Location

Physician Assistant Jobs in South Dakota

There are 10 live Physician Assistant listings in South Dakota; South Dakota ranks 7th of 51 states by median advertised pay; the employers with the most openings are Avera Health (7), Sanford Health (2), CVS Health (1).

10+ positions available

Figures are computed from live listings and reviewed by WeekdayDoc’s physician-led editorial team; data as of October 21, 2026. Posted ranges, not accepted offers. How we compute this

Prioritize:

10 jobs

Avera Health logo

Nurse Practitioner or Physician Assistant | Acute Care

Avera HealthBrookings, SD

Physician Assistant
Pay not disclosed
1h ago
New
Avera Health logo

Nurse Practitioner or Physician Assistant | Neurology | Inpatient

Avera HealthSioux Falls, SD

Physician Assistant
Pay not disclosed
Yesterday
New
CVS Health logo

Nurse Practitioner [Spanish Required]

CVS HealthHermosa, SD

Physician Assistant
$96,000-$206,000
1w ago
Avera Health logo

Physician Assistant (PA-C)

Avera HealthWagner, SD

Physician Assistant
Pay not disclosed
2w ago
Avera Health logo

Nurse Practitioner or Physician Assistant | Family Medicine

Avera HealthDell Rapids, SD

Physician Assistant
Pay not disclosed
Avera Health logo

Physician Assistant

Avera HealthEureka, SD

Physician Assistant
Pay not disclosed
Exceptional Healthcare logo

Physician Assistant (ER)

Exceptional HealthcareRapid City, SD

Physician Assistant
Pay not disclosed
Fidelity Partners logo

Physician Assistant

Fidelity PartnersEmployer score · SilverNemo, SD

Physician Assistant
$58.90 per hour
8m ago
No Weekends
Avera Health logo

Nurse Practitioner or Physician Assistant | Emergency Medicine

Avera HealthYankton, SD

Physician Assistant
Pay not disclosed
1w ago
No Nights
Sanford Health logo

APP - Nurse Practitioner or Physician Assistant | General Surgery

Sanford HealthSioux Falls, SD

Physician Assistant
Pay not disclosed
30+ days ago
No Nights
Sanford Health logo

APP - Physician Assistant or Nurse Practitioner | Physical Medicine & Rehabilitation

Sanford HealthSouth Dakota

Physician Assistant
Pay not disclosed
No Nights
Avera Health logo

Nurse Practitioner or Physician Assistant | Oncology

Avera HealthPierre, SD

Physician Assistant
Pay not disclosed
No Nights

How South Dakota Compares for Physician Assistant Pay

South Dakota against neighboring states and the top payers, from our own physician assistant postings over the last 12 months — not a salary survey.

Median advertised
$150k
Pay rank
#7 of 51
Work-life balance
4.7/10 · #41
Open listings
152

Physician Assistant roles in South Dakota advertise $14k above the $136k median across the 51 states we can measure, where Alaska leads at $168k.

Physician Assistant median pay and work-life-balance score, South Dakota compared with neighboring states and the highest-paying states
StateMedian payvs SDWLBListings
South Dakota (this page)$150k—4.7/10152
Alaska#1$168k+$18k5.1/1038
Wyomingborders$149k−$1k5.1/1055
Minnesotaborders$141k−$9k5.0/10521
North Dakotaborders$139k−$11k5.5/1039
Montanaborders$131k−$19k4.8/1053
Iowaborders$117k−$33k4.7/10187
Nebraskaborders$106k−$44k4.8/1093

“borders” = shares a border with South Dakota; “#n” = national pay rank among the 51 measured states.

Physician Assistant Jobs in South Dakota: Market Overview & Work-Life Balance

The jobs loaded on this page, counted and measured by WeekdayDoc — live listings, not a salary survey. Market comparisons elsewhere on the page use their own labeled scope and period.

Live listings
10
Pay rank
7th of 51 states
Physician Assistant Jobs in South Dakota by the numbers
MeasureThis pageContext
Most openingsAvera Health (7), Sanford Health (2)—employers with the most listings on this page
Top-rated employers hiringBetterHelp (gold, 96/100), Talkiatry (gold, 95/100), Hiaah (gold, 95/100)Top Employers work-life index

Sources: WeekdayDoc live listing index, Top Employers work-life index; updated Oct 21, 2026.

A few things worth knowing

About PA jobs in South Dakota.

How much do physician assistants earn in South Dakota?

A reliable salary estimate is unavailable for this sample of physician assistants. Compensation varies by role, specialty, location, and schedule. Compare employer-posted pay where disclosed, including its currency and pay period; missing pay is not estimated.

Are there remote or hybrid physician assistant jobs available?

Some physician assistants roles offer remote or hybrid flexibility. You can filter for telehealth and work-from-home options, and every listing shows its remote status before you apply.

Which physician assistant jobs have the best work-life balance?

Every physician assistant role on WeekdayDoc is scored for burnout risk using call schedule, weekend and night requirements, and remote flexibility. Among current listings, 8% with no weekends. You can sort by work-life-balance score to surface the lowest-burnout roles first.

Who is hiring physician assistants in South Dakota right now?

Employers currently hiring for physician assistant roles include Avera Health, Sanford Health, CVS Health, Exceptional Healthcare, and others. WeekdayDoc aggregates verified openings from these and other organizations, refreshed daily.

How many physician assistant jobs in South Dakota are available, and how often are they updated?

There are currently 10 physician assistants positions in South Dakota listed, with new roles added as employers post them. Job descriptions are public. Verified sign-in with Google or email gives free access to regular Apply, full search, and standard Market Insights. Saved jobs, My Search, and the dashboard also require verified sign-in. Eligible featured employer listings allow Apply without signup or email. Basic calculators are public and free; optional AI contract analysis, RVU Billing Optimizer, and Schedule Optimizer reports remain paid.