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Genentech
Daly City, California

Senior Medical (Science) Director - Immunology (Respiratory)

Allergy & Immunology Top 25% in Allergy & ImmunologyFull-Time

Listed compensation

$198.6K - $471K

Listing transparency2 of 6 stated

Ask the employer about the work setting, call expectations and weekend coverage.

Employment & setting
Full-Time
Call expectations
Not specified
Weekends
Not specified
Posted 1mo ago · Verified live

Job Description

The Position

A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love.

The Sr. Medical Science Director/Sr. Medical Director at Genentech puts patients and science at the center of all actions. They drive medical tactics aimed at maximizing medical progress for patients. They collaborate to drive timely data generation and dissemination.

They are expected to maintain an in-depth understanding of the medical strategy and relevant clinical and payer issues, while ensuring Genentech's partners understand key trends and shifts in the external healthcare landscape. They serve as the guardian for high standards of compliance, ethics and safety.

This role is organized within a network of experts, and therefore may be performing a variety of medical activities, as needed.

The Opportunity

We are seeking a dynamic medical leader to join the US Medical Affairs Immunology Medical Network. The position will support the in line products and launch of development pipeline Roche/Genentech assets in Immunology and Respiratory.

The Sr. Medical Science Director/ Sr. Medical Director will provide exceptional clinical and scientific leadership for medical affairs activities, aiming to generate and communicate medical evidence that aids practitioners, patients, and payers in making informed health care decisions.

The successful candidate exhibits outstanding communication and leadership skills and builds strong relationships with key stakeholders.

This position will also represent the US Medical function within cross functional teams and initiatives at Genentech, within the Roche global organization, and in external customer facing engagements. In addition to strong communication skills, this position requires the ability to lead fit-for-purpose teams in a matrix environment, flexibility in prioritizing work, and a mindset to engage in purposeful partnerships to solve complex multi-disciplinary challenges.

Key Responsibilities

  • Design, execute, and monitor medical strategies, plans and tactics spanning the lifecycle
  • Provide clinically meaningful perspective for regulatory and other scientific communications
  • Clinical Study Design and Management
  • Scientific Engagement with Genentech's Internal and External Stakeholders:
  • Congress Planning and Medical/Scientific Content Communications & Review

Accountable for implementing strategy through medical tactics, tapping into the network of relevant expertise and insights

Maintaining an in-depth understanding of relevant medical strategy and clinical, patient/caregiver, payer and healthcare/market landscape

Act as a guardian for high standards of compliance, ethics and safety; putting patients at the center of all actions.

Who You Are

Required Qualifications & Experience

Advanced Clinical/Science Degree required (e. g. PharmD, PhD, MD etc.)

Minimum 7+ years of relevant biopharmaceutical industry experience. Understanding of and/or previous experience with Phase I - III and/or Phase IV drug development

Considerable experience across Medical Affairs domains including: principles and techniques of data analysis, data interpretation and assessment of clinical relevance, medical writing and reviewing, medical strategy development, external engagement planning and execution, etc.

Experience or relevant knowledge of pre-approval drug development trials and/or post-marketing medical evidence generation, including expertise in controlled and observational study designs, data analysis, and clinical/health economic interpretations

Understanding of the US health care environment including the payer landscape, marketplace factors/dynamics, evidence-based medicine tools and practices, etc.

Proven record in developing strong relationships with external stakeholders (therapeutic area experts, external organizations, etc.)

Great team player; Highly collaborative; Good interpersonal and influencing skills; Can effectively and quickly establish rapport and influence without authority

Preferred Experience

  • Clinical and scientific experience in Immunology/Respiratory
  • Experience as part of a team in medical launch

Travel Requirements

The position is located in South San Francisco. The position may require up to 35% time traveling.

The expected salary range for this position based on the primary location of South San Francisco, CA is $198,600 - 471,000. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits

Relocation benefits are not available for this job posting.

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

Requirements

Candidates must possess an advanced clinical or science degree such as a PharmD, PhD, or MD. A minimum of 7 years of biopharmaceutical industry experience with expertise in drug development and medical affairs is required.

Qualifications

Education
Doctoral or professional degree (postgraduate degree)
Experience
10+ years of experience

Key Skills

Stakeholder managementRegulatory communicationsCross-functional collaboration

Work-Life Balance Analysis

WeekdayDoc's proprietary algorithm rates Senior Medical (Science) Director - Immunology (Respiratory) at Genentech a 7.2 out of 10 for work-life balance — classified as very good. This places the position in the top 25% in Allergy & Immunology — ranked against 59 active Allergy & Immunology listings on WeekdayDoc.

Allergy & Immunology — Physician Career Context

The cost-of-living index for California is 110.7 (US average = 100; BEA Regional Price Parities (2024)), so the posted ~$335k midpoint carries the purchasing power of roughly $302k in an average-cost state. 63.6% of California clinicians report burnout symptoms in WeekdayDoc's Burnout Index (2026-01 data).

Top Allergy & Immunology Jobs

7 matches · ranked by pay

Salary Distribution7 jobs

3
<$310k
2
$350k
1
$425k
1
$481k

Annual compensation range

Work-Life Balance Distribution7 jobs

0
1-2
0
3-4
1
5-6
6
7-8
0
9-10

Higher = better work-life balance

#1

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UnitedHealth Group · Southborough, Massachusetts

from $254,000
#2

Allergist - Full-Time - Beverly Hills - CSMG

Cedars-Sinai · Beverly Hills, California

$304K - $425K
#3

Allergist Physician

$300k-$350k
#4

Allergist / Immunnologist

$275K - $350K
+ 5 more · ranked by pay

Work-life snapshot

median 6.4this job 7.2
Higher than about 8 in 10 of 59 Allergy & Immunology listings

Listing-based score, 0–10. Shaded area = share of comparable listings scoring below this one.

Living in Daly City

Typical 3-bedroom home value
$1.14M≈ 5.7× annual pay
Typical market rent
$2,962/mo≈ 18% of gross pay
State income tax
Up to 13.3%
Sources & methodology

Sources: Zillow home values (Aug 2026), Zillow market rents (Aug 2026).

Ratios use this listing’s gross annual pay. Not a cost-of-living guarantee.

Genentech logo

About Genentech

Biotechnology Research
South San Francisco, California
10,000+ employees

Benefits & Perks

Discretionary annual bonus
Comprehensive benefits package