Us Oncology logo
Us Oncology
Denton, Texas

Clinical Research Nurse (RN)

Registered NurseNo callNo weekendsFull-Time

Compensation

Pay not listed

The week · per this posting · Monday – Friday

Ask the employer about the pay range, the work setting, nights and shift pattern and time off.

Posted 1h ago · Verified live

Job Description

Texas Oncology is looking for a Full-time Clinical Research Nurse (RN) to join our team! This position will support the Denton, TX location. This is a Full-time Monday-Friday 8:30am-5pm position with no weekends, call, or major holidays.

This position can be level 1, 2, or Sr based on candidate experience.

Texas Oncology is the largest community oncology provider in the country and has approximately 600+ providers in 220+ sites across Texas and southeastern Oklahoma.

Our founders pioneered community-based cancer care because they believed in making the best available cancer care accessible to all communities, allowing people to fight cancer at home with the critical support of family and friends nearby.

Our mission is still the same today—at Texas Oncology, we use leading-edge technology and research to deliver high-quality, high-touch, evidence-based cancer care to help our patients achieve “More breakthroughs. More victories.” ® in their fight against cancer. Today, Texas Oncology treats half of all Texans diagnosed with cancer on an annual basis.

Why Work for Us?

Come join our team that is responsible for helping lead Texas Oncology in treating more patient diagnosed with cancer than any other provider in Texas.

We offer our employees a competitive benefits package that includes Medical, Dental, Vision, Life Insurance, Short-term and Long-term disability coverage, a generous PTO program, a 401k plan that comes with a company match, a Wellness program that rewards you practicing a healthy lifestyle, and lots of other great perks such as Tuition Reimbursement, an Employee Assistance program and discounts on some of your favorite retailers.

Joining our Northeast Texas Research team means becoming part of a supportive and highly collaborative environment where every team member's contributions are valued. We pride ourselves on responsive leadership, teamwork, and a culture that encourages learning and growth.

Join a Team That Invests in Your Future

At Texas Oncology, we recognize the long-term impact of our people and are committed to rewarding performance and potential. That’s why select roles may be eligible to participate in our Long-Term Incentive Plan (LTIP): an incentive program designed to attract, retain, and reward top talent.

What is the Long-Term Incentive Plan (LTIP)?

Long-Term Incentive Plan (LTIP): is an incentive program that typically vests over a three-year period and is tied to both individual performance and the operational success of Texas Oncology. Awards are discretionary and based on your position, performance, and potential for future career growth at Texas Oncology.

Awards are reviewed and approved during the annual compensation review. LTIP awards are subject to your continued employment through the award payment date, and are governed by the written terms and conditions of the LTIP document.

What does the Clinical Research Nurse (RN) do?

This position offers a unique and exciting opportunity to work as a nurse in oncology clinical research. As a Clinical Research Nurse, you will provide care for patients receiving cutting-edge treatments within the oncology clinic.

This position provides a variety of responsibilities while developing rewarding relationships as you manage the cancer patient throughout their journey. Texas Oncology provides opportunities for support of your professional development to include tuition reimbursement and an annual bonus for oncology certified nurses.

Working in clinical research gives you the opportunity to make a life-changing difference in the lives of patients that wouldn’t be possible without clinical trials.

The Essential Duties and Responsibilities

  • Work closely with physicians to identify and screen potential patients for clinical trial participation
  • Present trial concepts and details to oncology patients while conducting the informed consent process.
  • Assess patients for adverse events and/or changes in condition
  • Provide staff and patient education regarding the management and administration of investigational product
  • Ensure accurate and timely documentation and data entry to meet trial requirements
  • Serve as a liaison between clinic departments to ensure proper trial conduct

Qualifications

The ideal candidate for the Clinical Research Nurse (RN) will have the following background and experience:

Level 1

  • Graduate from an accredited program for nursing education required. (BSN preferred)
  • Current licensure as a registered nurse in state of practice.
  • Current BLCS or ACLS certification required.
  • Minimum 1 year of RN experience required.
  • OCN certification strongly preferred.
  • CCRC or CCRP certification preferred.
  • Oncology or Research experience preferred.

Level 2

Minimum 3 years of nursing experience required, preferably in oncology.

Level Sr

Minimum seven years of nursing experience required, preferably in oncology.

Working Conditions

The work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. There is a possible exposure to communicable diseases, toxic substances, ionizing radiation, medical preparations and other conditions common to an oncology/hematology clinic environment.

Physical Requirements

The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

Requires full range of body motion including handling and lifting patients, manual and finger dexterity, and eye-hand coordination. Requires standing and walking for extensive periods of time. Occasionally lifts and carries items weighing up to 40 lbs. Requires corrected vision and hearing to normal range.

