APP - Pediatric Nurse Practitioner | Pediatrics
APP - Nurse Practitioner or Physician Assistant | Family Medicine
APP - Nurse Practitioner or Physician Assistant | Orthopedics & Sports Medicine
APP - Nurse Practitioner or Physician Assistant | Acute Care
APP - Pediatric Nurse Practitioner | Pediatric Surgery
APP - Physician Assistant or Nurse Practitioner | Interventional Pain Management
Nurse Practitioner II, Orthopedic Surgery
APP - Physician Assistant | Sports Medicine/Total Joint
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Nurse Practitioner Pay in South Dakota: Live Market and State Comparison
Live nurse practitioner listings in South Dakota today, then South Dakota against neighboring states and the top payers over the last 12 months of our own postings — so every state is measured alike. Not a salary survey.
- Live listings
- 53
- Live median
- $168k
- 75th $200k · n=8
- 12-mo median
- $138k
- Pay rank
- #18 of 51
- Work-life
- 4.9/10 · #48
- 12-mo postings
- 180
Nurse Practitioner roles in South Dakota advertise $3k above the $135k median across the 51 states we can measure, where California leads at $163k.
| State | Median pay (12 mo) | vs SD | WLB | Postings (12 mo) |
|---|---|---|---|---|
| South Dakota (this page) | $138k | — | 4.9/10 | 180 |
| California#1 | $163k | +$24k | 5.3/10 | 3116 |
| Montanaborders | $146k | +$8k | 5.0/10 | 96 |
| Wyomingborders | $142k | +$3k | 5.8/10 | 93 |
| North Dakotaborders | $142k | +$3k | 5.8/10 | 70 |
| Minnesotaborders | $140k | +$2k | 5.3/10 | 743 |
| Iowaborders | $125k | −$13k | 5.2/10 | 455 |
| Nebraskaborders | $122k | −$16k | 5.3/10 | 187 |
“borders” = shares a border with South Dakota; “#n” = national pay rank among the 51 measured states. Live figures count the listings on WeekdayDoc today (updated Oct 21, 2026); 12-month figures include postings since closed, so states compare on the same basis.
- Most openings on this page:
- Sanford Health (22), Avera Health (12), Commonwealth Medical Services (2)
- Top-rated employers hiring:
- BetterHelp (gold, 96/100), Talkiatry (gold, 95/100), Hiaah (gold, 95/100) (Top Employers work-life index)
A few things worth knowing
About Nurse Practitioner jobs in South Dakota.
How much do nurse practitioners earn in South Dakota?
A reliable salary estimate is unavailable for this sample of nurse practitioners. Compensation varies by role, specialty, location, and schedule. Compare employer-posted pay where disclosed, including its currency and pay period; missing pay is not estimated.
Are there remote or hybrid nurse practitioner jobs available?
Some nurse practitioners roles offer remote or hybrid flexibility. You can filter for telehealth and work-from-home options, and every listing shows its remote status before you apply.
Which nurse practitioner jobs have the best work-life balance?
Every nurse practitioner role on WeekdayDoc is scored for burnout risk using call schedule, weekend and night requirements, and remote flexibility. Among current listings, 29% with no weekends. You can sort by work-life-balance score to surface the lowest-burnout roles first.
Who is hiring nurse practitioners in South Dakota right now?
Employers currently hiring for nurse practitioner roles include Sanford Health, Avera Health, One to One Health. WeekdayDoc aggregates verified openings from these and other organizations, refreshed daily.
How many nurse practitioner jobs in South Dakota are available, and how often are they updated?
There are currently 53 nurse practitioners positions in South Dakota listed, with new roles added as employers post them. Job descriptions are public. Verified sign-in with Google or email gives free access to regular Apply, full search, and standard Market Insights. Saved jobs, My Search, and the dashboard also require verified sign-in. Eligible featured employer listings allow Apply without signup or email. Basic calculators are public and free; optional AI contract analysis, RVU Billing Optimizer, and Schedule Optimizer reports remain paid.
Employers hiring now
Organizations with the most openings in Nurse Practitioner Jobs in South Dakota
- Avera Health12 open roles here · WLB 30/100
Commonwealth Medical Services2 open roles here · WLB 75/100
- EEncompass Wellness P2 open roles here
Akicita Federal1 open role here · WLB 60/100Carbon Health1 open role here · WLB 62/100
Cherokee Federal1 open role here · WLB 59/100
Complete Health1 open role here · WLB 75/100