TwelveStone Health Partners logo
TwelveStone Health Partners
Knoxville, Tennessee

Nurse Practitioner (PRN) - Knoxville/Maryville Locations

Nurse PractitionerPer Diem Physician-Supervised State

Compensation

Pay not listed

The week · per this posting

Schedule not stated in this posting — no days, weekends, call or nights given.

Ask the employer about the pay range, the work setting, call expectations and time off.

Posted 56m ago · Verified live

Job Description

The TwelveStone Infusion Centers LLC, manages the Infusion needs of patient’s and maintains the continuum of care, from intake, assessment, and treatment through the completion of their visit. Our primary focus is the safe and effective administration of biologic medications (e. g., Remicade, Tysabri, etc.). On occasion there is a need for sterile dressing changes and lab draws.

We are currently hiring a PRN Nurse Practitioner for our infusion centers located in Knoxville and Maryville, TN.

This position is responsible for providing comprehensive care, including the assessment, diagnosis, treatment, management, education, health promotion and care coordination for patients and families with acute and chronic health needs in an outpatient setting.

We welcome NP's from all medical backgrounds with a positive attitude, preferably outstanding IV skills, and an active license in the states of practice.

Responsibilities Include

  • Provides patient and family centered IV infusion care.
  • Facilitates consistent, coordinated care and clear communication among all members of the healthcare team.
  • Incorporates the patient and family in care planning and treatment across settings.
  • Serves as an advocate for patients and families in navigating the health care system.

Communicates and collaborates effectively with physicians, health professionals, health related agencies, patients and families. Works effectively with multidisciplinary team members.

Promotes mutual respect and trust working within a team model.

Reviews, updates and recommends relevant medical, clinical and administrative policies, procedures and education & skills to help assure high quality patient care.

Actively participates in quality initiatives. Maintains accurate and timely records and reports, participates in patient service and program reviews.

Qualifications

Master’s degree in nursing from an accredited nursing school. Active and unrestricted Advanced Practice Registered Nurse and Registered Nurse license in the state where you practice, as well as current active board certification with ANCC or AANP. May substitute a degree and certification from NCCPA with an active, unrestricted license in the state you practice. CPR certification (BLS minimum, including hands-on/in-person assessment).

Experience: 2 years of experience as an NP or PA in a clinical setting required or 3+ years as a Registered Nurse in oncology, ER, ICU, and/or infusion center. Infusion experience is required. Must demonstrate a high degree of clinical expertise in working with patients with acute and chronic illnesses.

Functional Competencies

  • Excellent verbal, written, and electronic communication skills.
  • Outstanding organizational skills and the ability to multi-task in a fast-paced, high-energy environment
  • Initiative, creativity, problem-solving ability, adaptability, and flexibility.
  • Ability to work without direct supervision and practice autonomously.
  • Ability to collaborate with professional colleagues as necessary to provide quality care.
  • Ability to consistently present a friendly, welcoming, and professional approach to patient care.

Key Responsibilities

The Nurse Practitioner provides comprehensive patient-centered infusion care, including assessment, diagnosis, and treatment of acute and chronic health needs. They also facilitate coordinated care among the healthcare team and maintain accurate clinical records in an outpatient setting.

Qualifications

Education
Professional certificate or licensure
Experience
2+ years of experience

Key Skills

Infusion therapyPatient assessmentClinical diagnosisPatient educationBiologic medication administrationMultidisciplinary collaborationQuality improvementDocumentationPatient advocacyAcute care

Infusion — Nurse Practitioner Career Context

Of the 50 active Nurse Practitioner listings this role was benchmarked against, 36% are remote, 50% have no call, 66% require no weekends.

Nurse Practitioner pay on WeekdayDoc is up 1.8% vs. the prior quarter (through Oct 2026).

Nurse Practitioner by the numbers
MeasureThis jobMarket
Listed paynot listedNurse Practitioner median $167k (middle half $137k–$167k)13 comparable listings, Nov 2026
Cost of livingTennessee index 91.9US average = 100BEA Regional Price Parities (2024)
Nurse Practitioner listings in Tennessee266 active13,764 nationallylive on WeekdayDoc, Nov 2026
Work settingon-sitepeers: 36% remote · 50% no call · 66% no weekends50 benchmarked listings
Sign-on & loan repaymentnot statedTennessee Nurse Practitioner listings: 9% state a sign-on bonus · 2% offer loan repayment266 active listings, Nov 2026
Nurse Practitioner pay trend+1.8% vs prior quarter—through Oct 2026
Sources: WeekdayDoc live listing index, BEA Regional Price Parities (2024); as of Nov 2026. Same values as the Weekday Verdict and Market Insights on this page.

Location & Logistics

Tennessee has no state income tax, which can significantly increase take-home pay compared to high-tax states.

Top contract/1099 Nurse Practitioner Jobs

37 matches · ranked by pay

Salary Distribution

29 jobs · 28 employers
5
<$100k
2
$100k-125k
10
$125k-150k
11
$150k-175k
1
$175k

Annual compensation range

Benefits & Perks

26 jobs
401k / retirement match
92%
CME allowance
42%
Sign-on bonus
31%
Loan repayment
8%
Relocation assistance
4%

Share of similar jobs offering each benefit

#1

Full-Time Nurse Practitioner - Primary Care

CHS Recruiting · Helena, Arkansas

$150k-$175k
#2

Nurse Practitioner - Virtual Sleep - Full Time

Advocate Health · Downers Grove, Illinois

$54.9-$82.35/hr
#3

NP - Integrative Health - Duluth, MN

$121k-$169k
#4

Nurse Practitioner, Advanced Practice Provider

$78k-$169k
+ 35 more · ranked by pay

Work-life snapshot

median 6.0this job 2.8
Better work-life than 20% of Nurse Practitioner roles listings

Listing-based score, 0–10, across 13,529 comparable listings. Shaded area = the share scoring below this one.

Living in Knoxville

Typical 3-bedroom home value
$356k
Typical market rent
$1,701/mo
Residents’ average commute
20 min
Metro price indexU.S. average = 100
92.6
State income tax
None
Sources & methodology

Sources: Zillow home values (Sep 2026), Zillow market rents (Sep 2026), U.S. Census ACS 2024 five-year.

BEA 2024 · Knoxville, TN metro prices. Housing figures are city-level.

City-level figures. Not a cost-of-living guarantee.