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MUSC
Charleston, South Carolina

Nurse Practitioner or Physician Assistant - Hematology Oncology

Nurse PractitionerNo weekendsFull-Time Physician-Supervised State

Compensation

Pay not listed

The week · per this posting · Monday – Thursday

Ask the employer about the pay range, call expectations, nights and shift pattern and time off.

Posted 52m ago · Verified live

Job Description

Job Description Summary

The successful applicant will be an Advanced Practice Provider interested in working full-time in the care of patients with cancer- specifically those enrolled in clinical trials for oncology treatment.

The APP will join a growing oncology clinical research program at the Hollings Cancer Center, actively participate in the Phase I Disease Focus Group and collaborate regularly with the HCC Clinical Trials Office.

This position will support the early phase research infusion suite, participate in the feasibility review of new study opportunities, and provide care for patients participating in trials in the outpatient clinic setting as well as inpatient units.

The Hollings Cancer Center is the only NCI Designated Cancer Center in the state, and the Clinical Trials Office supports approximately 200 active studies at a given time.

  • Entity
  • University Medical Associates (UMA) Only Employees and Financials
  • Worker Type
  • Employee
  • Worker Sub-Type
  • Regular
  • Cost Center
  • CC000970 COM DOM Hematology/Oncology CC
  • Pay Rate Type

Salary

  • Pay Grade
  • Health-33
  • Scheduled Weekly Hours
  • 40

Work Shift

Day (United States of America)

Job Description

Fair Labor Standards Act Status: Salaried/Exempt

Hours per week: 40hrs

Scheduled Work Hours/Shift: Monday – Thursday, 8am-6pm. Occasional variation in shift schedule for inpatient rounds on admitted trial patients.

  • Patient Population Focus-Adult Hematology Oncology
  • Inpatient- ART 7E, ART 7W, Main 7W, primarily
  • Outpatient- Hollings Cancer Center- HCC3 Clinic, primarily
  • Infusion Suite- Hollings Cancer Center-HCC3 Infusion primarily

Patient Population Age Range

13 years-death

Required Minimum APP Training

Completion of an accredited Physician Assistant program and currently licensed or eligible for licensure as a Physician Assistant or;

Completion of an accredited Nurse Practitioner Program and currently licensed or eligible for licensure as an APRN as noted below.

AGPNP/ANP (Adult Gerontology Primary Care NP or Adult NP): Adult pts (13 years to death), stable chronic disease state management or primary care setting.

FNP (Family NP): (birth to death) Stable chronic disease state management, primary care across the lifespan.

Preferred APRN Training

AGACNP/ACNP (Adult Gerontology Acute Care NP/Acute Care Nurse Practitioner): Adult pts (13 years to death), acutely ill or injured, potentially unstable, or technologically dependent (vents, drips, monitors, etc.)

Required Minimum APP Experience: Oncology experience

Preferred APP Experience - Minimum of 2 years’ experience in Oncology as a PA or APRN. Experience in Oncology Research or as a Study Coordinator.

Degree of Supervision

Advanced Practice Registered Nurse or Physician Assistant will be assigned a Primary Supervising/Collaborating Supervision under APP Manager for Division of Hematology Oncology.

  • Required Licensure, Certifications, Registrations
  • All certifications must be current and complete prior to start date:
  • Specialty Board Certification – PA, APRN
  • Oncology Specialty Certification – preferred (to meet Comprehensive Cancer Center Status)
  • Basic Life Support (BLS).
  • Advanced Cardiovascular Life Support (ACLS)
  • DHEC and DEA license applications must be started prior to first day.

Job Duties

Provides direct care to patients through the following activities:

Takes comprehensive history and performs physical examinations and ensures detailed documentation is entered in a timely manner.

Serves as provider coverage for the outpatient research infusion suite; responds to infusion related reactions, assesses toxicities of treatment, provides research drug education.

Conducts assessments and physical exams on hospitalized clinical trial patients in accordance with good clinical practice and the appropriate research protocol.

Evaluates and treats per research protocol and using clinical judgement on the basis of history, physical examination, radiological, laboratory, and other diagnostic test results pursuant to the practice agreement or scope of practice guidelines.

Adheres to Good Clinical Practice guidelines and has a comprehensive understanding of the Informed Consent process (what it entails, the regulations, and required documentation)

Initiates referrals to other health care providers, and/or consults with the attending physician, the collaborating physician and the local study Principal Investigator.

  • Documents and bills for direct care provided and has a general understanding of research billing requirements.
  • Utilizes current research and evidence-based decision-making in all clinical practice.
  • Performs and participates in quality/performance improvement activities and promotes clinical research participation.
  • Participates in and supports accreditation, compliance, and regulatory activities of the organization.

Demonstrates responsibility for professional practice through active participation in professional organizations and continuing education

APRN or PA must maintain licenses, certifications, CNEs/CMEs, etc. as required by applicable policies and state law

Completes all MUSC required research onboarding and ongoing training, and maintains a valid CTEP ID within the NCI Database

Participates in the Phase 1 Disease Focus Group: attends weekly interdisciplinary meetings, evaluates new study concepts and helps implement new research workflows within the Hollings Cancer Center.

