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Sanford Health
Sioux Falls, South Dakota

APP - Nurse Practitioner or Physician Assistant | ED and Acute Care

Nurse PractitionerFull-Time Full Practice Authority

Listed compensation

$93k-$157k

The week · per this posting · weekdays assumed

Ask the employer about the work setting, call expectations, weekend coverage and time off.

Posted 5mo ago

Job Description

Sanford Health, the largest rural health system in the United States, is dedicated to transforming the health care experience and providing access to world-class health care in America’s heartland.

  • Work Shift: Varies (United States of America) Scheduled
  • Weekly Hours: 40
  • Compensation: Union
  • Position: No Department Details Work in Both ED and Acute Care. 12 Hour shifts either 8-8 or 11-11

ED work done with a ED physician in the department 24/7.

Salary range from $92,820 - $157,212 Summary The Physician Assistant (PA) is a licensed medical professional who practices medicine in collaboration with physicians and other care team members.

The PA evaluates, diagnoses, and manages patient health concerns across the lifespan, provides preventive services, and coordinates care to promote optimal health outcomes. Job Description Perform patient assessments, including medical histories and physical examinations.

Diagnose and manage acute and chronic conditions within scope of practice. Order, review, and interpret diagnostic tests and imaging studies. Prescribe medications, therapies, and other treatments in compliance with regulations.

Educate and counsel patients and families on health maintenance, disease prevention, and treatment plans. May perform procedures & treatments within scope of practice & assist with procedures & treatments when indicated. Collaborate with interdisciplinary team members to ensure continuity of care.

Maintain accurate, timely, and thorough documentation in the electronic medical record (EMR). Participate in quality, safety, and performance improvement activities.

Qualifications Completion of a Physician Assistant program accredited by the ARC-PA or equivalent accrediting program accepted by the state licensing board. Clinical experience in specialty area is preferred but not required. Current licensure as a Physician Assistant in each state of practice.

Current Drug Enforcement Administration (DEA) permit to prescribe controlled substances in each state of practice. State Controlled Substance License (if required by State) Current certification by the National Commission on Certification of Physician Assistants (NCCPA).

Privileging documents and related credentialing requirements will supersede this job description in defining minimum qualifications, criteria, and scope of practice, if variation between documents exists Sanford is an EEO/AA Employer M/F/Disability/Vet.

If you are an individual with a disability and would like to request an accommodation for help with your online application, please call 1-877-949-5678 or send an email to talent@sanfordhealth.org.

The Sanford organization owns and manages multiple distinct brands, including Sanford Health, Marshfield Clinic, and Good Samaritan, as well as Lewis Drug, Sanford Health Equip, Solutions by Sanford, Great Shots, and Blue Rock Bar & Grill.

Sanford Health, the largest rural health system in the United States, is dedicated to transforming the health care experience and providing access to world-class health care in America’s heartland.

Headquartered in Sioux Falls, South Dakota, the organization has 53,000 employees and serves over 2 million patients and nearly 425,000 health plan members across the upper Midwest including South Dakota, North Dakota, Minnesota, Wyoming, Iowa, Wisconsin and the Upper Peninsula of Michigan.

The integrated nonprofit health system includes a network of 56 hospitals, 288 clinic locations, 147 senior care communities, 4,000 physicians and advanced practice providers and nearly 1,500 active clinical trials and studies.

The organization’s transformational virtual care initiative brings patients closer to care with access to 78 specialties. Learn more about Sanford Health’s commitment to shaping the future of rural health care across the lifespan at sanfordhealth.org or Sanford Health News.

Good Samaritan, one of the nation’s largest nonprofit providers of senior care and services, is committed to transforming the aging experience through innovation, compassion and personalized care.

As part of Sanford Health, an integrated nonprofit health system headquartered in Sioux Falls, South Dakota, Good Samaritan serves 10,000 seniors and offers access to a full continuum of care, including 94 rehabilitation and skilled nursing centers, 56 assisted living and memory care facilities, 44 independent living locations and 37 home health and hospice agencies.

