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Charleston Oncology
Charleston, South Carolina

Nurse Practitioner – Hematology/Oncology with BMT & Cellular Therapy Focus

Nurse PractitionerNo callNo nightsFull-Time Physician-Supervised State

Compensation

Pay not listed

The week · per this posting · weekdays assumed

Ask the employer about the pay range, the work setting, weekend coverage and time off.

Posted 1h ago · Verified live

Job Description

Nurse Practitioner – Hematology/Oncology with BMT & Cellular Therapy Focus

Charleston Oncology | Charleston, SC (with travel to Mount Pleasant) | Full-time

No Night Call

You already know how to manage a patient through transplant, engraftment, and everything that can go sideways in between. We are looking for an experienced NP or PA who wants to bring that expertise to a physician-owned practice with a 50-year legacy in Charleston, where you will be a central part of a growing malignant hematology and cellular therapy program, not one of many.

You will partner directly with one of our hematologist/oncologists, on a team with deep BMT and cellular therapy expertise. You will follow patients in both the inpatient and outpatient settings.

The core of the work is malignant hematology (leukemia, lymphoma, myeloma, and MDS) across the full arc of treatment, including BMT and CAR-T. Panels also include a significant benign hematology population and some established general solid tumor patients, so no two clinic days look the same.

Who We Are Looking For

Experienced: 2+ years as an APP in hematology/oncology, with direct BMT and/or CAR-T patient management

Clinically confident: comfortable recognizing and escalating GVHD, CRS, ICANS, neutropenic fever, and other acute complications

Versatile: at ease moving between transplant follow-up, benign hematology, and a general oncology visit in the same day

Program-minded: you want to help shape protocols, workflows, and team education as the program grows

What You Will Do

  • Manage malignant hematology patients across both inpatient and outpatient settings
  • Evaluate and manage benign hematology (e. g., anemia, cytopenias, thrombosis and anticoagulation, bleeding disorders)
  • Provide ongoing care for an established panel of general solid tumor patients
  • Support pre-transplant workup, post-transplant and post-CAR-T follow-up, and long-term survivorship
  • Monitor and manage transplant-related complications, immunosuppression, infection prophylaxis, and transfusion needs
  • Collaborate with physicians, nurses, pharmacists, and fellow APPs on individualized treatment plans
  • Manage your EPIC in-basket and keep patients and referring teams informed

Why Charleston Oncology

Real partnership: Work side by side with experienced hematologist/oncologists; your judgment matters here

Established practice: A 50-year legacy in Charleston; physician-owned and physician-led, with 13 board-certified oncologists and growing

Best of both: You are employed by our physicians, and clinical decisions stay with them, backed by the resources and reach of our hospital partner, Roper St. Francis Healthcare

Access to leadership: Flat structure with leaders who are accessible, so decisions happen in a hallway conversation, not a ticket queue

  • Supportive team: A highly supportive team of physicians, nurses, pharmacists, and fellow APPs
  • Full-service care: Clinical trials, in-house pharmacy, and on-site lab and infusion services
  • Growth: Room to keep growing your skills and knowledge alongside experienced hematologist/oncologists
  • Lifestyle: Practice in Charleston, consistently ranked among the top U.S. cities by Travel + Leisure

Benefits

  • Strong 401(k)
  • Generous paid time off
  • Comprehensive benefits package
  • Free lunch and free onsite parking

Requirements

  • Active NP or PA license (or eligibility for South Carolina licensure) and national board certification
  • 2+ years of hematology/oncology APP experience; BMT and/or CAR-T experience strongly preferred
  • New graduate NPs and PAs with 7+ years of BMT nursing experience will also be considered
  • Comfort with benign hematology and general solid tumor care
  • Inpatient and outpatient experience in a multidisciplinary team
  • Ability to obtain hospital privileges at Roper St. Francis Healthcare
  • EPIC proficiency preferred
  • Ability to practice at more than one Charleston-area location

Ready to Talk?

Send your CV and a brief note about your transplant or cellular therapy experience to Recruiting@charlestononcology.com. Confidential conversations are welcome; we know great APPs are not always actively looking.

Key Responsibilities

Manage malignant hematology patients across inpatient and outpatient settings, including BMT, CAR-T, and general oncology care. Collaborate with a multidisciplinary team to develop treatment plans and monitor for acute transplant-related complications.

Qualifications

Education
Professional certificate or licensure
Experience
2+ years of experience

Key Skills

GVHD recognitionCRS managementICANS managementInpatient careOutpatient careClinical protocols

Oncology — Nurse Practitioner Career Context

Of the 50 active Nurse Practitioner listings this role was benchmarked against, 10% are remote, 66% have no call, 68% require no weekends.

The cost-of-living index for South Carolina is 93.7 (US average = 100; BEA Regional Price Parities (2024)). 60.6% of South Carolina clinicians report burnout symptoms in WeekdayDoc's Burnout Index (2026-01 data).

Nurse Practitioner pay on WeekdayDoc is up 1.1% vs. the prior quarter (through Sep 2026).

Work-Life Balance Analysis

WeekdayDoc's proprietary algorithm rates Nurse Practitioner – Hematology/Oncology with BMT & Cellular Therapy Focus at Charleston Oncology a 6.9 out of 10 for work-life balance — classified as good. This places the position in the top 25% in Oncology (NP) — ranked against 289 active Oncology (NP) listings on WeekdayDoc. Contributing factors include no on-call duties, no night shifts.

Top Nurse Practitioner Jobs

31 matches · ranked by pay

Salary Distribution29 jobs · 25 employers

7
<$155k
12
$155k-170k
5
$170k-185k
4
$185k-200k
1
$206k

Annual compensation range

Benefits & Perks24 jobs

401k / retirement match
88% this job
Sign-on bonus
50%
CME allowance
38%
Loan repayment
21%
Relocation assistance
4%

Share of similar jobs offering each benefit

#1

Nurse Practitioner

Center Well · Virginia

$150k-$206k
#2

CLINICAL LEAD - NURSE PRACTITIONER

C2Q Health Solutions · New York, New York

$160k-$190k
#3

FL14 Float Full Time Float Weekender NP Position

$41.85-$90.13/hr
#4

Nurse Practitioner

$41.85-$90.13/hr
+ 29 more · ranked by pay

Work-life snapshot

median 5.1this job 6.9
Better work-life than 80% of Oncology (NP) listings

Listing-based score, 0–10, across 289 comparable listings. Shaded area = the share scoring below this one.

  • No call
  • No nights

Living in Charleston

Typical 3-bedroom home value
$534k
Typical market rent
$2,312/mo
Residents’ average commute
24 min
Metro price indexU.S. average = 100
101.0
State income tax
Up to 6.5%
Sources & methodology

Sources: Zillow home values (Aug 2026), Zillow market rents (Aug 2026), U.S. Census ACS 2024 five-year.

BEA 2024 · Charleston-North Charleston, SC metro prices. Housing figures are city-level.

City-level figures. Not a cost-of-living guarantee.

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About Charleston Oncology

Benefits & Perks

Strong 401(k)
Generous paid time off
Comprehensive benefits package
Free lunch
Free onsite parking