259+ Nurse Practitioner Jobs in Missouri
Nurse Practitioner positions in Missouri with $100K-$150K salary ranges, burnout scores, and schedule details shown upfront. Filter by no call, remote, and weekday-only.
259+ positions available
259+ Nurse Practitioner Jobs in Missouri Available Now
These 139 roles pay ~$168k median with 6.4/10 median work-life balance — use these as your benchmarks.
in Obstetrics & Gynecology (NP)
Nurse Practitioner (ACNP) - Acute & Critical Care Surgery
Washington University in St. Louis
in Critical Care Medicine (NP)
6.4/10
6.1/10
Psychiatric Mental Health Nurse Practitioner (PMHNP)
LifeStance HealthTop Employer
6.0/10
Nurse Practitioner or Physician Assistant - Richmond Heights/Clayton - Part Time!
Esse HealthGreat Workplace
Prescribing Nurse Practitioner or Physician Assistant - Holliday, MO - 1099 Contract
Lyra Health
Prescribing Nurse Practitioner or Physician Assistant - Columbia, MO - 1099 Contract
Lyra Health
Nurse Practitioner or Physician Assistant (PRN) - In-Home Health Assessments
Matrix Medical NetworkGreat Workplace
A nurse practitioner in missouri role paying $125/visit is hidden in this list.
258 more hidden below, ranked by pay and work-life.
Nurse Practitioner - Hospice
One-time payment · dashboard + negotiation brief on every application
2 more roles in this search — preview locked listings
How Missouri Compares for Nurse Practitioner Pay
Missouri against neighboring states and the top payers, from our own nurse practitioner postings over the last 12 months — not a salary survey.
Nurse Practitioner roles in Missouri advertise $5k below the $136k median across the 51 states we can measure, where New Hampshire leads at $170k.
| State | Median pay | vs MO | WLB | Listings |
|---|---|---|---|---|
| Missouri (this page) | $131k | — | 5.9/10 | 616 |
| Illinoisborders | $140k | +$9k | 5.1/10 | 1333 |
| Kansasborders | $135k | +$4k | 5.9/10 | 229 |
| Arkansasborders | $130k | −$1k | 5.8/10 | 230 |
| Oklahomaborders | $128k | −$3k | 5.4/10 | 279 |
| Nebraskaborders | $126k | −$5k | 5.4/10 | 160 |
| Kentuckyborders | $126k | −$5k | 5.8/10 | 275 |
| Iowaborders | $122k | −$9k | 5.5/10 | 339 |
“borders” = shares a border with Missouri; “#n” = national pay rank among the 51 measured states.
Missouri Jobs
259+ nurse practitioner positions in Missouri
Competitive Pay
Earn $100K-$150K with benefits
Updated Daily
New positions added daily
Nurse Practitioner Jobs in Missouri: Salary, Outlook & Work-Life Balance
Missouri offers a competitive market for healthcare professionals seeking nurse practitioner jobs in missouri. With 259+ open positions and salaries ranging from $50K to $300K, clinicians have strong options for career growth and work-life balance. 25% of listed positions offer remote or hybrid arrangements.
Every listing is evaluated using WeekdayDoc's proprietary work-life balance scoring system. Nurse Practitioner Jobs in Missouri on this page have an average score of 5.5/10, with 25% offering remote work. This data helps clinicians quickly identify positions that match their lifestyle priorities without reading through hundreds of job descriptions.
Leading employers currently hiring for nurse practitioner jobs in missouri include CVS Health, VitalCore Health Strategies, Lyra Health, Swope Health, and more. Positions span nurse practitioner jobs missouri. New jobs are added daily as healthcare organizations expand their teams.
Among the top-rated employers hiring for nurse practitioner jobs in missouri, Sailor Health (score: 97.0/100), GLOBAL OUTREACH TELEREHABILITATION (score: 96.8/100), Talkiatry (score: 96.4/100) have earned WeekdayDoc's Top Employer designation based on our proprietary ranking system. This ranking evaluates burnout scores (40%), salary competitiveness (30%), and work-life balance features like no-call and remote options (30%). See the full rankings on our Top Employers page.
According to WeekdayDoc's Market Pulse — which tracks real-time compensation data from thousands of active job postings — the current median salary is $107K, trending up 1.3% over the past quarter. This data is derived from 79,590+ job postings analyzed over the past 12 months — updated daily, unlike annual survey-based reports. Explore salary trends and burnout data on our Market Pulse dashboard.
Frequently Asked Questions
How much do nurse practitioners earn in Missouri?
Listed nurse practitioners in Missouri on WeekdayDoc pay roughly $50K to $300K per year, with a median near $114K. Actual pay varies by specialty, setting, experience, and shift type — every listing shows its salary upfront.
Are there remote or hybrid nurse practitioners jobs available?
Yes — about 25% of current nurse practitioners listings offer remote or hybrid work. You can filter for telehealth and work-from-home options, and every listing shows its remote status before you apply.
Which nurse practitioners jobs have the best work-life balance?
Every nurse practitioner role on WeekdayDoc is scored for burnout risk using call schedule, weekend and night requirements, and remote flexibility. You can sort by work-life-balance score to surface the lowest-burnout roles first.
Who is hiring nurse practitioners in Missouri right now?
Employers currently hiring for nurse practitioner roles include CVS Health, VitalCore Health Strategies, Lyra Health, Swope Health, and others. WeekdayDoc aggregates verified openings from these and other organizations, refreshed daily.
How many nurse practitioner jobs in missouri are available, and how often are they updated?
There are currently 259+ nurse practitioners positions in Missouri listed, with new roles added daily as employers post them. Create a free account to compare salaries and work-life-balance scores side by side, then apply directly.
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