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Nurse Practitioner Jobs in Missouri

Across 316 live Nurse Practitioner listings in Missouri, median advertised pay is $164K (75th percentile $175K), based on the 118 that state a salary; Missouri ranks 43rd of 51 states by median advertised pay; the employers with the most openings are CVS Health (40), Centurion Health (28), Washington University in St. Louis (25).

316+ positions available

Figures are computed from live listings and reviewed by WeekdayDoc’s physician-led editorial team; data as of October 16, 2026. Posted ranges, not accepted offers. How we compute this

316+ Nurse Practitioner Jobs in Missouri Available Now

Prioritize:

316 jobs

These 118 roles pay ~$164k median with 6.6/10 median work-life balance — use these as your benchmarks.

Salary Distribution118 jobs · 34 employers

19
<$130k
19
$130k-150k
47
$150k-170k
29
$170k-190k
4
$190k+

Annual compensation range

Work-Life Balance Distribution118 jobs · 34 employers

7
1-2
17
3-4
21
5-6
55
7-8
18
9-10

Higher = better work-life balance

GoHealth Urgent Care logo

Physician Assistant — Sign On Bonus $15,000

GoHealth Urgent CareSpringfield, MO

Nurse Practitioner
Pay not disclosed
2m ago
New
Confidential Employer logo

KCOM - Family Medicine Nurse Practitioner

Confidential EmployerKirksville, MO

Nurse Practitioner
Pay not disclosed
12h ago
New
Elara Caring logo

Nurse Practitioner

Elara CaringDexter, MO

Nurse Practitioner
Pay not disclosed
13h ago
New
GoHealth Urgent Care logo

Physician Assistant or Nurse Practitioner- Springfield Region - $15k Sign-On Bonus

GoHealth Urgent CareSpringfield, MO

Nurse Practitioner
Pay not disclosed
Yesterday
New
Swope Health logo

Nurse Practitioner/ Physician Assistant- Float (Family Medicine)

Swope HealthKansas City, MO

Nurse Practitioner
Pay not disclosed
Yesterday
New
Swope Health logo

Pediatric Nurse Practitioner/'Physician Assistant

Swope HealthKansas City, MO

Nurse Practitioner
Pay not disclosed
Yesterday
New
Children's Mercy KC logo

Pediatric Nurse Practitioner | Anesthesia Pain Service

Children's Mercy KCKansas City, MO

Nurse Practitioner
Pay not disclosed
2d ago
GoHealth Urgent Care logo

Physician Assistant or Nurse Practitioner - Sign on Bonus $15,000

GoHealth Urgent CareChesterfield, MO

Nurse Practitioner
Pay not disclosed
3d ago
CVS Health logo

Nurse Practitioner

CVS HealthCreve Coeur, MO

Nurse Practitioner
$41.85-$90.13 per hour
3d ago
CVS Health logo

In-Home Nurse Practitioner Part Time - Cape Girardeau

CVS HealthCape Girardeau, MO

Nurse Practitioner
$37.66-$81.11 per hour
3d ago
New Solutions logo

Nurse Practitioner, SNF

New SolutionsSpringfield, MO

Nurse Practitioner
Pay not disclosed
3d ago
Dover Hospice logo

Hospice Nurse Practitioner

Dover HospiceSaint Louis, MO

Nurse Practitioner
Pay not disclosed
6d ago
CVS Health logo

Nurse Practitioner

CVS HealthEllisville, MO

Nurse Practitioner
$41.85-$90.13 per hour
6d ago
CVS Health logo

Nurse Practitioner

CVS HealthSt. Louis, MO

Nurse Practitioner
$41.85-$90.13 per hour
6d ago
Cardinal Correctional Care logo

Nurse Practitioner

Cardinal Correctional CareRolla, MO

Nurse Practitioner
Pay not disclosed
1w ago
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How Missouri Compares for Nurse Practitioner Pay

Missouri against neighboring states and the top payers, from our own nurse practitioner postings over the last 12 months — not a salary survey.

