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Mayo Clinic
Jacksonville, Florida

Nurse Practitioner or Physician Assistant II - Hospital Internal Medicine (Nights)

Physician AssistantFull-Time

Compensation

Pay not listed

The week · per this posting · weekdays assumed

Ask the employer about the pay range, the work setting, call expectations and time off.

Posted 1h ago · Verified live

Job Description

The APP performs the following tasks in any authorized setting (hospitals).

  • Obtaining patient history
  • Performing physical examinations
  • Ordering and performing diagnostic and therapeutic procedures
  • Formulating a diagnostic impression
  • Developing and implementing a treatment plan
  • Monitoring effectiveness of therapeutic interventions
  • Offering counseling and education to meet patient needs
  • Making appropriate referrals
  • Prescribing and dispensing prescription medication
  • Performing minor procedures
  • Demonstrates ability to assess data reflective of patient's status and appropriately interprets information relative to patient's age-specific needs.

During the selection process you may participate in an OnDemand (pre-recorded) interview that you can complete at your convenience. During the OnDemand interview, a question will appear on your screen, and you will have time to consider each question before responding.

You will have the opportunity to re-record your answer to each question – Mayo Clinic will only see the final recording. The complete interview will be reviewed by a Mayo Clinic staff member and you will be notified of next steps.

Qualifications

Due to the complexity of our patient population, new graduates will not be considered at this time. 2+ years of APP experience is required

Nurse Practitioner: Masters-prepared graduate of an accredited school of nursing and Nurse Practitioner program. Current FL RN and APRN license and certification as a FNP, ANP or ACNP.

Physician Assistant: Graduate of accredited Physician Assistant program with current PA certification by NCCPA and registration as a PA by the FL State Board of Medical Practice.

Additional Qualifications

Active BLS and ACLS certification from American Heart Association or American Red Cross at start date and DEA registration required

Why Mayo Clinic

Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans – to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.

Benefits Highlights

  • Medical: Multiple plan options.
  • Dental: Delta Dental or reimbursement account for flexible coverage.
  • Vision: Affordable plan with national network.
  • Pre-Tax Savings: HSA and FSAs for eligible expenses.
  • Retirement: Competitive retirement package to secure your future.

Just as our reputation has spread beyond our Minnesota roots, so have our locations.

Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations.

Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is.

Equal Opportunity

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law". Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.

Key Responsibilities

The Advanced Practice Provider will perform physical examinations, order diagnostic tests, and formulate treatment plans for hospital internal medicine patients. They are also responsible for monitoring therapeutic effectiveness, providing patient education, and performing minor procedures.

Qualifications

Education
Master's degree (postgraduate degree)
Experience
2+ years of experience

Certifications

DEA License

Key Skills

Patient history takingDiagnostic proceduresTreatment planningPatient counselingPrescribing medicationData assessmentBLS certification

Internal Medicine — Physician Assistant Career Context

Of the 50 active Physician Assistant listings this role was benchmarked against, 6% are remote, 68% have no call, 76% require no weekends.

Physician Assistant pay on WeekdayDoc is up 2.0% vs. the prior quarter (through Oct 2026).

Physician Assistant by the numbers
MeasureThis jobMarket
Listed paynot listedPhysician Assistant median $126k (middle half $110k–$155k)42 comparable listings, Nov 2026
Cost of livingFlorida index 103.4US average = 100BEA Regional Price Parities (2024)
Physician Assistant listings in Florida226 active4,700 nationallylive on WeekdayDoc, Nov 2026
Work settingon-sitepeers: 6% remote · 68% no call · 76% no weekends50 benchmarked listings
Sign-on & loan repaymentnot statedFlorida Physician Assistant listings: 14% state a sign-on bonus · 6% offer loan repayment226 active listings, Nov 2026
Internal Medicine hiring demandnot ranked this monthpostings stay open a median 50 daysWeekdayDoc Hiring Index, October 2026 · 31 postings, 37 closed
New Internal Medicine listings571 in the last 30 days341 the 30 days before (+67%)U.S., first seen on WeekdayDoc, Nov 2026
Physician Assistant pay trend+2.0% vs prior quarter—through Oct 2026
Sources: WeekdayDoc live listing index, BEA Regional Price Parities (2024), WeekdayDoc Hiring Index; as of Nov 2026. Same values as the Weekday Verdict and Market Insights on this page.

Location & Logistics

Florida has no state income tax, which can significantly increase take-home pay compared to high-tax states.

Top Physician Assistant Jobs

48 matches · ranked by pay

Salary Distribution

48 jobs · 35 employers
13
<$145k
9
$145k-170k
17
$170k-195k
5
$195k-220k
4
$220k+

Annual compensation range

Benefits & Perks

43 jobs · 35 employers
401k / retirement match
81% this job
CME allowance
51%
Sign-on bonus
42%
Loan repayment
23%
Relocation assistance
16%

Share of similar jobs offering each benefit

#1

Physician AssistantContract

Akicita Federal · Rosebud, South Dakota

$229k-$239k
#2

Outpatient Advanced Practice Provider (APP), Nurse Practitioner or Physician Assistant/Associates

Oregon Health & Science University · Portland, Oregon

$172k-$229k
#3

Advanced Practice Provider (APP), Nurse Practitioner or Physician Assistant/Associate

$172k-$229k
#4

Family Nurse Practitioner - NP/PA

$50.22-$108.15/hr
+ 46 more · ranked by pay

Work-life snapshot

median 4.8this job 3.0
Below most Internal Medicine (PA) listings for work-life

Listing-based score, 0–10, across 77 comparable listings. Shaded area = the share scoring below this one.

Mayo Clinic logo

About Mayo Clinic

Hospitals and Health Care
Rochester, Minnesota
10,000+ employees

Benefits & Perks

Medical: Multiple plan options
Dental: Delta Dental or reimbursement account
Vision: Affordable plan with national network
Pre-Tax Savings: HSA and FSAs
Retirement: Competitive retirement package

Living in Jacksonville

Typical 3-bedroom home value
$270k
Typical market rent
$1,589/mo
Residents’ average commute
24 min
Metro price indexU.S. average = 100
99.5
State income tax
None
Sources & methodology

Sources: Zillow home values (Sep 2026), Zillow market rents (Sep 2026), U.S. Census ACS 2024 five-year.

BEA 2024 · Jacksonville, FL metro prices. Housing figures are city-level.

City-level figures. Not a cost-of-living guarantee.