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259+ Nurse Practitioner Jobs in Missouri

Nurse Practitioner positions in Missouri with $100K-$150K salary ranges, burnout scores, and schedule details shown upfront. Filter by no call, remote, and weekday-only.

259+ positions available

259+ Nurse Practitioner Jobs in Missouri Available Now

These 139 roles pay ~$168k median with 6.4/10 median work-life balance — use these as your benchmarks.

CoxHealth logo

NP or PA Inpatient Rehab - Hospital Medicine

CoxHealth

No Nights
Above avg

in Hospital Medicine (NP)

Us Oncology logo

Nurse Practitioner

Us Oncology

No Weekends
Alteas Health logo

Nurse Practitioner

Alteas Health

No Weekends
American Oncology Network logo

APRN

American Oncology Network

Nurse PractitionerSpringfield, MO
80k - $170k
30+ days ago
No Weekends
Washington University in St. Louis logo

Nurse Practitioner or Physician Assistant (Hybrid) - Neurology

Washington University in St. Louis

HybridNo Nights
Top 5%

in Neurology (NP)

Commonwealth Medical Services logo

Nurse Practitioner - Kansas City, MO - Part Time - 1-3 days per week

Commonwealth Medical ServicesGreat Workplace

No NightsNo Weekends
Top 5%

in Occupational Medicine (NP)

Commonwealth Medical Services logo

Nurse Practitioner - (Part-Time) - Kirksville, MO

Commonwealth Medical ServicesGreat Workplace

Nurse PractitionerKirksville, MO
600–$750 per day
3w ago
No NightsNo Weekends
Top 5%

in Nurse Practitioner roles

Commonwealth Medical Services logo

Nurse Practitioner - (Part-Time) - Cape Girardeau, MO

Commonwealth Medical ServicesGreat Workplace

Nurse PractitionerCape Girardeau, MO
600–$750 per day
30+ days ago
No NightsNo Weekends
Top 5%

in Nurse Practitioner roles

Commonwealth Medical Services logo

Nurse Practitioner - (Part-Time) - Kennett, MO

Commonwealth Medical ServicesGreat Workplace

Nurse PractitionerKennett, MO
600–$750 per day
30+ days ago
No NightsNo Weekends
Top 5%

in Family Medicine (NP)

Commonwealth Medical Services logo

Nurse Practitioner - (Part-Time) - Poplar Bluff, MO

Commonwealth Medical ServicesGreat Workplace

Nurse PractitionerPoplar Bluff, MO
600–$750 per day
30+ days ago
No NightsNo Weekends
Top 5%

in Family Medicine (NP)

Commonwealth Medical Services logo

Nurse Practitioner - (Part-Time) - West Plains, MO

Commonwealth Medical ServicesGreat Workplace

Nurse PractitionerWest Plains, MO
600–$750 per day
30+ days ago
No NightsNo Weekends
Top 5%

in Family Medicine (NP)

Commonwealth Medical Services logo

Nurse Practitioner - (Part-Time) - Lee's Summit, MO

Commonwealth Medical ServicesGreat Workplace

Nurse PractitionerLee's Summit, MO
600–$750 per day
30+ days ago
No NightsNo Weekends
Top 5%

in Occupational Medicine (NP)

Commonwealth Medical Services logo

Nurse Practitioner - Jefferson City, MO - Part Time - 3 days per week

Commonwealth Medical ServicesGreat Workplace

No NightsNo Weekends
Top 5%

in Nurse Practitioner roles

Pinnacle Wound Management logo

Wound Care Nurse Practitioner

Pinnacle Wound ManagementTop Employer

No CallNo Nights
Top 5%

in Wound Care (NP)

Pinnacle Wound Management logo

Wound Care Nurse Practitioner

Pinnacle Wound ManagementTop Employer

No CallNo Nights
Top 5%

in Wound Care (NP)

Pinnacle Wound Management logo

Wound Care Nurse Practitioner

Pinnacle Wound ManagementTop Employer

No CallNo Nights
Top 5%

in Wound Care (NP)

Advantmed logo

Field Nurse Practitioner - St. Louis County, MO

AdvantmedGreat Workplace

No CallNo Nights
Top 5%

in Family Medicine (NP)

A nurse practitioner in missouri role paying $125/visit is hidden in this list.

258 more hidden below, ranked by pay and work-life.

