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Moffitt Cancer Center
Tampa, Florida

Clinical Research Nurse I - Breast

Registered NurseFull-Time

Listed compensation

$37.03-$56.53/hr

The week · per this posting · weekdays assumed

Ask the employer about call expectations, weekend coverage, nights and shift pattern and time off.

Posted 25m ago · Verified live

Job Description

Working at Moffitt is both a career and a mission: to contribute to the prevention and cure of cancer.

As the only National Cancer Institute-designated Comprehensive Cancer Center based in Florida, Moffitt employs some of the best and brightest minds from around the world. Join a dedicated team of nearly 11,000 who are shaping the future we envision. Moffitt has been recognized as a Best and Brightest Company to Work For in the Nation and is continually named one of the Tampa Bay Times’ Top Workplaces.

Summary

The Clinical Research RN I (CRN I) facilitates clinical research activity at Moffitt Cancer Center and/or affiliated institutions by leading the coordination of opening new protocols, new patient evaluation, registering eligible patients and coordinating protocol‐related care of patients enrolled on clinical trials.

The CRN I is required to have an in‐depth knowledge of protocol requirements and good clinical practices as set forth by Federal regulations.

As the primary resource for the protocols, the research nurse will coordinate and provide direct patient care, perform ongoing assessments, deliver patient education, and document in accordance with standards and regulatory guidelines pertaining to specified research patients enrolled onto Moffitt run clinical trials.

The CRN I will act as liaison between the investigators, primary care providers, Moffitt regulatory staff and the sponsor. Along with the investigator, the CRN I will screen, enroll, and follow study subjects, ensuring protocol compliance and close monitoring while the subjects are on study.

In addition, this position is responsible for data and source documentation, adverse experience reporting, maintenance of regulatory files in conjunction with the regulatory specialist, maintenance of subject accruals and protocol tracking.

Position Highlights

The Clinical Research RN I (CRN I) facilitates clinical research activity at Moffitt Cancer Center and/or affiliated institutions by leading the coordination of opening new protocols, new patient evaluation, registering eligible patients and coordinating protocol‐related care of patients enrolled on clinical trials. The CRN I is required to have an in‐depth knowledge of protocol requirements and good clinical practices as set forth by Federal regulations.

As the primary resource for the protocols, the research nurse will coordinate and provide direct patient care, perform ongoing assessments, deliver patient education, and document in accordance with standards and regulatory guidelines pertaining to specified research patients enrolled onto Moffitt run clinical trials.

The CRN I will act as liaison between the investigators, primary care providers, Moffitt regulatory staff and the sponsor. Along with the investigator, the CRN I will screen, enroll, and follow study subjects, ensuring protocol compliance and close monitoring while the subjects are on study.

In addition, this position is responsible for data and source documentation, adverse experience reporting, maintenance of regulatory files in conjunction with the regulatory specialist, maintenance of subject accruals and protocol tracking.

Credentials and Qualifications

  • Bachelor’s Degree o In lieu of bachelor’s degree – associate’s degree (ASN) in Nursing
  • Two (2) years of relevant Nursing Experience
  • Current Florida RN License
  • Ability to plan, organize, and coordinate multiple work assignments.
  • Ability to establish and maintain effective, collaborative working relationships with others.
  • Ability to clearly communicate verbally and in writing.
  • Ability to establish and maintain effective, collaborative working relationships with others

Preferred

  • Basic Life Support (BLS)
  • With BSN, ADN/ASN direct research nursing experience preferred
  • Oncology Experience

An applicant for this position, who will be or is seeking Florida licensure by endorsement, must not have any National Practitioner Data Bank (NPDB) reports, unless the applicant has successfully appealed to have their name removed from the NPDB. An applicant is encouraged to conduct a NPDB Self-Query before proceeding with an employment application: npdb.hrsa.gov

Salary Range

$37.03 - $56.53

Salary ranges posted for this position represent the expected base pay range for the role. Actual compensation may vary based on location and a variety of job-related factors, including experience, skills, education, and internal equity among Team Members in similar positions.

We are committed to maintaining fair and equitable pay practices and regularly review compensation to ensure alignment across our workforce.

Moffitt Career Site

If you have the vision, passion, and dedication to contribute to our mission, then we have a place for you!

1. Equal Employment Opportunity

Moffitt Cancer Center is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, or protected veteran or disabled status. We seek candidates whose skills, and personal and professional experience, have prepared them to contribute to our commitment to diversity and excellence.

2. Reasonable Accommodation

Federal law requires employers to provide reasonable accommodation to qualified individuals with disabilities. Please tell us if you require a reasonable accommodation to apply for a job or to perform your job.

Examples of reasonable accommodation include making a change to the application process or work procedures, providing documents in an alternate format, using a sign language interpreter, or using specialized equipment. Moffitt endeavors to make moffitt.org/careers accessible to any and all users.

