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Dompé
San Mateo, California

Senior Medical Director, Medical Affairs

Medical AffairsFull-Time

Listed compensation

Base Salary: $290K–$300K

The week · per this posting

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Posted 1mo ago · Verified live

Job Description

Dompé is an Italian bio-pharmaceutical company that focuses on innovation, where a long tradition in the field of personal wellness goes hand-in-hand with a commitment to research and development to meet unsatisfied therapeutic needs.

Established in 1940 in Milan, Dompé has an industrial and biotech research hub in L’Aquila, in addition to branches in Europe (Barcelona, Berlin, Paris and Tirana). The company has approximately 900 employees. The US headquarters of Dompé are based in Boston (R&D) and in the San Francisco Bay Area (Commercial Operations).

Job Summary

The Senior Medical Director sets the overarching strategy and governance framework for how Medical Affairs engages internal and external stakeholders, including HCPs, KOLs, professional societies, and advocacy groups.

This individual ensures KOL engagement activities across Field Medical Affairs, Medical Communications, Patient Advocacy, and R&D are coordinated, compliant, and aligned to a unified medical narrative. The Senior Medical Director provides senior medical/scientific leadership on priority stakeholder relationships.

Job Description

External Representation at the Portfolio Level

  • Act as the senior medical representative of Dompé in cross-indication external forums — major congresses, professional society leadership meetings, and multi-stakeholder coalitions — where portfolio-wide scientific credibility matters more than any single asset
  • Build and maintain relationships with external bodies that don't map to a single indication (e. g., regulatory science forums, guideline committees, patient coalition umbrella groups), representing Dompé's overall medical position
  • Serve as the escalation point when external stakeholders raise cross-portfolio questions, ensuring a unified response rather than separate answers from individual Indication Leads
  • Partner with cross-functional teams to ensure external medical messaging is consistent with Dompé's broader scientific reputation and positioning

Engagement Strategy and Governance

  • Define the enterprise-wide medical engagement strategy and stakeholder mapping framework
  • Establish governance standards for KOL engagement, advisory boards, and scientific exchange
  • Ensure all engagement activities meet compliance, legal, and regulatory standards

Stakeholder Leadership

  • Provide medical/scientific leadership on key strategic insitituions and build relationships with priority portfolio level Key Opnion Leaders
  • Partner with Field Medical Affairs, Medical Communications, Patient Advocacy, and R&D to ensure coordinated execution
  • Advise senior leadership on engagement strategy risks, opportunities, and emerging stakeholder needs
  • Serve as a senior medical voice in relationships with professional societies and guideline committees

Insight Capture and Strategic Feedback Loop

  • Establish a consistent process for capturing engagement insights (from advisory boards, KOL interactions, and scientific exchange) and feeding them into evidence generation and communications planning
  • Report engagement trends and stakeholder sentiment to the Medical Affairs Leadership Team and broader leadership teams on a regular cadence
  • Identify emerging scientific or competitive themes surfaced through engagement and flag implications for medical strategy

Qualifications

Required

  • MD, PharmD, PhD, or equivalent advanced clinical/scientific degree
  • 8+ years in medical affairs, with direct experience in stakeholder or KOL engagement
  • Strong understanding of compliance frameworks governing HCP interactions
  • Demonstrated strategic planning and cross-functional leadership experience
  • Excellent communication and relationship-building skills with external experts

Preferred

  • Prior experience in a field medical or medical director role
  • Experience across multiple regions or countries
  • Track record designing engagement governance frameworks

Competencies

  • Strategic governance: builds frameworks that keep engagement activity coordinated and compliant across functions
  • Stakeholder credibility: earns the trust of KOLs and external experts through scientific depth and reliability
  • Cross-functional orchestration: aligns Field Medical, Medical Communications, and Patient Advocacy around a shared engagement plan
  • Risk judgment: identifies compliance and reputational risks in engagement activity before they materialize
  • Mentorship: develops the judgment and scientific confidence of more junior medical directors

Benefits of Joining Our Team

  • Comprehensive medical benefits: we value access to healthcare for our patients as well as our employees
  • Generous vacation / holiday time off: we care about our employees and encourage a balanced lifestyle
  • Competitive 401(K) matching

Base Salary: $290,000 -$300,000 a year

At Dompe, we offer an attractive compensation package to our team members. Any offer would include a competitive base salary (estimate shared above), incentive bonus, and benefits package customary to the position. Actual individual pay is determined based on experience, qualifications, geographic location, and other job-related factors permitted by law.

We believe that the unique contributions of all employees create our success. To ensure that our products and culture continue to incorporate everyone’s perspectives and experience, we never discriminate based on race, religion, national origin, gender identity or expression, sexual orientation, age, or marital, veteran, or disability status. All your information will be kept confidential according to EEO guidelines.

Key Responsibilities

The Senior Medical Director defines the enterprise-wide medical engagement strategy and governance framework to ensure coordinated stakeholder interactions. They serve as the senior medical representative in cross-indication forums and provide scientific leadership to align internal teams with external medical narratives.

Qualifications

Education
Doctoral or professional degree (postgraduate degree)
Experience
10+ years of experience

Key Skills

Stakeholder engagementKOL managementCommunication skills

Work-Life Balance Analysis

WeekdayDoc's proprietary algorithm rates Senior Medical Director, Medical Affairs at Dompé a 6.6 out of 10 for work-life balance — classified as good. This places the position in the Above average in Medical Affairs — ranked against 212 active Medical Affairs listings on WeekdayDoc.

Medical Affairs — Physician Career Context

The cost-of-living index for California is 110.7 (US average = 100; BEA Regional Price Parities (2024)), so the posted ~$295k midpoint carries the purchasing power of roughly $266k in an average-cost state. 63.6% of California clinicians report burnout symptoms in WeekdayDoc's Burnout Index (2026-01 data).

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1 matches · ranked by pay
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Work-life snapshot

median 4.3this job 6.6
Better work-life than 70% of Medical Affairs listings

Listing-based score, 0–10, across 212 comparable listings. Shaded area = the share scoring below this one.

Living in San Mateo

Typical 3-bedroom home value
$1.81M≈ 6.2× annual pay
Typical market rent
$3,917/mo≈ 16% of gross pay
Residents’ average commute
26 min
State income tax
Up to 13.3%
Sources & methodology

Sources: Zillow home values (Aug 2026), Zillow market rents (Aug 2026), U.S. Census ACS 2024 five-year.

Ratios use this listing’s gross annual pay. Not a cost-of-living guarantee.

Dompé logo

About Dompé

Pharmaceutical Manufacturing
Milano, Lombardia
1,001-5,000 employees

Benefits & Perks

Comprehensive medical benefits
Generous vacation / holiday time off
Competitive 401(K) matching
Incentive bonus