Clinical Informatics Nurse (Full Time Days)

Registered NurseFull-Time

Compensation

Pay not listed

The week · per this posting · weekdays assumed

Ask the employer about the pay range, the work setting, call expectations and time off.

Posted 7m ago · Verified live

Job Description

St. Luke's is proud of the skills, experience and compassion of its employees. The employees of St. Luke's are our most valuable asset!

Individually and together, our employees are dedicated to satisfying the mission of our organization which is an unwavering commitment to excellence as we care for the sick and injured; educate physicians, nurses and other health care providers; and improve access to care in the communities we serve, regardless of a patient's ability to pay for health care.

Responsible for enhancing, supporting and maintaining an application(s) within the St. Luke’s Health System with an emphasis on patient care impact, clinical outcomes and quality improvement; in collaboration with other clinical and IT employees.

Optimize the application by serving as a liaison between the end user and IT. Will work with cross functional teams and St. Luke’s clients by providing information on system functionality and configuration of new tools to increase end user productivity within the application(s).

In conjunction with the IT training team, will assist with communicating all necessary application changes, enhancements and procedures to all necessary internal and external department teams.

Job Duties and Responsibilities

  • Assists with the integration of information systems into the clinical areas to support quality patient care.
  • Participates in the analysis of clinical environments and evaluation and implementation of emerging technologies.
  • Provides support for end users of clinical applications.
  • Assists in workflow analysis related to use of information systems for maximum efficiency.
  • Serves as a resource to staff and providers for resolving educational and workflow issues.

Collaborates with staff and providers in clinical areas to obtain ideas for system enhancements. Collaborates with medical informatics and business relationship managers to implement solutions and innovations.

Participates in clinical information technology implementation and upgrades through design input and validation, testing, and facilitation of at-the-elbow support when available.

Develops and maintains clinical information technology and analytics expertise.

Provides assistance and expertise in leveraging adoption of new predictive analytic models into clinician workflow.

Maintain current knowledge of information technology by attending appropriate continuing education training/seminars and reading related periodicals.

Utilizes knowledge of clinical practice to determine clinical information technology functional requirements.

Solid understanding of operational / clinical services and information / work flow of assigned areas ability to analyze, diagnoses, support and implement process/operational change

Will interact and collaborate with all levels of healthcare personnel; IT Management, Clinicians, Consultants and Administrators.

  • Participates in Hospital/Network Committees as assigned.
  • Helps analyze data on performance metrics for quality and performance initiatives.
  • Act as preceptors to Informatics students as part of professional development and contribution to our discipline.
  • Strong Customer Service Orientation and ability to follow through on issue resolution.

Physical and Sensory Demands

Sitting for up to 7 hours per day, 4 hours at a time; standing for up to 7 hours per day, 4 hours at a time; walking for up to 2 hours a day, 1 hour at a time. Requires crouching, kneeling, and lifting of objects weighing up to 60 pounds, pushing objects weighing up to 80 pounds.

Requires hand and finger dexterity to perform repairs of small equipment and to use computer equipment. Seeing as it relates to general, near, color, and peripheral vision. Hearing as it relates to normal and telephone conversations.

Education

Bachelor's Degree required. Bachelor's degree in nursing preferred. Master's Degree preferred. Registered Nurse License required.

Training and Experience

Obtain and maintain an Epic clinical contact build/informatics OR obtain one Epic certification within 2 years of hire. 3- 5 years nursing clinical experience preferred. Information technology, healthcare informatics or equivalent work preferred. Demonstrated competence as a professional nurse in recent practice.

Demonstrated experience and effectiveness as a clinician. Utilization of clinical information systems required. PC and Printer knowledge and experience is preferred. Understanding of clinical analytics, including quality measurement and indicators. Epic/EMR experience is preferred.

MS Office is required Proficient in Excel. Proficient in Power Point. General, Radiology, Pharmacy, Nursing, Physician Services, Laboratory, Ambulatory Care, Patient Care Services, and other specialty healthcare areas.

