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Lab
Durham, North Carolina

Oncologist, Medical Director, Clinical Development - MRD

Medical Affairs 8.0 Work-LifeNo weekendsNo nightsFull-Time

Compensation

Pay not listed

The week · per this posting · Monday – FridayWeekdays only

Ask the employer about the pay range, the work setting, call expectations and time off.

Posted 2mo ago

Job Description

Labcorp is a global leader in laboratory services, providing the insights and answers that help healthcare providers, patients, researchers, pharmaceutical companies and health systems make confident decisions and improve outcomes.

Through our unparalleled science, data, technology and laboratory network, we advance diagnostics, accelerate innovation and help address some of the world’s most important health challenges.

As we shape the future of healthcare, we are leveraging advanced technologies, intelligent digital solutions and data-driven innovation across our operations to enhance how work gets done and deliver greater value to customers and patients.

With our global scale and deep expertise, you’ll have the opportunity to do meaningful work, grow your career and make a real impact on people’s health around the world. Together, we’re improving health and improving lives.

Labcorp is seeking a Medical Director, Clinical Development – MRD Portfolio (Solid Tumors) to join our team.

Work Schedule: Monday – Friday, 1st shift

Job Summary

The Medical Director, Clinical Development – MRD Portfolio is a key physician leader responsible for shaping and executing the clinical development strategy for Labcorp Oncology's minimal residual disease (MRD) portfolio across solid tumors. This individual will provide medical leadership for the development, validation, and clinical adoption of MRD and circulating tumor DNA (ctDNA)-based technologies, advancing precision oncology through innovative molecular diagnostics that improve patient outcomes across the cancer care continuum.

As the clinical development lead for the MRD portfolio, this role will drive the generation of clinical evidence required to support product development, clinical validity, utility, reimbursement, guideline inclusion, and integration into routine oncology practice. The Medical Director will lead a team of disease-focused clinical development physicians and work closely with partners across research and development, operations, biostatistics, medical affairs, market access, regulatory affairs, commercial, and executive leadership to develop and execute a cohesive clinical strategy across multiple tumor types and indications.

The successful candidate will be a board-certified medical oncologist with broad expertise across solid tumors, a strong background in clinical research and development, and a passion for advancing the role of molecular diagnostics in cancer care. This individual will serve as a key scientific representative for Labcorp Oncology, partnering with leading investigators, professional societies, cooperative groups, payers, and other external stakeholders to establish MRD testing as a critical component of personalized cancer management.

Job Responsibilities

Clinical Development Leadership

Serve as the clinical development lead for Labcorp Oncology's MRD portfolio across solid tumors, providing strategic medical leadership for evidence generation, product development, and clinical adoption initiatives.

Develop and execute the clinical development strategy supporting MRD and ctDNA-based technologies across multiple tumor types and disease settings.

Lead the design, development, and execution of clinical studies and evidence-generation programs that establish the clinical validity, clinical utility, and health-economic value of MRD testing.

Direct clinical strategies supporting MRD applications, including minimal residual disease detection, recurrence monitoring, treatment response assessment, risk stratification, treatment selection, and clinical trial enrichment.

Lead the development and implementation of clinical studies that support integration of MRD testing into clinical care pathways and routine oncology practice.

Partner with operations, biostatistics, R&D, and market access teams on study design, protocol development, endpoint selection, statistical analysis plans, study oversight, and interpretation of results.

Recruit, engage, and maintain relationships with leading principal investigators, cooperative groups, and academic research centers to support company-sponsored clinical studies and strategic research collaborations.

Oversee study execution in partnership with medical operations, including protocol development, site selection, enrollment strategy, timeline management, budget oversight, and study governance.

Translate emerging clinical data into actionable clinical development recommendations and portfolio strategies.

Support investigator-initiated studies, strategic research collaborations, and real-world evidence programs that expand the evidence base supporting MRD testing.

Portfolio and Product Leadership

Provide medical leadership for the MRD portfolio throughout the product lifecycle, from concept development through commercialization and lifecycle management.

Advise on product development strategy by identifying unmet clinical needs, new indication opportunities, emerging market trends, and future applications of MRD technologies.

Define intended use populations, clinical claims, test report content, validation requirements, and evidence-generation strategies necessary to support product development and adoption.

Partner with R&D teams to guide assay development, biomarker strategy, and next-generation product innovation.

Evaluate competitive technologies, emerging biomarkers, and evolving standards of care to inform portfolio strategy and prioritization.

Provide clinical input into product roadmaps, indication expansion opportunities, and future growth areas within the oncology portfolio.

Support development of clinical and scientific evidence required for successful product launches and lifecycle management activities.

Clinical Utility, Market Access, and Adoption

Partner with market access teams to develop and execute evidence-generation strategies supporting payer coverage, reimbursement, and health-system adoption.

Provide medical leadership for studies designed to demonstrate clinical utility, impact on physician decision-making, patient outcomes, and economic value.

Support interactions with payers, policy stakeholders, and guideline organizations by communicating the clinical rationale and value proposition of MRD testing.

Contribute to strategies supporting inclusion of MRD testing within clinical practice guidelines, treatment pathways, and value-based care models.

Ensure clinical development priorities and evidence-generation plans align with reimbursement, market access, and adoption objectives.

