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259+ Nurse Practitioner Jobs in Missouri

Nurse Practitioner positions in Missouri with $100K-$150K salary ranges, burnout scores, and schedule details shown upfront. Filter by no call, remote, and weekday-only.

259+ positions available

259+ Nurse Practitioner Jobs in Missouri Available Now

These 139 roles pay ~$168k median with 6.4/10 median work-life balance — use these as your benchmarks.

Esse Health logo

Nurse Practitioner - F/T - Watson Primary Care

Esse HealthGreat Workplace

No NightsNo Weekends
Top 25%

in Family Medicine (NP)

Esse Health logo

Nurse Practitioner or Physician Assistant - F/T - Fenton - Dr. Kolli's Office

Esse HealthGreat Workplace

No NightsNo Weekends
Top 10%

in Primary Care (NP)

Esse Health logo

Nurse Practitioner or Physician Assistant - P/T or F/T - Fenton Family Medicine

Esse HealthGreat Workplace

No NightsNo Weekends
Top 25%

in Family Medicine (NP)

Esse Health logo

Nurse Practitioner - F/T - Watson Primary Care

Esse HealthGreat Workplace

No NightsNo Weekends
Top 10%

in Primary Care (NP)

Esse Health logo

Nurse Practitioner or Physician Assistant - F/T - Fenton - Dr. Kolli's Office

Esse HealthGreat Workplace

No CallNo Nights
Top 10%

in Primary Care (NP)

Cherokee Federal logo

Nurse Practitioner, APRN, FNP

Cherokee Federal

No CallNo Nights
Top 25%

in Family Medicine (NP)

Centurion Health logo

Nurse Practitioner (NP) - Moberly, Missouri (82304)

Centurion Health

No CallNo Nights
Top 5%

in Correctional Medicine (NP)

BJC HealthCare logo

Nurse Practitioner or Physician Assistant for Primary Care at South County on Telegraph Rd. (Family Medicine)

BJC HealthCare

No CallNo Nights
Top 10%

in Primary Care (NP)

BJC HealthCare logo

Women's Health Nurse Practitioner at West End OBGYN

BJC HealthCare

No CallNo Nights
Top 5%

in Obstetrics & Gynecology (NP)

Centurion Health logo

Nurse Practitioner (NP/PA) - Farmington, MO (81442)

Centurion Health

No CallNo Nights
Top 5%

in Correctional Medicine (NP)

Centurion Health logo

Full-time Nurse Practitioner (NP/PA) - Tipton, Missouri (80799)

Centurion Health

No CallNo Nights
Top 5%

in Correctional Medicine (NP)

Centurion Health logo

Full-time, Nurse Practitioner (NP) - Jefferson City, Missouri (80023)

Centurion Health

No CallNo Nights
Top 5%

in Correctional Medicine (NP)

Centurion Health logo

Nurse Practitioner (NP/PA) - St. Joseph, Missouri (79890)

Centurion Health

No CallNo Nights
Top 25%

in Family Medicine (NP)

Centurion Health logo

Full-time Nurse Practitioner (NP) - Vandalia, Missouri (79610)

Centurion Health

No CallNo Nights
Top 25%

in Family Medicine (NP)

Centurion Health logo

Full-time, Nurse Practitioner (NP) - Boonville, Missouri (78353)

Centurion Health

No CallNo Nights
Top 25%

in Family Medicine (NP)

Centurion Health logo

Full-time, Nurse Practitioner (NP) - Bonne Terre, Missouri (76738)

Centurion Health

No CallNo Nights
Top 25%

in Family Medicine (NP)

Esse Health logo

Care Manager - Nurse Practitioner - PRN

Esse HealthGreat Workplace

No NightsNo Weekends
Top 10%

in Primary Care (NP)

A family medicine role paying $125/visit is hidden in this list.

258 more hidden below, ranked by pay and work-life.

Your Family Medicine DashboardUpdated daily
#1 Match
7.1/10

Nurse Practitioner - Hospice

Savannah, Missouri125/visit
+ 258 more · up to $125/visit
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1 more role in this search — preview locked listings

How Missouri Compares for Nurse Practitioner Pay

Missouri against neighboring states and the top payers, from our own nurse practitioner postings over the last 12 months — not a salary survey.

