Nurse Practitioner Jobs in Mississippi
Across 103 live Nurse Practitioner listings in Mississippi, median advertised pay is $281K (75th percentile $300K), based on the 28 that state a salary; Mississippi ranks 34th of 51 states by median advertised pay; the employers with the most openings are Matrix Medical Network (15), Singing River Health System (8), Fast Pace Health (7).
103+ positions available
Figures are computed from live listings and reviewed by WeekdayDoc’s physician-led editorial team; data as of October 21, 2026. Posted ranges, not accepted offers. How we compute this
These 28 roles pay ~$281k median with 7.2/10 median work-life balance — use these as your benchmarks.
Nurse Practitioner (PRN) - In-Home Health Assessments
Matrix Medical NetworkEmployer score · SilverGloster, MS
Nurse Practitioner (PRN) - In-Home Health Assessments
Matrix Medical NetworkEmployer score · SilverLiberty, MS
CLINIC NURSE PRACTITIONER
Mississippi Sports Medicine & Orthopaedic CenterOxford, MS
Field Nurse Practitioner - Jackson County, MS
AdvantmedEmployer score · SilverPascagoula, MS
Nurse Practitioner (PRN) - In-Home Health Assessments
Matrix Medical NetworkEmployer score · SilverMississippi
Nurse Practitioner - Clinic
Cardiovascular Institute of the SouthMeridian, MS
Psychiatric Mental Health Nurse Practitioner - Contract
Choices Coordinated Care SolutionsEmployer score · SilverPicayune, MS
Palliative Nurse Practitioner
UnitedHealth GroupEmployer score · SilverJackson, MS
Dermatology Nurse Practitioner or Physician Assistant
NURSE PRACTITIONER / PHYSICIAN ASSISTANT - ELLISVILLE FAMILY MED
South Central Regional Medical CenterLaurel, MS
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Nurse Practitioner Pay in Mississippi: Live Market and State Comparison
Live nurse practitioner listings in Mississippi today, then Mississippi against neighboring states and the top payers over the last 12 months of our own postings — so every state is measured alike. Not a salary survey.
- Live listings
- 103
- Live median
- $281k
- 75th $300k · n=28
- 12-mo median
- $133k
- Pay rank
- #34 of 51
- Work-life
- 5.1/10 · #44
- 12-mo postings
- 348
Nurse Practitioner pay in Mississippi sits level with the $135k median across the 51 states we can measure, where California leads at $163k.
| State | Median pay (12 mo) | vs MS | WLB | Postings (12 mo) |
|---|---|---|---|---|
| Mississippi (this page) | $133k | — | 5.1/10 | 348 |
| California#1 | $163k | +$30k | 5.3/10 | 3116 |
| Washington#2 | $153k | +$20k | 5.5/10 | 903 |
| Oregon#3 | $152k | +$19k | 6.0/10 | 663 |
| Louisianaborders | $135k | +$3k | 4.8/10 | 572 |
| Alabamaborders | $131k | −$2k | 4.9/10 | 361 |
| Tennesseeborders | $128k | −$5k | 5.2/10 | 882 |
| Arkansasborders | $127k | −$6k | 5.1/10 | 391 |
“borders” = shares a border with Mississippi; “#n” = national pay rank among the 51 measured states. Live figures count the listings on WeekdayDoc today (updated Oct 21, 2026); 12-month figures include postings since closed, so states compare on the same basis.
- Most openings on this page:
- Matrix Medical Network (15), Singing River Health System (8), Fast Pace Health (7)
- Top-rated employers hiring:
- BetterHelp (gold, 96/100), Talkiatry (gold, 95/100), Hiaah (gold, 95/100) (Top Employers work-life index)
A few things worth knowing
About Nurse Practitioner jobs in Mississippi.
How much do nurse practitioners earn in Mississippi?
A reliable salary estimate is unavailable for this sample of nurse practitioners. Compensation varies by role, specialty, location, and schedule. Compare employer-posted pay where disclosed, including its currency and pay period; missing pay is not estimated.
Are there remote or hybrid nurse practitioner jobs available?
Yes — about 5% of current nurse practitioners listings offer remote or hybrid work. You can filter for telehealth and work-from-home options, and every listing shows its remote status before you apply.
Which nurse practitioner jobs have the best work-life balance?
Every nurse practitioner role on WeekdayDoc is scored for burnout risk using call schedule, weekend and night requirements, and remote flexibility. Among current listings, 30% with no on-call and 70% with no weekends. You can sort by work-life-balance score to surface the lowest-burnout roles first.
Who is hiring nurse practitioners in Mississippi right now?
Employers currently hiring for nurse practitioner roles include Matrix Medical Network, The Employment Team at Hattiesburg Clinic, P.A., Empatia, Mississippi Sports Medicine & Orthopaedic Center, and others. WeekdayDoc aggregates verified openings from these and other organizations, refreshed daily.
How many nurse practitioner jobs in Mississippi are available, and how often are they updated?
There are currently 103 nurse practitioners positions in Mississippi listed, with new roles added as employers post them. Job descriptions are public. Verified sign-in with Google or email gives free access to regular Apply, full search, and standard Market Insights. Saved jobs, My Search, and the dashboard also require verified sign-in. Eligible featured employer listings allow Apply without signup or email. Basic calculators are public and free; optional AI contract analysis, RVU Billing Optimizer, and Schedule Optimizer reports remain paid.
Employers hiring now
Organizations with the most openings in Nurse Practitioner Jobs in Mississippi
- Matrix Medical Network15 open roles here · WLB 74/100
Singing River Health System8 open roles here · WLB 32/100Fast Pace Health7 open roles here · WLB 75/100
Employment Team at Hattiesburg Clinic, P.A4 open roles here · WLB 65/100
Memorial Hospital at Gulfport4 open roles here · WLB 73/100- South Central Regional Medical Center4 open roles here · WLB 62/100
Addiction and Mental Health Services3 open roles here · WLB 75/100