Nurse Practitioner Jobs in Missouri
Across 317 live Nurse Practitioner listings in Missouri, median advertised pay is $164K (75th percentile $175K), based on the 118 that state a salary; Missouri ranks 43rd of 51 states by median advertised pay; the employers with the most openings are CVS Health (40), Centurion Health (28), Washington University in St. Louis (25).
317+ positions available
Figures are computed from live listings and reviewed by WeekdayDoc’s physician-led editorial team; data as of October 16, 2026. Posted ranges, not accepted offers. How we compute this
317+ Nurse Practitioner Jobs in Missouri Available Now
These 118 roles pay ~$164k median with 6.6/10 median work-life balance — use these as your benchmarks.
In-Home Nurse Practitioner Per Diem - Saint Louis, MO
In-Home Nurse Practitioner Part Time - West Plains
In-Home Nurse Practitioner Part Time - Quincy, MO
In-Home Nurse Practitioner Full Time - Jefferson City
In-Home Nurse Practitioner Per Diem - Maryville
In-Home Nurse Practitioner Per Diem - Quincy, MO
In-Home Nurse Practitioner Part Time - Jefferson City
In-Home Nurse Practitioner Part Time - Kansas City, MO
In-Home Nurse Practitioner Full Time - Cape Girardeau
In-Home Nurse Practitioner Part Time - Maryville
In-Home Nurse Practitioner Per Diem - Springfield
In-Home Nurse Practitioner Part Time - Saint Louis, MO
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How Missouri Compares for Nurse Practitioner Pay
Missouri against neighboring states and the top payers, from our own nurse practitioner postings over the last 12 months — not a salary survey.
Nurse Practitioner roles in Missouri advertise $6k below the $135k median across the 51 states we can measure, where California leads at $163k.
| State | Median pay | vs MO | WLB | Listings |
|---|---|---|---|---|
| Missouri (this page) | $128k | — | 5.6/10 | 775 |
| Kansasborders | $136k | +$7k | 5.6/10 | 297 |
| Illinoisborders | $135k | +$7k | 5.4/10 | 1597 |
| Oklahomaborders | $129k | +$1k | 5.1/10 | 358 |
| Arkansasborders | $126k | −$3k | 5.1/10 | 383 |
| Iowaborders | $125k | −$3k | 5.2/10 | 447 |
| Kentuckyborders | $125k | −$3k | 5.3/10 | 408 |
| Nebraskaborders | $122k | −$6k | 5.3/10 | 187 |
“borders” = shares a border with Missouri; “#n” = national pay rank among the 51 measured states.
Nurse Practitioner Jobs in Missouri: Market Overview & Work-Life Balance
Listing snapshot: this overview summarizes the jobs loaded on this page. Market comparisons use the separate scope and time period labeled in their section.
Missouri offers a competitive market for healthcare professionals seeking nurse practitioner jobs in missouri. With 317+ open positions, clinicians have strong options for career growth and work-life balance.
Every listing is evaluated using WeekdayDoc's proprietary work-life balance scoring system. Nurse Practitioner Jobs in Missouri on this page have an average score of 4.5/10. This data helps clinicians quickly identify positions that match their lifestyle priorities without reading through hundreds of job descriptions.
Leading employers currently hiring for nurse practitioner jobs in missouri include CVS Health, Freeman Health System. Positions span nurse practitioner jobs missouri. New jobs are added daily as healthcare organizations expand their teams.
Among the top-rated employers hiring for nurse practitioner jobs in missouri, BetterHelp (score: 95.9/100), Talkiatry (score: 95.0/100), Hiaah (score: 94.5/100) have earned WeekdayDoc's Top Employer designation based on our proprietary ranking system. This ranking evaluates burnout scores (40%), salary competitiveness (30%), and work-life balance features like no-call and remote options (30%). See the full rankings on our Top Employers page.
According to WeekdayDoc's Market Pulse — which tracks real-time compensation data from thousands of active job postings — the current median salary is $106K, trending up 3.9% over the past quarter. This data is derived from 32,313+ job postings analyzed over the past 12 months — updated daily, unlike annual survey-based reports. Explore salary trends and burnout data on our Market Pulse dashboard.
A few things worth knowing
About Nurse Practitioner jobs in Missouri.
How much do nurse practitioners earn in Missouri?
A reliable salary estimate is unavailable for this sample of nurse practitioners. Compensation varies by role, specialty, location, and schedule. Compare employer-posted pay where disclosed, including its currency and pay period; missing pay is not estimated.
Are there remote or hybrid nurse practitioners jobs available?
Some nurse practitioners roles offer remote or hybrid flexibility. You can filter for telehealth and work-from-home options, and every listing shows its remote status before you apply.
Which nurse practitioners jobs have the best work-life balance?
Every nurse practitioner role on WeekdayDoc is scored for burnout risk using call schedule, weekend and night requirements, and remote flexibility. You can sort by work-life-balance score to surface the lowest-burnout roles first.
Who is hiring nurse practitioners in Missouri right now?
Employers currently hiring for nurse practitioner roles include CVS Health, Freeman Health System. WeekdayDoc aggregates verified openings from these and other organizations, refreshed daily.
How many nurse practitioner jobs in missouri are available, and how often are they updated?
There are currently 317 nurse practitioners positions in Missouri listed, with new roles added as employers post them. Job descriptions are public. Verified sign-in with Google or email gives free access to regular Apply, full search, and standard Market Insights. Saved jobs, My Search, and the dashboard also require verified sign-in. Eligible featured employer listings allow Apply without signup or email. Basic calculators are public and free; optional AI contract analysis, RVU Billing Optimizer, and Schedule Optimizer reports remain paid.
Employers hiring now
Organizations with the most openings in Nurse Practitioner Jobs in Missouri
CVS Health40 open roles here · WLB 61/100
Centurion Health28 open roles here · WLB 71/100
Washington University in St. Louis25 open roles here · WLB 67/100
BJC HealthCare22 open roles here · WLB 52/100
Esse Health17 open roles here · WLB 61/100UnitedHealth Group17 open roles here · WLB 70/100
CoxHealth13 open roles here · WLB 66/100
GoHealth Urgent Care7 open roles here · WLB 68/100