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Nurse Practitioner Jobs in Mississippi

Across 103 live Nurse Practitioner listings in Mississippi, median advertised pay is $281K (75th percentile $300K), based on the 28 that state a salary; Mississippi ranks 34th of 51 states by median advertised pay; the employers with the most openings are Matrix Medical Network (15), Singing River Health System (8), Fast Pace Health (7).

103+ positions available

Figures are computed from live listings and reviewed by WeekdayDoc’s physician-led editorial team; data as of October 21, 2026. Posted ranges, not accepted offers. How we compute this

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103 jobs

These 28 roles pay ~$281k median with 7.2/10 median work-life balance — use these as your benchmarks.

Memorial Hospital at Gulfport logo

Physician Assistant or Nurse Practitioner - Cardiology Physicians - FT

Memorial Hospital at GulfportGulfport, MS

Nurse Practitioner
Pay not disclosed
Memorial Hospital at Gulfport logo

Nurse Practitioner or Physicians Assistant - Cardiology Physicians - FT

Memorial Hospital at GulfportGulfport, MS

Nurse Practitioner
Pay not disclosed
The Employment Team at Hattiesburg Clinic, P.A. logo

Nurse Practitioner - Hospital Care Service

Employment Team at Hattiesburg Clinic, P.AHattiesburg, MS

Nurse Practitioner
Pay not disclosed
The Employment Team at Hattiesburg Clinic, P.A. logo

Nurse Practitioner or Physician Assistant Talent Pool

Employment Team at Hattiesburg Clinic, P.AHattiesburg, MS

Nurse Practitioner
Pay not disclosed
South Central Regional Medical Center logo

PHYSICIAN ASSISTANT / NURSE PRACTITIONER - URGENT CARE

South Central Regional Medical CenterLaurel, MS

Nurse Practitioner
Pay not disclosed
Singing River Health System logo

Acute Care Nurse Practitioner | Singing River Cardiology Clinic - Gulfport

Singing River Health SystemGulfport, MS

Nurse Practitioner
Pay not disclosed
Memorial Hospital at Gulfport logo

Nurse Practitioner or Physician Assistant - Pediatric Physicians Clinic - FT

Memorial Hospital at GulfportOcean Springs, MS

Nurse Practitioner
Pay not disclosed
Ochsner Health logo

Nurse Practitioner or Physician Assistant - Primary Care

Ochsner HealthCollinsville, MS

Nurse Practitioner
Pay not disclosed
Singing River Health System logo

Nurse Practitioner | Interventional Pain Management

Singing River Health SystemGulfport, MS

Nurse Practitioner
Pay not disclosed
UnitedHealth Group logo

Hospice Nurse Practitioner - PRN

UnitedHealth GroupEmployer score · SilverPhiladelphia, MS

TYLER HOLMES MEMORIAL HOSPITAL logo

Nurse Practitioner

Tyler Holmes Memorial HospitalMississippi

Nurse Practitioner
$55.52-$67.2 per hour
Marathon Health logo

PRN Nurse Practitioner - Tupelo, MS

Marathon HealthEmployer score · SilverTupelo, MS

Nurse Practitioner
$60.00-75.00 per hour
ADDICTION AND MENTAL HEALTH SERVICES logo

Family Nurse Practitioner

Addiction and Mental Health ServicesLucedale, MS

Nurse Practitioner
Pay not disclosed
Singing River Health System logo

Nurse Practitioner - Primary Care

Singing River Health SystemPascagoula, MS

Nurse Practitioner
Pay not disclosed
Methodist Rehabilitation logo

Nurse Practitioner - IP Reviewer - Community Outreach (302)

Methodist RehabilitationJackson, MS

Nurse Practitioner
Pay not disclosed

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Nurse Practitioner Pay in Mississippi: Live Market and State Comparison

Live nurse practitioner listings in Mississippi today, then Mississippi against neighboring states and the top payers over the last 12 months of our own postings — so every state is measured alike. Not a salary survey.

Live listings
103
Live median
$281k
75th $300k · n=28
12-mo median
$133k
Pay rank
#34 of 51
Work-life
5.1/10 · #44
12-mo postings
348

Nurse Practitioner pay in Mississippi sits level with the $135k median across the 51 states we can measure, where California leads at $163k.

Nurse Practitioner median pay and work-life-balance score, Mississippi compared with neighboring states and the highest-paying states
StateMedian pay (12 mo)vs MSWLBPostings (12 mo)
Mississippi (this page)$133k—5.1/10348
California#1$163k+$30k5.3/103116
Washington#2$153k+$20k5.5/10903
Oregon#3$152k+$19k6.0/10663
Louisianaborders$135k+$3k4.8/10572
Alabamaborders$131k−$2k4.9/10361
Tennesseeborders$128k−$5k5.2/10882
Arkansasborders$127k−$6k5.1/10391

“borders” = shares a border with Mississippi; “#n” = national pay rank among the 51 measured states. Live figures count the listings on WeekdayDoc today (updated Oct 21, 2026); 12-month figures include postings since closed, so states compare on the same basis.

Most openings on this page:
Matrix Medical Network (15), Singing River Health System (8), Fast Pace Health (7)
Top-rated employers hiring:
BetterHelp (gold, 96/100), Talkiatry (gold, 95/100), Hiaah (gold, 95/100) (Top Employers work-life index)

A few things worth knowing

About Nurse Practitioner jobs in Mississippi.

How much do nurse practitioners earn in Mississippi?

A reliable salary estimate is unavailable for this sample of nurse practitioners. Compensation varies by role, specialty, location, and schedule. Compare employer-posted pay where disclosed, including its currency and pay period; missing pay is not estimated.

Are there remote or hybrid nurse practitioner jobs available?

Some nurse practitioners roles offer remote or hybrid flexibility. You can filter for telehealth and work-from-home options, and every listing shows its remote status before you apply.

Which nurse practitioner jobs have the best work-life balance?

Every nurse practitioner role on WeekdayDoc is scored for burnout risk using call schedule, weekend and night requirements, and remote flexibility. You can sort by work-life-balance score to surface the lowest-burnout roles first.

Who is hiring nurse practitioners in Mississippi right now?

Employers currently hiring for nurse practitioner roles include Singing River Health System, Memorial Hospital at Gulfport, The Employment Team at Hattiesburg Clinic, P.A., Canopy Children's Solutions, and others. WeekdayDoc aggregates verified openings from these and other organizations, refreshed daily.

How many nurse practitioner jobs in Mississippi are available, and how often are they updated?

There are currently 103 nurse practitioners positions in Mississippi listed, with new roles added as employers post them. Job descriptions are public. Verified sign-in with Google or email gives free access to regular Apply, full search, and standard Market Insights. Saved jobs, My Search, and the dashboard also require verified sign-in. Eligible featured employer listings allow Apply without signup or email. Basic calculators are public and free; optional AI contract analysis, RVU Billing Optimizer, and Schedule Optimizer reports remain paid.