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Nurse Practitioner Jobs in Mississippi

Across 103 live Nurse Practitioner listings in Mississippi, median advertised pay is $281K (75th percentile $300K), based on the 28 that state a salary; Mississippi ranks 34th of 51 states by median advertised pay; the employers with the most openings are Matrix Medical Network (15), Singing River Health System (8), Fast Pace Health (7).

103+ positions available

Figures are computed from live listings and reviewed by WeekdayDoc’s physician-led editorial team; data as of October 21, 2026. Posted ranges, not accepted offers. How we compute this

Prioritize:

103 jobs

These 28 roles pay ~$281k median with 7.2/10 median work-life balance — use these as your benchmarks.

Baptist logo

Nurse Practitioner Interventional Radiology

BaptistMeridian, MS

Nurse Practitioner
Pay not disclosed
30+ days ago
Addiction and Mental Health Services logo

Psychiatric Nurse Practitioner

Addiction and Mental Health ServicesWoodland, MS

Nurse Practitioner
Pay not disclosed
30+ days ago
Addiction and Mental Health Services logo

Psychiatric Nurse Practitioner

Addiction and Mental Health ServicesSouthaven, MS

Nurse Practitioner
Pay not disclosed
30+ days ago
Semrhi logo

Family Nurse Practitioner

SemrhiPurvis, MS

Nurse Practitioner
Pay not disclosed
30+ days ago
Fast Pace Health logo

Family Nurse Practitioner

Fast Pace HealthCanton, MS

Nurse Practitioner
Pay not disclosed
30+ days ago
Mississippi Sports Medicine & Orthopaedic Center logo

NURSE PRACTITIONER - URGENT CARE

Mississippi Sports Medicine & Orthopaedic CenterMississippi

Nurse Practitioner
Pay not disclosed
30+ days ago
Fast Pace Health logo

Family Nurse Practitioner

Fast Pace HealthClarksdale, MS

Nurse Practitioner
Pay not disclosed
30+ days ago
Sonder Mind logo

Psychiatric Nurse Practitioner

Sonder MindEmployer score · GoldRemote

Nurse Practitioner
$248 per hour
30+ days ago
Freedom Magnolia logo

Nurse Practitioner-Psych

Freedom MagnoliaMississippi

Nurse Practitioner
Pay not disclosed
30+ days ago
Enhabit Home Health & Hospice logo

Nurse Practitioner (NP) - Hospice - PRN

Enhabit Home Health & HospiceMcComb, MS

Nurse Practitioner
Pay not disclosed
30+ days ago
Fast Pace Health logo

Family Nurse Practitioner

Fast Pace HealthSouthaven, MS

Nurse Practitioner
Pay not disclosed
30+ days ago
Fast Pace Health logo

Family Nurse Practitioner-Float

Fast Pace HealthColumbus, MS

Nurse Practitioner
Pay not disclosed
30+ days ago
Hybrid
Segue Health Management logo

Adult Nurse Practitioner- Southaven

Segue Health ManagementSouthaven, MS

Nurse Practitioner
$115,000-$135,000
30+ days ago
Segue Health Management logo

Adult Nurse Practitioner- Columbus, MS

Segue Health ManagementMississippi, United States

Nurse Practitioner
$115,000-$135,000
BEACON BEHAVIORAL SUPPORT SERVICES logo

Psychiatric Mental Health Nurse Practitioner- Starkville

Beacon Behavioral Support ServicesStarkville, MS

Nurse Practitioner
Pay not disclosed

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Nurse Practitioner Pay in Mississippi: Live Market and State Comparison

Live nurse practitioner listings in Mississippi today, then Mississippi against neighboring states and the top payers over the last 12 months of our own postings — so every state is measured alike. Not a salary survey.

Live listings
103
Live median
$281k
75th $300k · n=28
12-mo median
$133k
Pay rank
#34 of 51
Work-life
5.1/10 · #44
12-mo postings
346

Nurse Practitioner pay in Mississippi sits level with the $135k median across the 51 states we can measure, where California leads at $163k.

Nurse Practitioner median pay and work-life-balance score, Mississippi compared with neighboring states and the highest-paying states
StateMedian pay (12 mo)vs MSWLBPostings (12 mo)
Mississippi (this page)$133k—5.1/10346
California#1$163k+$30k5.3/103106
Washington#2$153k+$20k5.5/10905
Oregon#3$152k+$19k6.0/10663
Louisianaborders$135k+$3k4.8/10571
Alabamaborders$131k−$2k4.9/10361
Tennesseeborders$128k−$5k5.2/10878
Arkansasborders$127k−$6k5.1/10390

“borders” = shares a border with Mississippi; “#n” = national pay rank among the 51 measured states. Live figures count the listings on WeekdayDoc today (updated Oct 21, 2026); 12-month figures include postings since closed, so states compare on the same basis.

Most openings on this page:
Matrix Medical Network (15), Singing River Health System (8), Fast Pace Health (7)
Top-rated employers hiring:
BetterHelp (gold, 96/100), Talkiatry (gold, 95/100), Hiaah (gold, 95/100) (Top Employers work-life index)

A few things worth knowing

About Nurse Practitioner jobs in Mississippi.

How much do nurse practitioners earn in Mississippi?

A reliable salary estimate is unavailable for this sample of nurse practitioners. Compensation varies by role, specialty, location, and schedule. Compare employer-posted pay where disclosed, including its currency and pay period; missing pay is not estimated.

Are there remote or hybrid nurse practitioner jobs available?

Yes — about 15% of current nurse practitioners listings offer remote or hybrid work. You can filter for telehealth and work-from-home options, and every listing shows its remote status before you apply.

Which nurse practitioner jobs have the best work-life balance?

Every nurse practitioner role on WeekdayDoc is scored for burnout risk using call schedule, weekend and night requirements, and remote flexibility. You can sort by work-life-balance score to surface the lowest-burnout roles first.

Who is hiring nurse practitioners in Mississippi right now?

Employers currently hiring for nurse practitioner roles include Fast Pace Health, Addiction and Mental Health Services, Segue Health Management, Baptist, and others. WeekdayDoc aggregates verified openings from these and other organizations, refreshed daily.

How many nurse practitioner jobs in Mississippi are available, and how often are they updated?

There are currently 103 nurse practitioners positions in Mississippi listed, with new roles added as employers post them. Job descriptions are public. Verified sign-in with Google or email gives free access to regular Apply, full search, and standard Market Insights. Saved jobs, My Search, and the dashboard also require verified sign-in. Eligible featured employer listings allow Apply without signup or email. Basic calculators are public and free; optional AI contract analysis, RVU Billing Optimizer, and Schedule Optimizer reports remain paid.