Esse Health logo
Esse Health
St. Peters, Missouri

Nurse Practitioner or Physician Assistant - F/T - St. Peters & Florissant

Physician AssistantIncludes callIncludes weekendsNo nightsFull-Time

Listed compensation

$99k-$125k

The week · per this posting · Monday – Friday

Weekend work is also flagged as required; confirm which days and how often.

Ask the employer about the work setting and time off.

Posted 38m ago · Verified live

Job Description

Esse Health is the largest independent physician practice in the St. Louis

Metropolitan area with over 100+ physicians, in 35+ locations, serving nearly

130,000 patients. We are leading the healthcare community by placing patients and their physicians at the center of health decisions. Esse Health is more than a healthcare provider - it's a place where medicine is a calling and not just a profession. It's a team of extraordinary medical professionals with the latest ideas for keeping patients healthier.

Practice with independence and at the highest level of your training!

Join Our Team

Esse Health is currently seeking a compassionate full-time Advanced Practice

Provider (NP/PA) for our office of Dr.'s Knapp & Miranda!

Opportunity

  • Full-time opening
  • Monday - Friday, 8 hours a day (Fridays may be a bit shorter)
  • 2 days at St. Peters office location (4800 Mexico Road) & 3 days at

Florissant office location (2187 Charbonier Road)

  • No nights, weekends, or holidays
  • Outpatient focused clinical practice
  • Call approximately one weekend a month (low volume)

Day-to-Day

  • Join a collaborative team and develop a 1:1 relationship with patients and clinical staff members
  • Provide comprehensive primary care services to adult patients
  • Conduct patient evaluations, physical exams, and diagnostic assessments
  • Diagnose and manage acute and chronic conditions
  • Develop and implement treatment plans in collaboration with physician partner
  • Emphasize preventive care, wellness, and patient education
  • Document patient care accurately and efficiently in the electronic health record (NextGen)
  • Coordinate care with specialists and other members of the healthcare team
  • Participate in quality improvement and care coordination initiatives

Qualifications

  • Master’s Degree of Science in Nursing or Physician Assistant-Master’s Degree
  • Current Nurse Practitioner or Physician Assistant licensure in Missouri (or eligibility)
  • Certified Physician Assistant or Certified Nurse Practitioner (or eligibility)
  • Strong clinical, communication, and interpersonal skills
  • Commitment to patient-centered, team-based care
  • Ability to work independently while collaborating closely with physicians

What We Offer

  • Physician-led, supportive practice environment
  • Competitive compensation: The starting salary for entry level will likely be in the $99,000 - $112,000 range (factors may include candidate experience and specific role within the office). Up to $125,000/year may be considered for candidate's with an average of 8 -10 years of NP/PA experience.
  • Benefits within your first 30 days
  • Available benefits: Medical, Dental, Vision, Life, Long/Short Term
  • Disability, Health Savings Account/Flexible Spending Account, Fraud
  • Protection, Legal, Pet and other miscellaneous
  • Generous PTO policy + 9 paid holidays
  • 401k match + profit sharing
  • Tuition reimbursement
  • Wellness program
  • Opportunities for professional growth and mentorship
  • Emphasis on work-life balance
  • Modern facilities and integrated care teams

EOE

Key Responsibilities

Provide comprehensive primary care services to adult patients, including conducting evaluations, diagnosing conditions, and implementing treatment plans. Collaborate with physician partners and clinical staff to coordinate care and participate in quality improvement initiatives.

Qualifications

Education
Professional certificate or licensure
Experience
10+ years of experience

Key Skills

Patient evaluationTreatment planningElectronic health recordsClinical documentationCommunication skills

Work-Life Balance Analysis

WeekdayDoc's proprietary algorithm rates Nurse Practitioner or Physician Assistant - F/T - St. Peters & Florissant at Esse Health a 6.4 out of 10 for work-life balance — classified as good. This places the position in the Above average in Family Medicine (PA) — ranked against 814 active Family Medicine (PA) listings on WeekdayDoc. Contributing factors include no night shifts.

Family Medicine — Physician Assistant Career Context

Esse Health ranks #12 of 14 employers hiring Physician Assistant on WeekdayDoc by average advertised pay, and holds silver-tier status on the Top Employers work-life index, composite score 79/100, 34 active listings.