Investigator and External Scientific Leadership

Build and maintain relationships with leading oncology investigators, academic medical centers, cooperative groups, and professional societies across solid tumors.

Recruit and engage principal investigators and clinical sites to participate in company-sponsored studies and strategic collaborations.

Serve as a scientific leader and ambassador for Labcorp Oncology within the oncology community.

Represent Labcorp Oncology at scientific congresses, advisory boards, investigator meetings, and industry forums.

Engage key opinion leaders to support clinical development strategy, evidence generation, and long-term portfolio planning.

Medical Affairs and Scientific Communications

Provide medical leadership and post-launch support for MRD products, including interpretation of clinical evidence, management of complex clinical questions, and support for appropriate clinical implementation.

Serve as a clinical resource for healthcare providers regarding MRD testing and integration of results into patient management.

Oversee medical education initiatives and scientific communications supporting MRD adoption across solid tumors, including tumor boards, webinars, educational programs, and scientific exchange activities.

Partner with medical affairs, commercial, and marketing teams to develop scientifically accurate and clinically meaningful educational content.

Lead publication planning and support development of manuscripts, abstracts, presentations, congress submissions, and peer-reviewed publications.

Maintain scientific rigor and ensure evidence is effectively communicated to diverse clinical, scientific, and payer audiences.

People Leadership

Lead, mentor, and develop a team of medical directors and disease-specific clinical leaders supporting the MRD portfolio.

Provide strategic oversight across disease-specific clinical development programs and evidence-generation plans.

Establish portfolio priorities, allocate resources, and align development objectives with organizational goals and business strategy.

  • Foster a culture of scientific excellence, innovation, accountability, and cross-functional collaboration.
  • Develop talent and organizational capabilities that support continued growth of Labcorp Oncology's MRD and precision oncology programs.

Cross-Functional Leadership

  • Collaborate closely with medical affairs, operations, biostatistics, regulatory affairs, market access, legal, compliance, commercial, and R&D teams.
  • Support regulatory submissions and interactions by providing clinical expertise and scientific rationale.

Partner with commercial leadership to ensure clinical evidence supports successful product launches and growth initiatives.

Monitor emerging scientific, clinical, and competitive developments in oncology, molecular diagnostics, and liquid biopsy technologies to inform strategy and decision-making.

Minimum Qualifications

M.D. or D.O. degree from an accredited medical school.

  • Board certification in Medical Oncology.
  • 5 or more years of post-fellowship clinical experience treating patients with solid tumors.

3 or more years of oncology clinical development, clinical research, clinical trial leadership, or evidence-generation experience within the pharmaceutical, biotechnology, diagnostics, CRO, or academic research environment.

8 or more years of experience designing, leading, or supporting prospective and/or retrospective clinical studies, including protoc

Key Responsibilities

The Medical Director will lead the clinical development strategy for the MRD portfolio across solid tumors, overseeing evidence generation and product adoption. They will manage a team of clinical leaders and collaborate with cross-functional partners to integrate MRD testing into routine oncology practice.

Requirements

Candidates must hold an M.D. or D.O. degree with board certification in Medical Oncology and at least 8 years of experience in clinical study design and leadership. A strong background in oncology clinical development, molecular diagnostics, and cross-functional team management is required.

Qualifications

Education
Professional certificate or licensure
Experience
10+ years of experience

Key Skills

Clinical trial designStrategic leadership

Medical Affairs — Physician Career Context

The cost-of-living index for North Carolina is 94.3 (US average = 100; BEA Regional Price Parities (2024)). 59.2% of North Carolina clinicians report burnout symptoms in WeekdayDoc's Burnout Index (2026-01 data).

Lab holds silver-tier status on WeekdayDoc's Top Employers work-life index, composite score 76/100, 13 active listings.

Medical Affairs pay on WeekdayDoc is down 1.7% vs. the prior quarter (through Sep 2026).

Work-Life Balance Analysis

WeekdayDoc's proprietary algorithm rates Oncologist, Medical Director, Clinical Development - MRD at Lab a 8.0 out of 10 for work-life balance — classified as excellent. This places the position in the top 5% in Medical Affairs — ranked against 263 active Medical Affairs listings on WeekdayDoc. Contributing factors include no weekend requirements, no night shifts.

Top Medical Affairs Jobs

1 matches · ranked by pay
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Work-life snapshot

median 4.2this job 8.0
Among the best 10% of Medical Affairs listings for work-life

Listing-based score, 0–10, across 263 comparable listings. Shaded area = the share scoring below this one.

  • No weekends
  • No nights

Living in Durham

Typical 3-bedroom home value
$363k
Typical market rent
$1,659/mo
Residents’ average commute
22 min
Metro price indexU.S. average = 100
97.6
State income tax
Up to 4.8%
Sources & methodology

Sources: Zillow home values (Aug 2026), Zillow market rents (Aug 2026), U.S. Census ACS 2024 five-year.

BEA 2024 · Durham-Chapel Hill, NC metro prices. Housing figures are city-level.

City-level figures. Not a cost-of-living guarantee.

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About Lab

Medical Practices
Burlington, North Carolina
11-50 employees

Benefits & Perks

Medical, Dental, Vision, Life, STD/LTD, 401(k), Paid Time Off (PTO) or Flexible Time Off (FTO), Tuition Reimbursement and Employee Stock Purchase Plan