Qualifications

Education
Bachelor degree
Experience
5+ years of experience

Certifications

OCN (preferred)

Key Skills

Oncology nursingPatient screeningAdverse event assessmentClinical trial managementOncology careBLS

Ambulatory Care Nursing — Registered Nurse Career Context

Of the 50 active Ambulatory Care Nursing listings this role was benchmarked against, 26% are remote, 54% have no call, 76% require no weekends.

The cost-of-living index for Texas is 97.1 (US average = 100; BEA Regional Price Parities (2024)). 57.7% of Texas clinicians report burnout symptoms in WeekdayDoc's Burnout Index (2026-01 data).

How many Ambulatory Care Nursing RN jobs are remote?
MeasureThis jobMarket
Work-life score7.2 / 10 · top 10% in ambulatory care nursing (rn)ranked against 374 Ambulatory Care Nursing (RN) listingslisting-based score, 0–10
Listed paynot listedAmbulatory Care Nursing RN median $90k (middle half $83k–$99k)15 comparable listings, Nov 2026
Cost of livingTexas index 97.1US average = 100BEA Regional Price Parities (2024)
Ambulatory Care Nursing RN listings in Texas24 active386 nationallylive on WeekdayDoc, Nov 2026
Work settingon-sitepeers: 26% remote · 54% no call · 76% no weekends50 benchmarked listings
Sign-on & loan repaymentnot statedTexas registered nurse listings (all specialties): 6% state a sign-on bonus (median $9k) · 4% offer loan repayment382 active listings, Nov 2026
New Ambulatory Care Nursing RN listings225 in the last 30 days186 the 30 days before (+21%)U.S., first seen on WeekdayDoc, Nov 2026
Ambulatory Care Nursing RN pay trend+18.5% vs prior quarter—through Oct 2026
Sources: WeekdayDoc live listing index (374 Ambulatory Care Nursing (RN) listings), BEA Regional Price Parities (2024); as of Nov 2026. Same values as the Weekday Verdict and Market Insights on this page.

Work-Life Balance Analysis

WeekdayDoc's proprietary algorithm rates Clinical Research Nurse (RN) at Us Oncology a 7.2 out of 10 for work-life balance — classified as very good. This places the position in the top 10% in Ambulatory Care Nursing (RN) — ranked against 374 active Ambulatory Care Nursing (RN) listings on WeekdayDoc. Contributing factors include no on-call duties, no weekend requirements.

Location & Logistics

Texas has no state income tax, which can significantly increase take-home pay compared to high-tax states.

Top Registered Nurse Jobs

43 matches · ranked by pay

Salary Distribution

42 jobs · 38 employers
12
<$100k
13
$100k-120k
12
$120k-140k
5
$140k-160k

Annual compensation range

Benefits & Perks

26 jobs
401k / retirement match
96% this job
Sign-on bonus
19%
CME allowance
19%
Loan repayment
15%
PSLF eligible
4%

Share of similar jobs offering each benefit

#1

Hospice Nurse Case Manager

By the Bay Health · Larkspur, Colorado

$65.7-$75.7/hr
#2

Registered Nurse - Case Manager w/sign-on bonus - 5403

Vantage Search Group · Twentynine Palms, California

$125k-$156k
#3

Assistant Director of Nursing - Mental Health 616

$125k-$155k
#4

Psychiatric Nurse Manager - Women's Mental Health

$150,000 a year
+ 41 more · ranked by pay

Work-life snapshot

median 4.8this job 7.2
Among the best 10% of Ambulatory Care Nursing (RN) listings for work-life

Listing-based score, 0–10, across 374 comparable listings. Shaded area = the share scoring below this one.

  • No call
  • No weekends
Us Oncology logo

About Us Oncology

Hospitals and Health Care
The Woodlands, TX
1,001-5,000 employees

Benefits & Perks

Medical Insurance
Dental Insurance
Vision Insurance
Life Insurance
Short-term Disability
Long-term Disability
Generous PTO
401k with company match

Living in Denton

Typical 3-bedroom home value
$309k
Typical market rent
$1,492/mo
Residents’ average commute
24 min
Metro price indexU.S. average = 100
103.1
State income tax
None
Sources & methodology

Sources: Zillow home values (Sep 2026), Zillow market rents (Sep 2026), U.S. Census ACS 2024 five-year.

BEA 2024 · Dallas-Fort Worth-Arlington, TX metro prices. Housing figures are city-level.

City-level figures. Not a cost-of-living guarantee.