The senior care provider delivers services across the upper Midwest, with 70% of residents living in rural communities. Learn more about Good Samaritan’s mission and commitment to delivering high quality senior care in rural America at good-sam.com.

Key Responsibilities

The provider evaluates, diagnoses, and manages patient health concerns in both the Emergency Department and Acute Care settings. Responsibilities include performing physical exams, ordering diagnostic tests, and collaborating with an interdisciplinary team to ensure continuity of care.

Requirements

Candidates must have completed an ARC-PA accredited Physician Assistant program and hold current NCCPA certification. Valid state licensure and a DEA permit to prescribe controlled substances are required.

Qualifications

Education
Professional certificate or licensure

Certifications

DEA License

Key Skills

Patient AssessmentDiagnosisEmergency MedicineChronic Condition ManagementPrescribing MedicationsPatient EducationEMR DocumentationClinical ProceduresInterdisciplinary Collaboration

Emergency Medicine — Nurse Practitioner Career Context

Of the 40 active Nurse Practitioner listings this role was benchmarked against, 33% are remote, 55% have no call, 65% require no weekends.

Nurse Practitioner pay on WeekdayDoc is up 1.1% vs. the prior quarter (through Sep 2026).

Nurse Practitioner by the numbers
MeasureThis jobMarket
Listed pay$93k–$157kNurse Practitioner median $139k (middle half $128k–$159k)284 comparable listings, Oct 2026
Cost-of-living adjusted pay~$141k in purchasing powerSouth Dakota index 88.6 (US = 100)BEA Regional Price Parities (2024)
Nurse Practitioner listings in South Dakota54 active14,239 nationallylive on WeekdayDoc, Oct 2026
Work settingon-sitepeers: 33% remote · 55% no call · 65% no weekends40 benchmarked listings
Nurse Practitioner pay trend+1.1% vs prior quarter—through Sep 2026
Sources: WeekdayDoc live listing index, BEA Regional Price Parities (2024); as of Oct 2026. Same values as the Weekday Verdict and Market Insights on this page.

Location & Logistics

South Dakota has no state income tax, which can significantly increase take-home pay compared to high-tax states. At the posted ~$125k midpoint, that is roughly $5k–$9k a year versus a typical 4–7% state rate.

Top Nurse Practitioner Jobs

20 matches · ranked by pay

Salary Distribution

20 jobs · 19 employers
8
<$160k
9
$160k-185k
1
$195k
2
$210k-235k

Annual compensation range

Benefits & Perks

17 jobs
401k / retirement match
88% this job
CME allowance
59%
Sign-on bonus
53%
Loan repayment
12%
Relocation assistance
6%

Share of similar jobs offering each benefit

#1

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LifeStance Health · Kirkwood, Missouri

$205k-$230k
#2

Psychiatric Mental Health Nurse Practitioner (PMHNP)

Mood Health · Santa Cruz, California

$100-$110/hr
#3

Family Nurse Practitioner (FNP) / Physician Assistant (PA) – Mobile Primary Care

$185k-$195k
#4

Nurse Practitioner-Physician Assistant Sign On Bonus

$129k-$177k
+ 18 more · ranked by pay

Work-life snapshot

median 2.6this job 1.5
Better work-life than 20% of Emergency Medicine (NP) listings

Listing-based score, 0–10, across 267 comparable listings. Shaded area = the share scoring below this one.

Sanford Health logo

About Sanford Health

Hospitals and Health Care
Sioux Falls, SD
10,000+ employees

Benefits & Perks

Health insurance
Dental and vision
Retirement plan
Paid time off
Malpractice coverage

Living in Sioux Falls

Typical 3-bedroom home value
$304k≈ 3.3× annual pay
Typical market rent
$1,302/mo≈ 17% of gross pay
Residents’ average commute
17 min
State income tax
None
Sources & methodology

Sources: Zillow home values (Aug 2026), Zillow market rents (Aug 2026), U.S. Census ACS 2024 five-year.

Ratios use this listing’s gross annual pay. Not a cost-of-living guarantee.