If you would like to contact us regarding the accessibility of our website or need assistance completing the application process, please contact one of the Human Resources receptionists by phone at 813-745-7899 or by email at HRReceptionists@moffitt.org.

This contact information is for accommodation requests only and cannot be used to inquire about the status of applications.

Read more information about your EEO rights under the law.

Transparency in Coverage Rule

Key Responsibilities

Coordinate clinical trial protocols, evaluate and enroll eligible patients, and provide protocol-related care, assessments, education, and monitoring. Maintain study data and source documentation, report adverse experiences, track accruals and protocols, and liaise with investigators, care providers, regulatory staff, and sponsors.

Requirements

Requires a bachelor’s degree, or an associate degree in nursing in lieu of a bachelor’s degree, at least two years of relevant nursing experience, and a current Florida RN license. Candidates must be able to organize multiple assignments, communicate clearly, and work collaboratively; BLS, direct research nursing experience, and oncology experience are preferred.

Qualifications

Experience
2+ years of experience

Key Skills

Clinical Research CoordinationPatient AssessmentClinical Trial Screening and EnrollmentClinical DocumentationRegulatory File MaintenanceCommunicationOrganization and Planning

Ambulatory Care Nursing — Registered Nurse Career Context

Of the 50 active Ambulatory Care Nursing listings this role was benchmarked against, 30% are remote, 42% have no call, 76% require no weekends.

In Florida, the Ambulatory Care Nursing weighted monthly median benchmark on WeekdayDoc is ~$90k (13 salary observations; 63 listings), vs ~$96k nationally (350 salary observations; 1,273 listings). Monthly aggregates cover 2026-01-01 through 2026-10-01; these are not the modal's selected comparable-job medians.

How many Ambulatory Care Nursing jobs are remote?
MeasureThis jobMarket
Florida vs national$90k median in Florida$96k nationally (−6%)13 state / 350 national salary observations
Cost-of-living adjusted pay~$94k in purchasing powerFlorida index 103.4 (US = 100)BEA Regional Price Parities (2024)
Ambulatory Care Nursing listings in Florida22 active385 nationallylive on WeekdayDoc, Oct 2026
Work settingon-sitepeers: 30% remote · 42% no call · 76% no weekends50 benchmarked listings
Sign-on & loan repaymentnot statedFlorida Registered Nurse listings: 9% state a sign-on bonus (median $10k) · 3% offer loan repayment329 active listings, Oct 2026
Ambulatory Care Nursing pay trend+1.1% vs prior quarter—through Sep 2026
Sources: WeekdayDoc live listing index, BEA Regional Price Parities (2024); as of Oct 2026. Same values as the Weekday Verdict and Market Insights on this page.

Location & Logistics

Florida has no state income tax, which can significantly increase take-home pay compared to high-tax states. At the posted ~$97k midpoint, that is roughly $4k–$7k a year versus a typical 4–7% state rate.

Top Registered Nurse Jobs

25 matches · ranked by pay

Salary Distribution

25 jobs · 22 employers
11
<$100k
4
$100k-120k
3
$120k-140k
6
$140k-160k
1
$165k

Annual compensation range

Benefits & Perks

17 jobs
401k / retirement match
94%
Sign-on bonus
18%
CME allowance
6%
PSLF eligible
6%

Share of similar jobs offering each benefit

#1

Director of Nursing DON - Acute Inpatient Mental Health 264

Telecare · Shelton, Washington

$144k-$165k
#2

Triage Staff Nurse – Days – David H Koch Center GI, Hepatology, Irritable Bowel Disease Clinic - Weill Cornell Medical Center

NewYork-Presbyterian Hospital · New York, New York

$134k-$153k
#3

Asst. Director of Nursing - Ambulatory Care - Newkirk Avenue

$136,708 - $150,000
#4

Psychiatric Nurse Manager - Women's Mental Health

$150,000 a year
+ 23 more · ranked by pay

Work-life snapshot

median 5.1this job 3.0
Better work-life than 20% of Ambulatory Care Nursing (RN) listings

Listing-based score, 0–10, across 381 comparable listings. Shaded area = the share scoring below this one.

  • On-site

Living in Tampa

Typical 3-bedroom home value
$382k
Typical market rent
$1,930/mo
Residents’ average commute
25 min
Metro price indexU.S. average = 100
100.9
State income tax
None
Sources & methodology

Sources: Zillow home values (Sep 2026), Zillow market rents (Sep 2026), U.S. Census ACS 2024 five-year.

BEA 2024 · Tampa-St. Petersburg-Clearwater, FL metro prices. Housing figures are city-level.

City-level figures. Not a cost-of-living guarantee.