Your Nurse Practitioner in Missouri DashboardUpdated daily
#1 Match
7.1/10

Nurse Practitioner - Hospice

Savannah, Missouri125/visit
+ 258 more · up to $125/visit
90-day pass — $57One-time · 90 days · no subscription, no auto-renew

One-time payment · dashboard + negotiation brief on every application

2 more roles in this search — preview locked listings

How Missouri Compares for Nurse Practitioner Pay

Missouri against neighboring states and the top payers, from our own nurse practitioner postings over the last 12 months — not a salary survey.

Median advertised
$131k
Pay rank
#39 of 51
Work-life balance
5.9/10 · #18
Open listings
616

Nurse Practitioner roles in Missouri advertise $5k below the $136k median across the 51 states we can measure, where New Hampshire leads at $170k.

Nurse Practitioner median pay and work-life-balance score, Missouri compared with neighboring states and the highest-paying states
StateMedian payvs MOWLBListings
Missouri (this page)$131k5.9/10616
Illinoisborders$140k+$9k5.1/101333
Kansasborders$135k+$4k5.9/10229
Arkansasborders$130k−$1k5.8/10230
Oklahomaborders$128k−$3k5.4/10279
Nebraskaborders$126k−$5k5.4/10160
Kentuckyborders$126k−$5k5.8/10275
Iowaborders$122k−$9k5.5/10339

“borders” = shares a border with Missouri; “#n” = national pay rank among the 51 measured states.

Missouri Jobs

259+ nurse practitioner positions in Missouri

Competitive Pay

Earn $100K-$150K with benefits

Updated Daily

New positions added daily

Nurse Practitioner Jobs in Missouri: Salary, Outlook & Work-Life Balance

Missouri offers a competitive market for healthcare professionals seeking nurse practitioner jobs in missouri. With 259+ open positions and salaries ranging from $45K to $195K, clinicians have strong options for career growth and work-life balance.

Every listing is evaluated using WeekdayDoc's proprietary work-life balance scoring system. Nurse Practitioner Jobs in Missouri on this page have an average score of 7.9/10, with 25% with no on-call requirements, 95% with no weekends, 10% offering remote work. This data helps clinicians quickly identify positions that match their lifestyle priorities without reading through hundreds of job descriptions.

Leading employers currently hiring for nurse practitioner jobs in missouri include Commonwealth Medical Services, Pinnacle Wound Management, Advantmed, Esse Health, and more. Positions span nurse practitioner jobs missouri. New jobs are added daily as healthcare organizations expand their teams.

Among the top-rated employers hiring for nurse practitioner jobs in missouri, Sailor Health (score: 97.0/100), GLOBAL OUTREACH TELEREHABILITATION (score: 96.8/100), Talkiatry (score: 96.4/100) have earned WeekdayDoc's Top Employer designation based on our proprietary ranking system. This ranking evaluates burnout scores (40%), salary competitiveness (30%), and work-life balance features like no-call and remote options (30%). See the full rankings on our Top Employers page.

According to WeekdayDoc's Market Pulse — which tracks real-time compensation data from thousands of active job postings — the current median salary is $107K, trending up 1.3% over the past quarter. This data is derived from 79,590+ job postings analyzed over the past 12 months — updated daily, unlike annual survey-based reports. Explore salary trends and burnout data on our Market Pulse dashboard.

Frequently Asked Questions

How much do nurse practitioners earn in Missouri?

Listed nurse practitioners in Missouri on WeekdayDoc pay roughly $45K to $195K per year, with a median near $117K. Actual pay varies by specialty, setting, experience, and shift type — every listing shows its salary upfront.

Are there remote or hybrid nurse practitioners jobs available?

Yes — about 10% of current nurse practitioners listings offer remote or hybrid work. You can filter for telehealth and work-from-home options, and every listing shows its remote status before you apply.

Which nurse practitioners jobs have the best work-life balance?

Every nurse practitioner role on WeekdayDoc is scored for burnout risk using call schedule, weekend and night requirements, and remote flexibility. Among current listings, 25% with no on-call and 95% with no weekends. You can sort by work-life-balance score to surface the lowest-burnout roles first.

Who is hiring nurse practitioners in Missouri right now?

Employers currently hiring for nurse practitioner roles include Commonwealth Medical Services, Pinnacle Wound Management, Advantmed, Esse Health, and others. WeekdayDoc aggregates verified openings from these and other organizations, refreshed daily.

How many nurse practitioner jobs in missouri are available, and how often are they updated?

There are currently 259+ nurse practitioners positions in Missouri listed, with new roles added daily as employers post them. Create a free account to compare salaries and work-life-balance scores side by side, then apply directly.

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