Of the 50 active Family Medicine listings this role was benchmarked against, 4% are remote, 74% have no call, 74% require no weekends.

Family Medicine by the numbers
MeasureThis jobMarket
Work-life score6.4 / 10 · above average in family medicine (pa)ranked against 814 Family Medicine (PA) listingslisting-based score, 0–10
Listed pay$99k–$125kFamily Medicine median $126k (middle half $110k–$155k)42 comparable listings, Nov 2026
Cost-of-living adjusted pay~$123k in purchasing powerMissouri index 90.8 (US = 100)BEA Regional Price Parities (2024)
Family Medicine listings in Missouri13 active879 nationallylive on WeekdayDoc, Nov 2026
Work settingon-sitepeers: 4% remote · 74% no call · 74% no weekends50 benchmarked listings
Sign-on & loan repaymentnot statedUS Physician Assistant listings: 23% state a sign-on bonus (median $15k) · 8% offer loan repayment1,000 active listings, Nov 2026
Family Medicine hiring demand#2 of 6 specialtiespostings stay open a median 52 days · 30% state a sign-on bonusWeekdayDoc Hiring Index, October 2026 · 409 postings, 124 closed
New Family Medicine listings2,046 in the last 30 days1,408 the 30 days before (+45%)U.S., first seen on WeekdayDoc, Nov 2026
Family Medicine pay trend+3.2% vs prior quarter—through Oct 2026
Esse Healthsilver tier, 79/100 · #12 of 14 for payTop Employers work-life index34 active listings
Sources: WeekdayDoc live listing index (814 Family Medicine (PA) listings), Top Employers work-life index, BEA Regional Price Parities (2024), WeekdayDoc Hiring Index; as of Nov 2026. Same values as the Weekday Verdict and Market Insights on this page.

Top Physician Assistant Jobs

36 matches · ranked by pay

Salary Distribution

36 jobs · 30 employers
10
<$140k
11
$140k-160k
5
$160k-180k
8
$180k-200k
2
$200k+

Annual compensation range

Benefits & Perks

34 jobs · 30 employers
401k / retirement match
91% this job
CME allowance
62%
Sign-on bonus
44%
Loan repayment
18%
Relocation assistance
9%

Share of similar jobs offering each benefit

#1

Clinic Director - Physician Assistant (PA-C) or Nurse Practitioner (NP)

Ageless Mens Health · Memphis, Tennessee

$210k
#2

Nurse Practitioner (NP) or Physician Assistant (PA) - Bangor/Brewer, ME

Constellation Health Services · Bangor, Maine

$110k-$200k
#3

Family Nurse Practitioner (FNP) / Physician Assistant (PA) – Mobile Primary Care

$185k-$195k
#4

Clinic Director - Physician Assistant (PA-C) or Nurse Practitioner (NP)

$195k
+ 34 more · ranked by pay

Work-life snapshot

median 4.8this job 6.4
Better work-life than 70% of Family Medicine (PA) listings

Listing-based score, 0–10, across 814 comparable listings. Shaded area = the share scoring below this one.

  • No nights
  • On-site
  • Includes call
  • Includes weekends
Esse Health logo

About Esse Health

Medical Practices
St. Louis, Missouri
501-1,000 employees

Benefits & Perks

Medical, Dental, Vision
Life Insurance
Long/Short Term Disability
Health Savings Account/Flexible Spending Account
401k match + profit sharing
Generous PTO + 9 paid holidays
Tuition reimbursement
Wellness program

Living in St. Peters

Typical 3-bedroom home value
$319k≈ 3.2× annual pay
Typical market rent
$1,687/mo≈ 20% of gross pay
Residents’ average commute
23 min
Metro price indexU.S. average = 100
95.1
State income tax
Up to 5.3%
Sources & methodology

Sources: Zillow home values (Sep 2026), Zillow market rents (Sep 2026), U.S. Census ACS 2024 five-year.

BEA 2024 · St. Louis, MO-IL metro prices. Housing figures are city-level.

Ratios use this listing’s gross annual pay. Not a cost-of-living guarantee.