Registers with the MUSC eIRB and serves as a Co-I on all Phase 1 studies.

Triages research patient calls in collaboration with CTO Research Nurse Managers and Physician investigators; prescribes supportive care for patients receiving treatment on studies per protocol guidelines.

Provides initial review of Adverse Event grading per CTCAE and assigns attribution and causality with confirmation from supervising Physician.

Additional Job Description

Physical Requirements

Continuous requirements are to perform job functions while standing, walking and sitting. Ability to bend at the waist, kneel, climb stairs, reach in all directions, fully use both hands and legs, possess good finger dexterity, perform repetitive motions with hands/wrists/elbows and shoulders, reach in all directions.

Ability to be qualified physically for respirator use, initially and as required. Maintain 20/40 vision corrected, see and recognize objects close at hand and at a distance, work in a latex safe environment and work indoors.

Frequently lift, lower, push and pull and/or carry objects weighing 50 lbs (+/-) unassisted, exert up to 50 lbs of force, lift from 36" to overhead 25 lbs. Infrequently work in dusty areas and confined/cramped spaces.

If you like working with energetic enthusiastic individuals, you will enjoy your career with us!

The Medical University of South Carolina is an Equal Opportunity Employer.

MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations.

All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need.

Medical University of South Carolina participates in the federal E-Verify program to confirm the identity and employment authorization of all newly hired employees. For further information about the E-Verify program, please click here: uscis.gov

Key Responsibilities

The Advanced Practice Provider will provide direct clinical care to oncology patients enrolled in clinical trials, including conducting physical exams and managing infusion treatments. They will also collaborate with the clinical research team to implement study protocols, monitor patient safety, and ensure regulatory compliance.

Requirements

Candidates must have completed an accredited Physician Assistant or Nurse Practitioner program and hold or be eligible for relevant state licensure. A minimum of two years of oncology experience is preferred, along with current BLS and ACLS certifications.

Qualifications

Education
Professional certificate or licensure
Experience
2+ years of experience

Key Skills

Patient careInfusion therapyEvidence-based practiceQuality improvementTriage

Oncology — Nurse Practitioner Career Context

Of the 50 active Nurse Practitioner listings this role was benchmarked against, 18% are remote, 54% have no call, 66% require no weekends.

The cost-of-living index for South Carolina is 93.7 (US average = 100; BEA Regional Price Parities (2024)). 60.6% of South Carolina clinicians report burnout symptoms in WeekdayDoc's Burnout Index (2026-01 data).

What does the Nurse Practitioner market look like in South Carolina?
MeasureThis jobMarket
Listed paynot listedNurse Practitioner median $139k (middle half $130k–$159k)289 comparable listings, Oct 2026
Cost of livingSouth Carolina index 93.7US average = 100BEA Regional Price Parities (2024)
Nurse Practitioner listings in South Carolina304 active14,248 nationallylive on WeekdayDoc, Oct 2026
Work settingon-sitepeers: 18% remote · 54% no call · 66% no weekends50 benchmarked listings
Nurse Practitioner pay trend+1.1% vs prior quarter—through Sep 2026
Sources: WeekdayDoc live listing index, BEA Regional Price Parities (2024); as of Oct 2026. Same values as the Weekday Verdict and Market Insights on this page.

Top Nurse Practitioner Jobs

29 matches · ranked by pay

Salary Distribution

26 jobs · 23 employers
6
<$125k
5
$125k-150k
12
$150k-175k
3
$175k-200k

Annual compensation range

Benefits & Perks

18 jobs
401k / retirement match
94%
Sign-on bonus
67%
CME allowance
67% this job
Loan repayment
17%
Relocation assistance
6%

Share of similar jobs offering each benefit

#1

FNP needed for interim coverage - Dec - MarchContract

Georgia Medical Staffing · Glen Allen, Virginia

$90 per hour
#2

Nurse Practitioner

White Plains Hospital · Claremont, New Hampshire

$145k-$185k
#3

Occupation Health Nurse Practitioner (Full-Time)

$143k-$182k
#4

Nurse Practitioner - Virtual Sleep - Full Time

$54.9-$82.35/hr
+ 27 more · ranked by pay

Work-life snapshot

median 5.1this job 3.9
Better work-life than 30% of Oncology (NP) listings

Listing-based score, 0–10, across 291 comparable listings. Shaded area = the share scoring below this one.

  • No weekends
  • On-site
MUSC logo

About MUSC

Hospitals and Health Care
Charleston, South Carolina
5,001-10,000 employees

Benefits & Perks

Health insurance
Professional development
Continuing education

Living in Charleston

Typical 3-bedroom home value
$530k
Typical market rent
$2,288/mo
Residents’ average commute
24 min
Metro price indexU.S. average = 100
101.0
State income tax
Up to 6.5%
Sources & methodology

Sources: Zillow home values (Sep 2026), Zillow market rents (Sep 2026), U.S. Census ACS 2024 five-year.

BEA 2024 · Charleston-North Charleston, SC metro prices. Housing figures are city-level.

City-level figures. Not a cost-of-living guarantee.