Median advertised
$128k
Pay rank
#43 of 51
Work-life balance
5.6/10 · #17
Open listings
771

Nurse Practitioner roles in Missouri advertise $6k below the $135k median across the 51 states we can measure, where California leads at $163k.

Nurse Practitioner median pay and work-life-balance score, Missouri compared with neighboring states and the highest-paying states
StateMedian payvs MOWLBListings
Missouri (this page)$128k—5.6/10771
Kansasborders$136k+$7k5.6/10297
Illinoisborders$135k+$6k5.4/101589
Oklahomaborders$129k+$1k5.1/10354
Arkansasborders$126k−$3k5.1/10381
Iowaborders$125k−$3k5.2/10446
Kentuckyborders$125k−$4k5.3/10402
Nebraskaborders$122k−$6k5.2/10184

“borders” = shares a border with Missouri; “#n” = national pay rank among the 51 measured states.

Nurse Practitioner Jobs in Missouri: Market Overview & Work-Life Balance

Listing snapshot: this overview summarizes the jobs loaded on this page. Market comparisons use the separate scope and time period labeled in their section.

Missouri offers a competitive market for healthcare professionals seeking nurse practitioner jobs in missouri. With 316+ open positions, clinicians have strong options for career growth and work-life balance.

Every listing is evaluated using WeekdayDoc's proprietary work-life balance scoring system. Nurse Practitioner Jobs in Missouri on this page have an average score of 3.3/10, with 15% offering remote work. This data helps clinicians quickly identify positions that match their lifestyle priorities without reading through hundreds of job descriptions.

Leading employers currently hiring for nurse practitioner jobs in missouri include CVS Health, GoHealth Urgent Care, Swope Health, Cardinal Correctional Care, and more. Positions span nurse practitioner jobs missouri. New jobs are added daily as healthcare organizations expand their teams.

Among the top-rated employers hiring for nurse practitioner jobs in missouri, BetterHelp (score: 95.9/100), Talkiatry (score: 95.0/100), Hiaah (score: 94.5/100) have earned WeekdayDoc's Top Employer designation based on our proprietary ranking system. This ranking evaluates burnout scores (40%), salary competitiveness (30%), and work-life balance features like no-call and remote options (30%). See the full rankings on our Top Employers page.

According to WeekdayDoc's Market Pulse — which tracks real-time compensation data from thousands of active job postings — the current median salary is $105K, trending up 3.4% over the past quarter. This data is derived from 31,769+ job postings analyzed over the past 12 months — updated daily, unlike annual survey-based reports. Explore salary trends and burnout data on our Market Pulse dashboard.

A few things worth knowing

About Nurse Practitioner jobs in Missouri.

How much do nurse practitioners earn in Missouri?

A reliable salary estimate is unavailable for this sample of nurse practitioners. Compensation varies by role, specialty, location, and schedule. Compare employer-posted pay where disclosed, including its currency and pay period; missing pay is not estimated.

Are there remote or hybrid nurse practitioners jobs available?

Yes — about 15% of current nurse practitioners listings offer remote or hybrid work. You can filter for telehealth and work-from-home options, and every listing shows its remote status before you apply.

Which nurse practitioners jobs have the best work-life balance?

Every nurse practitioner role on WeekdayDoc is scored for burnout risk using call schedule, weekend and night requirements, and remote flexibility. You can sort by work-life-balance score to surface the lowest-burnout roles first.

Who is hiring nurse practitioners in Missouri right now?

Employers currently hiring for nurse practitioner roles include CVS Health, GoHealth Urgent Care, Swope Health, Cardinal Correctional Care, and others. WeekdayDoc aggregates verified openings from these and other organizations, refreshed daily.

How many nurse practitioner jobs in missouri are available, and how often are they updated?

There are currently 316 nurse practitioners positions in Missouri listed, with new roles added as employers post them. Job descriptions are public. Verified sign-in with Google or email gives free access to regular Apply, full search, and standard Market Insights. Saved jobs, My Search, and the dashboard also require verified sign-in. Eligible featured employer listings allow Apply without signup or email. Basic calculators are public and free; optional AI contract analysis, RVU Billing Optimizer, and Schedule Optimizer reports remain paid.