Median advertised
$131k
Pay rank
#39 of 51
Work-life balance
5.9/10 · #18
Open listings
616

Nurse Practitioner roles in Missouri advertise $5k below the $136k median across the 51 states we can measure, where New Hampshire leads at $170k.

Nurse Practitioner median pay and work-life-balance score, Missouri compared with neighboring states and the highest-paying states
StateMedian payvs MOWLBListings
Missouri (this page)$131k5.9/10616
Illinoisborders$140k+$9k5.1/101333
Kansasborders$135k+$4k5.9/10229
Arkansasborders$130k−$1k5.8/10230
Oklahomaborders$128k−$3k5.4/10279
Nebraskaborders$126k−$5k5.4/10160
Kentuckyborders$126k−$5k5.8/10275
Iowaborders$122k−$9k5.5/10339

“borders” = shares a border with Missouri; “#n” = national pay rank among the 51 measured states.

Missouri Jobs

259+ nurse practitioner positions in Missouri

Competitive Pay

Earn $100K-$150K with benefits

Updated Daily

New positions added daily

Nurse Practitioner Jobs in Missouri: Salary, Outlook & Work-Life Balance

Missouri offers a competitive market for healthcare professionals seeking nurse practitioner jobs in missouri. With 259+ open positions and salaries ranging from $95K to $164K, clinicians have strong options for career growth and work-life balance.

Every listing is evaluated using WeekdayDoc's proprietary work-life balance scoring system. Nurse Practitioner Jobs in Missouri on this page have an average score of 8/10, with 74% with no on-call requirements, 100% with no weekends. This data helps clinicians quickly identify positions that match their lifestyle priorities without reading through hundreds of job descriptions.

Leading employers currently hiring for nurse practitioner jobs in missouri include Centurion Health, Esse Health, BJC HealthCare, Cherokee Federal, and more. Positions span nurse practitioner jobs missouri. New jobs are added daily as healthcare organizations expand their teams.

Among the top-rated employers hiring for nurse practitioner jobs in missouri, Sailor Health (score: 97.0/100), GLOBAL OUTREACH TELEREHABILITATION (score: 96.8/100), Talkiatry (score: 96.4/100) have earned WeekdayDoc's Top Employer designation based on our proprietary ranking system. This ranking evaluates burnout scores (40%), salary competitiveness (30%), and work-life balance features like no-call and remote options (30%). See the full rankings on our Top Employers page.

According to WeekdayDoc's Market Pulse — which tracks real-time compensation data from thousands of active job postings — the current median salary is $107K, trending up 1.3% over the past quarter. This data is derived from 79,590+ job postings analyzed over the past 12 months — updated daily, unlike annual survey-based reports. Explore salary trends and burnout data on our Market Pulse dashboard.

Frequently Asked Questions

How much do nurse practitioners earn in Missouri?

Listed nurse practitioners in Missouri on WeekdayDoc pay roughly $95K to $164K per year, with a median near $95K. Actual pay varies by specialty, setting, experience, and shift type — every listing shows its salary upfront.

Are there remote or hybrid nurse practitioners jobs available?

Some nurse practitioners roles offer remote or hybrid flexibility. You can filter for telehealth and work-from-home options, and every listing shows its remote status before you apply.

Which nurse practitioners jobs have the best work-life balance?

Every nurse practitioner role on WeekdayDoc is scored for burnout risk using call schedule, weekend and night requirements, and remote flexibility. Among current listings, 74% with no on-call and 100% with no weekends. You can sort by work-life-balance score to surface the lowest-burnout roles first.

Who is hiring nurse practitioners in Missouri right now?

Employers currently hiring for nurse practitioner roles include Centurion Health, Esse Health, BJC HealthCare, Cherokee Federal, and others. WeekdayDoc aggregates verified openings from these and other organizations, refreshed daily.

How many nurse practitioner jobs in missouri are available, and how often are they updated?

There are currently 259+ nurse practitioners positions in Missouri listed, with new roles added daily as employers post them. Create a free account to compare salaries and work-life-balance scores side by side, then apply directly.

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