57+ Physician Assistant Jobs in South Carolina
Physician Assistant positions in South Carolina with $100K-$140K salary ranges, burnout scores, and schedule details shown upfront. Filter by no call, remote, and weekday-only.
57+ positions available
57+ Physician Assistant Jobs in South Carolina Available Now
These 7 roles pay ~$140k median with 3.0/10 median work-life balance — use these as your benchmarks.
in Urgent Care (PA)
Nurse Practitioner or Physician Assistant | Boiling Srings
Prisma Health Urgent Care
in Urgent Care (PA)
Nurse Practitioner or Physician Assistant | Scuffletown
Prisma Health Urgent Care
in Urgent Care (PA)
in Cardiology (PA)
in Cardiology (PA)
in Ob/gyn (PA)
in Physician Assistant roles
in Physician Assistant roles
Nurse Practitioner or Physician Assistant - Hospital Medicine Preoperative Clinic
MUSC
in Hospital Medicine (PA)
6.0/10
in Psychiatry (PA)
in Occupational Medicine
A physician assistant in south carolina role paying $65-$70/hr is hidden in this list.
56 more hidden below, ranked by pay and work-life.
Physician Assistant
Negotiation brief with every application
Your counter number + word-for-word script
One-time payment · dashboard + negotiation brief on every application
How South Carolina Compares for Physician Assistant Pay
South Carolina against neighboring states and the top payers, from our own physician assistant postings over the last 12 months — not a salary survey.
Physician Assistant roles in South Carolina advertise $8k below the $133k median across the 51 states we can measure, where Alaska leads at $174k.
| State | Median pay | vs SC | WLB | Listings |
|---|---|---|---|---|
| South Carolina (this page) | $126k | — | 5.4/10 | 421 |
| Alaska#1 | $174k | +$49k | 6.8/10 | 26 |
| California#2 | $165k | +$40k | 5.2/10 | 1505 |
| New Hampshire#3 | $163k | +$37k | 6.0/10 | 87 |
| South Dakota#4 | $163k | +$37k | 4.6/10 | 112 |
| Hawaii#5 | $156k | +$31k | 4.7/10 | 20 |
| Georgiaborders | $129k | +$3k | 5.0/10 | 523 |
| North Carolinaborders | $127k | +$1k | 5.4/10 | 587 |
“borders” = shares a border with South Carolina; “#n” = national pay rank among the 51 measured states.
South Carolina Jobs
57+ physician assistant positions in South Carolina
Competitive Pay
Earn $100K-$140K with benefits
Updated Daily
New positions added daily
Physician Assistant Jobs in South Carolina: Salary, Outlook & Work-Life Balance
South Carolina offers a competitive market for healthcare professionals seeking physician assistant jobs in south carolina. With 57+ open positions and salaries ranging from $88K to $146K, clinicians have strong options for career growth and work-life balance.
Every listing is evaluated using WeekdayDoc's proprietary work-life balance scoring system. Physician Assistant Jobs in South Carolina on this page have an average score of 6.9/10, with 13% with no on-call requirements, 56% with no weekends. This data helps clinicians quickly identify positions that match their lifestyle priorities without reading through hundreds of job descriptions.
Leading employers currently hiring for physician assistant jobs in south carolina include Prisma Health Urgent Care, MUSC, Carolina Health Specialists, Lexington Medical Center, and more. Positions span physician assistant jobs south carolina. New jobs are added daily as healthcare organizations expand their teams.
Among the top-rated employers hiring for physician assistant jobs in south carolina, Sailor Health (score: 97.0/100), GLOBAL OUTREACH TELEREHABILITATION (score: 96.8/100), Talkiatry (score: 96.4/100) have earned WeekdayDoc's Top Employer designation based on our proprietary ranking system. This ranking evaluates burnout scores (40%), salary competitiveness (30%), and work-life balance features like no-call and remote options (30%). See the full rankings on our Top Employers page.
According to WeekdayDoc's Market Pulse — which tracks real-time compensation data from thousands of active job postings — the current median salary is $107K, trending up 1.3% over the past quarter. This data is derived from 79,590+ job postings analyzed over the past 12 months — updated daily, unlike annual survey-based reports. Explore salary trends and burnout data on our Market Pulse dashboard.
Frequently Asked Questions
How much do physician assistants earn in South Carolina?
Listed physician assistants in South Carolina on WeekdayDoc pay roughly $88K to $146K per year, with a median near $135K. Actual pay varies by specialty, setting, experience, and shift type — every listing shows its salary upfront.
Are there remote or hybrid physician assistants jobs available?
Some physician assistants roles offer remote or hybrid flexibility. You can filter for telehealth and work-from-home options, and every listing shows its remote status before you apply.
Which physician assistants jobs have the best work-life balance?
Every physician assistant role on WeekdayDoc is scored for burnout risk using call schedule, weekend and night requirements, and remote flexibility. Among current listings, 13% with no on-call and 56% with no weekends. You can sort by work-life-balance score to surface the lowest-burnout roles first.
Who is hiring physician assistants in South Carolina right now?
Employers currently hiring for physician assistant roles include Prisma Health Urgent Care, MUSC, Carolina Health Specialists, Lexington Medical Center, and others. WeekdayDoc aggregates verified openings from these and other organizations, refreshed daily.
How many physician assistant jobs in south carolina are available, and how often are they updated?
There are currently 57+ physician assistants positions in South Carolina listed, with new roles added daily as employers post them. Create a free account to compare salaries and work-life-balance scores side by side, then apply directly.
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