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Duke
Durham, North Carolina

Clinical Research Nurse Coordinator - Duke Cancer Institute

Registered NurseFull-Time

Listed compensation

$64,966 - $104,996

The week · per this posting

Ask the employer about call expectations, weekend coverage, nights and shift pattern and time off.

Posted 2mo ago

Job Description

School of Medicine

Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools.

Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe.

Composed of more than 2,600 faculty physicians and researchers, nearly 2,000 students, and more than 6,200 staff, the Duke University School of Medicine along with the Duke University School of Nursing, and Duke University Health System comprise Duke Health, a world-class academic medical center.

The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Health Integrated Practice, Duke Primary Care, Duke Home Care and Hospice, Duke Health and Wellness, and multiple affiliations.

Be You.

The Duke Cancer Institute (DCI) is seeking a Clinical Research Nurse Coordinator to join our Breast Clinical Research Program (BRST). In this role, you will combine your clinical nursing expertise with leadership in oncology research to support innovative clinical trials that directly impact patient care.

You will play a key role in coordinating complex breast and gynecologic oncology studies, supporting patients through every phase of participation, and collaborating closely with investigators, sponsors, and multidisciplinary teams across Duke Health.

If you are passionate about oncology nursing, thrive in a research-driven environment, and want to contribute to advancing cancer care, this role offers meaningful work, professional growth, and the opportunity to be part of a nationally recognized academic medical center.

Minimum Requirements

  • Graduation from an accredited BSN, ADN, or Nursing Diploma program
  • BLS certification
  • Minimum of 12 months of clinical nursing experience
  • Current or compact Registered Nurse (RN) licensure in the state of North Carolina
  • Ability to use computing software and web-based applications (e. g., Microsoft Office, electronic systems)

Preferred Qualifications

  • Oncology nursing experience
  • Clinical research or clinical trials experience
  • Experience working with investigational products, chemotherapy administration, or ambulatory care

Other Requirements

  • Must maintain active RN status with the North Carolina Board of Nursing (NCBON)
  • Must maintain compliance with hospital-, unit-, and research-specific training and competency requirements
  • This position is onsite, supporting Duke locations in Durham and Wake Counties (Duke Main Campus and Duke Raleigh Women’s Cancer Center)

Be Bold.

  • Coordinate and manage oncology clinical trials by supporting study start-up, recruitment, screening, consent, enrollment, and long-term follow-up for breast and gynecologic oncology studies, including Phase I–III trials.
  • Provide direct clinical nursing care to adult research participants, including ambulatory medication administration, chemotherapy administration, IV insertion and maintenance, laboratory review, and ongoing patient assessment for adverse events and protocol compliance.
  • Ensure regulatory and study compliance by maintaining study documentation, regulatory binders, delegation of authority logs, adverse event reporting, and institutional and sponsor requirements.
  • Collaborate and communicate effectively with Principal Investigators, sponsors, monitors, and multidisciplinary study teams while serving as the primary liaison for assigned studies.
  • Demonstrate leadership within the research team by mentoring colleagues, contributing to team meetings and committees, supporting professional development, and serving as an expert resource in clinical research operations.

Choose Duke.

At Duke University and the Duke Cancer Institute, you will be part of a mission-driven organization committed to discovery, excellence, and compassionate care. DCI is a nationally recognized leader in cancer research and treatment, offering access to cutting-edge clinical trials and a collaborative academic environment where nurses are valued as essential partners in innovation.

Job Code: 00001203 CLINICAL RESEARCH NURSE COORDINATOR

Job Level: 54

Anticipated Pay Range: Duke University provides an annual base salary range for this position as USD $64,966.00 to USD $104,996.00. Duke University considers factors such as (but not limited to) scope and responsibilities of the position; candidate's work experience, education/training, and key skills; internal peer equity; as well as market and organizational considerations when extending an offer.

Your total compensation goes beyond the dollars on your paycheck. Duke provides comprehensive and competitive medical and dental care programs, generous retirement benefits, and a wide array of family-friendly and cultural programs to eligible team members. Learn more at: https://hr.duke.edu/benefits/

Equal Opportunity Employer: Duke is an Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, (including pregnancy and pregnancy related conditions), sexual orientation, or military status.

Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas—an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard.

All members of our community have a responsibility to uphold these values.

Essential Physical Job Functions

Certain jobs at Duke University and Duke University Health System may include essential job functions that require specific physical and/or mental abilities.

Additional information and reasonable accommodation(s) can be requested with Duke Access and Accommodations Services (email: DAAS@duke.edu; phone:

919-668-1267).

Qualifications

Education
Bachelor degree

Key Skills

Regulatory complianceStudy coordinationData documentation

Work-Life Balance Analysis

WeekdayDoc's proprietary algorithm rates Clinical Research Nurse Coordinator - Duke Cancer Institute at Duke a 7.2 out of 10 for work-life balance — classified as very good. This places the position in the top 10% in Ambulatory Care Nursing (RN) — ranked against 331 active Ambulatory Care Nursing (RN) listings on WeekdayDoc.

Ambulatory Care Nursing — Registered Nurse Career Context

Of the 50 active Ambulatory Care Nursing listings this role was benchmarked against, 32% are remote, 52% have no call, 76% require no weekends.

The cost-of-living index for North Carolina is 94.3 (US average = 100; BEA Regional Price Parities (2024)), so the posted ~$85k midpoint carries the purchasing power of roughly $90k in an average-cost state. 59.2% of North Carolina clinicians report burnout symptoms in WeekdayDoc's Burnout Index (2026-01 data).

Top Registered Nurse Jobs

19 matches · ranked by pay

Salary Distribution19 jobs · 17 employers

7
<$95k
5
$95k-110k
3
$110k-125k
3
$125k-140k
1
$151k

Annual compensation range

Benefits & Perks17 jobs

401k / retirement match
100% this job
CME allowance
29%
Sign-on bonus
18%
Loan repayment
12%

Share of similar jobs offering each benefit

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Work-life snapshot

median 5.1this job 7.2
Among the best 10% of Ambulatory Care Nursing (RN) listings for work-life

Listing-based score, 0–10, across 331 comparable listings. Shaded area = the share scoring below this one.

  • On-site

Living in Durham

Typical 3-bedroom home value
$363k≈ 5.6× annual pay
Typical market rent
$1,659/mo≈ 31% of gross pay
Residents’ average commute
22 min
Metro price indexU.S. average = 100
97.6
State income tax
Up to 4.8%
Sources & methodology

Sources: Zillow home values (Aug 2026), Zillow market rents (Aug 2026), U.S. Census ACS 2024 five-year.

BEA 2024 · Durham-Chapel Hill, NC metro prices. Housing figures are city-level.

Ratios use this listing’s gross annual pay. Not a cost-of-living guarantee.