City of Hope logo
City of Hope
Irvine, California

Physician | Infectious Diseases | Irvine, CA

Infectious DiseaseFull-Time

Listed compensation

$210K - $224K

The week · per this posting · weekdays assumed

Ask the employer about the work setting, call expectations, weekend coverage and time off.

Posted 2mo ago

Job Description

Physician | Infectious Disease | Irvine, CA

City of Hope Medical Group seeks an Infectious Disease Physician to provide services for our Irvine campus, joining our two full-time Infectious Disease faculty members at a rapidly expanding, nationally recognized cancer institute.

We seek to hire a full-time clinical faculty member at the Assistant-Associate Professor level who is mission minded and will provide exceptional patient centered care. For more information, please visit here Lennar Foundation Cancer Center (LFCC) and Department of Medicine.

We want our employees to enjoy all aspects of their professional and personal lives. Recognizing the value in diverse perspectives, we have programs that leverage engagement by bringing our professional community together.

In the same way we view patient care from a broad perspective, City of Hope encourages its employees, too, to enhance their view, by increasing their knowledge continually. Here at City of Hope, you will find great opportunities to provide fulfilling service, and to enjoy workplace satisfaction.

Highlights

  • Coverage at only one location: hospital is located on campus
  • State-of-the-art facilities: 73 bed hospital, 4 operating room suites, 8 bed ICU

Duties

  • Clinical time is divided between inpatient and outpatient services
  • Contributions to Antimicrobial Stewardship and Infection Control efforts at LFCC
  • Opportunities for clinical research

Pay & Benefits

  • Excellent benefits package, including a generous retirement contribution plan
  • Relocation assistance may be available
  • Base Salary Range: Assistant level: $210K-$215K | Associate level: $215K-$224K

*The salary range listed is exclusively for base compensation for full-time employment and does not include incentive compensation or benefits. Actual compensation will be adjusted for experience, training, hospital/community need and other factors.

Benefits information: City of Hope Medical Group Benefits

Irvine Campus

City of Hope Orange County is transforming cancer care for generations. As an NCI-designated comprehensive cancer center, City of Hope achieves exceptional outcomes difficult to obtain elsewhere. Our cancer center offers access to experts with unparalleled expertise in breast, prostate, lung, blood, gastrointestinal and gynecological cancers, and more.

In 2025, City of Hope opened Orange County’s only specialty cancer hospital. This six-story hospital is seamlessly connected to City of Hope Orange County Lennar Foundation Cancer Center. With the newly opened hospital – City of Hope’s second academic hospital in California – we are fulfilling our promise to Orange County and completing the continuum of care for people with cancer.

The spectacular capstone to our 11-acre City of Hope Orange County campus is the largest new construction dedicated to cancer care in the Western United States. Where other hospitals must serve the full spectrum of health conditions in our community, every team member at this specialty cancer hospital—from the nurses to nutritionists to physicians – will have a core focus on oncology.

M.D. or D.O. from an accredited educational institution

Board Certified/eligible in Infectious Diseases

*Experience in transplant infectious disease or 1-2 years working within hematologic malignancies *preferred but not required

Possession of, or eligibility for, unrestricted medical license in the State of California

Key Responsibilities

The physician will provide inpatient and outpatient infectious disease services at the Irvine campus. They will also contribute to antimicrobial stewardship and infection control efforts while participating in clinical research.

Requirements

Candidates must hold an M.D. or D.O. degree and be board certified or eligible in Infectious Diseases. Possession of or eligibility for an unrestricted medical license in California is required.

Qualifications

Experience
2+ years of experience

Certifications

Board Certification

Work-Life Balance Analysis

WeekdayDoc's proprietary algorithm rates Physician | Infectious Diseases | Irvine, CA at City of Hope a 6.6 out of 10 for work-life balance — classified as good. This places the position in the Above average in Physician roles — ranked against 21,509 active Physician roles listings on WeekdayDoc.

Infectious Disease — Physician Career Context

The cost-of-living index for California is 110.7 (US average = 100; BEA Regional Price Parities (2024)), so the posted ~$217k midpoint carries the purchasing power of roughly $196k in an average-cost state. 63.6% of California clinicians report burnout symptoms in WeekdayDoc's Burnout Index (2026-01 data).

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Salary Distribution14 jobs · 2 employers

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Annual compensation range

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Work-life snapshot

median 6.6this job 6.6
Better work-life than 50% of Infectious Disease listings

Listing-based score, 0–10, across 164 comparable listings. Shaded area = the share scoring below this one.

Living in Irvine

Typical 3-bedroom home value
$1.36M≈ 6.5× annual pay
Typical market rent
$3,527/mo≈ 20% of gross pay
Residents’ average commute
25 min
Metro price indexU.S. average = 100
113.6
State income tax
Up to 13.3%
Sources & methodology

Sources: Zillow home values (Aug 2026), Zillow market rents (Aug 2026), U.S. Census ACS 2024 five-year.

BEA 2024 · Los Angeles-Long Beach-Anaheim, CA metro prices. Housing figures are city-level.

Ratios use this listing’s gross annual pay. Not a cost-of-living guarantee.

City of Hope logo

About City of Hope

Hospitals and Health Care
Duarte, CA
10,000+ employees

Benefits & Perks

Excellent benefits package
Generous retirement contribution plan
Relocation assistance
Health insurance
Dental insurance
Vision insurance