259+ Nurse Practitioner Jobs in Missouri
Nurse Practitioner positions in Missouri with $100K-$150K salary ranges, burnout scores, and schedule details shown upfront. Filter by no call, remote, and weekday-only.
259+ positions available
259+ Nurse Practitioner Jobs in Missouri Available Now
These 139 roles pay ~$168k median with 6.4/10 median work-life balance — use these as your benchmarks.
Psychiatric Mental Health Nurse Practitioner (PMHNP) / Physician Assistant - Outpatient
Washington University in St. Louis
in Psychiatry (NP)
in Primary Care (NP)
Nurse Practitioner or Physician Assistant - F/T - Hazelwood Florissant Internal Medicine
Esse HealthGreat Workplace
in Internal Medicine (NP)
Nurse Practitioner - 3 Days - South County/Tesson Ferry
Esse HealthGreat Workplace
in Primary Care (NP)
Care Manager - Nurse Practitioner - PRN
Esse HealthGreat Workplace
in Nurse Practitioner roles
Nurse Practitioner - F/T - Watson Primary Care
Esse HealthGreat Workplace
in Primary Care (NP)
Nurse Practitioner - F/T - Watson Primary Care
Esse HealthGreat Workplace
in Primary Care (NP)
Nurse Practitioner or Physician Assistant - P/T or F/T - Fenton Family Medicine
Esse HealthGreat Workplace
in Family Medicine (NP)
in Family Medicine (NP)
Nurse Practitioner - P/T or F/T - South County - Gastroenterology
Esse HealthGreat Workplace
in Gastroenterology (NP)
$5,000 Signing Bonus - Full-time Nurse Practitioner - St. Joseph, MO (76272)
Centurion Health
in Correctional Medicine (NP)
Nurse Practitioner (PRN) - In-Home Health Assessments
Matrix Medical NetworkGreat Workplace
in Geriatrics (NP)
in Family Medicine (NP)
Field Nurse Practitioner - Saint Charles County, Missouri
AdvantmedGreat Workplace
in Family Medicine (NP)
Nurse Practitioner or Physician Assistant - Nutritional Science
Washington University in St. Louis
in Nurse Practitioner roles
A nurse practitioner in missouri role paying $125/visit is hidden in this list.
258 more hidden below, ranked by pay and work-life.
Nurse Practitioner - Hospice
One-time payment · dashboard + negotiation brief on every application
2 more roles in this search — preview locked listings
How Missouri Compares for Nurse Practitioner Pay
Missouri against neighboring states and the top payers, from our own nurse practitioner postings over the last 12 months — not a salary survey.
Nurse Practitioner roles in Missouri advertise $5k below the $136k median across the 51 states we can measure, where New Hampshire leads at $170k.
| State | Median pay | vs MO | WLB | Listings |
|---|---|---|---|---|
| Missouri (this page) | $131k | — | 5.9/10 | 616 |
| Illinoisborders | $140k | +$9k | 5.1/10 | 1333 |
| Kansasborders | $135k | +$4k | 5.9/10 | 229 |
| Arkansasborders | $130k | −$1k | 5.8/10 | 230 |
| Oklahomaborders | $128k | −$3k | 5.4/10 | 279 |
| Nebraskaborders | $126k | −$5k | 5.4/10 | 160 |
| Kentuckyborders | $126k | −$5k | 5.8/10 | 275 |
| Iowaborders | $122k | −$9k | 5.5/10 | 339 |
“borders” = shares a border with Missouri; “#n” = national pay rank among the 51 measured states.
Missouri Jobs
259+ nurse practitioner positions in Missouri
Competitive Pay
Earn $100K-$150K with benefits
Updated Daily
New positions added daily
Nurse Practitioner Jobs in Missouri: Salary, Outlook & Work-Life Balance
Missouri offers a competitive market for healthcare professionals seeking nurse practitioner jobs in missouri. With 259+ open positions and salaries ranging from $50K to $300K, clinicians have strong options for career growth and work-life balance.
Every listing is evaluated using WeekdayDoc's proprietary work-life balance scoring system. Nurse Practitioner Jobs in Missouri on this page have an average score of 7.9/10, with 25% with no on-call requirements, 65% with no weekends, 10% offering remote work. This data helps clinicians quickly identify positions that match their lifestyle priorities without reading through hundreds of job descriptions.
Leading employers currently hiring for nurse practitioner jobs in missouri include Esse Health, CoxHealth, Washington University in St. Louis, UnitedHealth Group, and more. Positions span nurse practitioner jobs missouri. New jobs are added daily as healthcare organizations expand their teams.
Among the top-rated employers hiring for nurse practitioner jobs in missouri, Sailor Health (score: 97.0/100), GLOBAL OUTREACH TELEREHABILITATION (score: 96.8/100), Talkiatry (score: 96.4/100) have earned WeekdayDoc's Top Employer designation based on our proprietary ranking system. This ranking evaluates burnout scores (40%), salary competitiveness (30%), and work-life balance features like no-call and remote options (30%). See the full rankings on our Top Employers page.
According to WeekdayDoc's Market Pulse — which tracks real-time compensation data from thousands of active job postings — the current median salary is $107K, trending up 1.3% over the past quarter. This data is derived from 79,590+ job postings analyzed over the past 12 months — updated daily, unlike annual survey-based reports. Explore salary trends and burnout data on our Market Pulse dashboard.
Frequently Asked Questions
How much do nurse practitioners earn in Missouri?
Listed nurse practitioners in Missouri on WeekdayDoc pay roughly $50K to $300K per year, with a median near $95K. Actual pay varies by specialty, setting, experience, and shift type — every listing shows its salary upfront.
Are there remote or hybrid nurse practitioners jobs available?
Yes — about 10% of current nurse practitioners listings offer remote or hybrid work. You can filter for telehealth and work-from-home options, and every listing shows its remote status before you apply.
Which nurse practitioners jobs have the best work-life balance?
Every nurse practitioner role on WeekdayDoc is scored for burnout risk using call schedule, weekend and night requirements, and remote flexibility. Among current listings, 25% with no on-call and 65% with no weekends. You can sort by work-life-balance score to surface the lowest-burnout roles first.
Who is hiring nurse practitioners in Missouri right now?
Employers currently hiring for nurse practitioner roles include Esse Health, CoxHealth, Washington University in St. Louis, UnitedHealth Group, and others. WeekdayDoc aggregates verified openings from these and other organizations, refreshed daily.
How many nurse practitioner jobs in missouri are available, and how often are they updated?
There are currently 259+ nurse practitioners positions in Missouri listed, with new roles added daily as employers post them. Create a free account to compare salaries and work-life-balance scores side by side, then apply directly.
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