Please complete your application using your full legal name and current home address. Be sure to include employment history for the past seven (7) years, including your present employer.

Additionally, you are encouraged to upload a current resume, including all work history, education, and/or certifications and licenses, if applicable. It is highly recommended that you create a profile at the conclusion of submitting your first application. Thank you for your interest in St. Luke's!!

St. Luke's University Health Network is an Equal Opportunity Employer.

Key Responsibilities

The Clinical Informatics Nurse enhances and maintains clinical applications while serving as a liaison between end users and IT to optimize system functionality. They participate in workflow analysis, provide end-user support, and collaborate with cross-functional teams to implement clinical technology solutions.

Requirements

A Bachelor's degree and a valid Registered Nurse license are required for this position. Candidates should have 3-5 years of clinical nursing experience and proficiency in MS Office, with Epic or EMR experience preferred.

Qualifications

Education
Bachelor degree
Experience
2+ years of experience

Key Skills

Data analysisSystem configurationPredictive analyticsPowerPointProcess improvementClinical documentation

Ambulatory Care Nursing — Registered Nurse Career Context

Of the 50 active Ambulatory Care Nursing listings this role was benchmarked against, 30% are remote, 52% have no call, 72% require no weekends.

The cost-of-living index for Pennsylvania is 97.6 (US average = 100; BEA Regional Price Parities (2024)). 61.7% of Pennsylvania clinicians report burnout symptoms in WeekdayDoc's Burnout Index (2026-01 data).

How many Ambulatory Care Nursing jobs are remote?
MeasureThis jobMarket
Listed paynot listedAmbulatory Care Nursing median $95k (middle half $90k–$100k)16 comparable listings, Oct 2026
Cost of livingPennsylvania index 97.6US average = 100BEA Regional Price Parities (2024)
Ambulatory Care Nursing listings in Pennsylvania14 active396 nationallylive on WeekdayDoc, Oct 2026
Work settingon-sitepeers: 30% remote · 52% no call · 72% no weekends50 benchmarked listings
Ambulatory Care Nursing pay trend−1.1% vs prior quarter—through Sep 2026
Sources: WeekdayDoc live listing index, BEA Regional Price Parities (2024); as of Oct 2026. Same values as the Weekday Verdict and Market Insights on this page.

Top Registered Nurse Jobs

42 matches · ranked by pay

Salary Distribution

41 jobs · 37 employers
13
<$95k
8
$95k-115k
14
$115k-135k
6
$135k-155k

Annual compensation range

Benefits & Perks

36 jobs
401k / retirement match
92%
Sign-on bonus
17%
Loan repayment
8%
CME allowance
8% this job
PSLF eligible
8%

Share of similar jobs offering each benefit

#1

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Telecare · San Leandro, California

$125k-$155k
#2

Asst. Director of Nursing - Ambulatory Care - Newkirk Avenue

Maimonides Medical Center · Brooklyn, New York

$136,708 - $150,000
#3

Psychiatric Nurse Manager - Women's Mental Health

$150k
#4

Director of Nursing

$128k-$146k
+ 40 more · ranked by pay

Work-life snapshot

median 5.1this job 3.0
Better work-life than 20% of Ambulatory Care Nursing (RN) listings

Listing-based score, 0–10, across 388 comparable listings. Shaded area = the share scoring below this one.

St. Luke's University Health Network logo

About St. Luke's University Health Network

Hospitals and Health Care
Bethlehem, PA
10,000+ employees

Benefits & Perks

Health Insurance
Epic certification support
Continuing education

Living in Allentown

Typical 3-bedroom home value
$312k
Typical market rent
$1,710/mo
Residents’ average commute
25 min
Metro price indexU.S. average = 100
100.0
State income tax
Up to 3.1%
Sources & methodology

Sources: Zillow home values (Aug 2026), Zillow market rents (Aug 2026), U.S. Census ACS 2024 five-year.

BEA 2024 · Allentown-Bethlehem-Easton, PA-NJ metro prices. Housing figures are city-level.

City-level figures. Not a cost-of-living guarantee.