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City of Hope
Duarte, California

Clinical Research Nurse-Lymphoma

Registered NurseIncludes callFull-Time

Compensation

Pay not listed

The week · per this posting

Ask the employer about the pay range, the work setting, weekend coverage and time off.

Posted 1mo ago · Verified live

Job Description

Join the transformative team at City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses.

City of Hope’s growing national system includes its Los Angeles campus, a network of clinical care locations across Southern California, a new cancer center in Orange County, California, and treatment facilities in Atlanta, Chicago and Phoenix.

Our dedicated and compassionate employees are driven by a common mission: To deliver the cures of tomorrow to the people who need them today.

Are you a compassionate and detail-oriented Registered Nurse passionate about advancing healthcare? Join our team as a Clinical Research Nurse, where you’ll play a vital role in guiding patients through innovative clinical trials while collaborating with a multidisciplinary team of physicians, Clinical Research Associates (CRA), pharmacists, and coordinators.

This is a unique opportunity to blend clinical expertise with research excellence—helping bring groundbreaking treatments to life while delivering exceptional patient-centered care.

What You’ll Do

Clinical Trial Patient Management

Partner with investigators to determine patient eligibility and ensure accurate documentation of clinical trial criteria

Assess, monitor, and document patient conditions, treatment responses, and changes in health status in accordance with IRB protocols

  • Coordinate care across the continuum (outpatient, inpatient, and home settings)
  • Triage patient calls and provide proactive communication and support to patients and families
  • Collaborate closely with physicians, nurse practitioners (NPs), physician assistants (PAs), pharmacists, and research teams
  • Plan and execute protocol-specific activities including randomization, assessments, treatments, and follow-ups
  • Ensure all clinical trial documentation is complete, accurate, and compliant to avoid protocol deviations
  • Support and monitor patient adherence to study protocols
  • Patient & Family Education
  • Educate patients and families on clinical trial treatments, procedures, and follow-up care
  • Provide ongoing support to ensure understanding and adherence to treatment plans

Informed Consent & Compliance

  • Ensure informed consent processes meet all regulatory requirements (IRB, FDA, institutional, and sponsor guidelines)
  • Participate in patient education during consent and escalate concerns to the Principal Investigator
  • Maintain timely and accurate documentation of consent forms
  • Protocol Oversight & Collaboration
  • Assist with study initiation, monitoring visits, and audits
  • Collaborate with research pharmacy and investigators to develop and implement protocol-specific orders
  • Promote adherence to clinical trial protocols and regulatory standards
  • Coordinate scheduling of patient visits, testing, and follow-ups
  • Educate nursing staff on protocol requirements and safe medication administration

Additional Responsibilities

  • Deliver patient-centered care in alignment with organizational policies and the California Nurse Practice Act
  • Maintain a high standard of professionalism, teamwork, and organization
  • Stay current with clinical research regulations, standards, and best practices
  • Serve as a mentor or preceptor for new staff and nursing students
  • Collaborate with internal teams and external partners including physicians, sponsors, and community resources
  • Full time 4/10's

Your Qualifications Should Include

BSN

2 or more years of experience in oncology. clinical research, research, ICU, other intensive care setting, pediatrics, case management or nurse navigation.

Human subjects protection training (can be completed after hire)

Required Certification/Licensure

Current California RN License

American Heart Association BLS Certification

  • City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location.
  • City of Hope is an equal opportunity employer.
  • To learn more about our Comprehensive Benefits, please CLICK HERE.

Key Responsibilities

The Clinical Research Nurse will manage patient care throughout clinical trials, ensuring adherence to protocols and regulatory standards. They will collaborate with a multidisciplinary team to provide patient education, monitor treatment responses, and maintain accurate clinical documentation.

Requirements

Candidates must hold a BSN and a current California RN license, along with BLS certification. A minimum of two years of experience in oncology, clinical research, or intensive care settings is required.

Qualifications

Education
Bachelor degree
Experience
2+ years of experience

Key Skills

Regulatory complianceMultidisciplinary collaboration

Ambulatory Care Nursing — Registered Nurse Career Context

Of the 50 active Ambulatory Care Nursing listings this role was benchmarked against, 28% are remote, 52% have no call, 66% require no weekends.

The cost-of-living index for California is 110.7 (US average = 100; BEA Regional Price Parities (2024)). 63.6% of California clinicians report burnout symptoms in WeekdayDoc's Burnout Index (2026-01 data).

Top Registered Nurse Jobs

50 matches · ranked by pay

Salary Distribution50 jobs · 40 employers

15
<$110k
16
$110k-130k
5
$130k-150k
10
$150k-170k
4
$170k+

Annual compensation range

Benefits & Perks42 jobs · 40 employers

401k / retirement match
83%
CME allowance
29%
Sign-on bonus
26%
Loan repayment
7%
PSLF eligible
5%

Share of similar jobs offering each benefit

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$60.27-$93.41/hr
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$56.5-$90.33/hr
#3

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+ 48 more · ranked by pay

Work-life snapshot

median 5.1this job 3.0
Better work-life than 20% of Ambulatory Care Nursing (RN) listings

Listing-based score, 0–10, across 331 comparable listings. Shaded area = the share scoring below this one.

  • Includes call

Living in Duarte

Typical 3-bedroom home value
$794k
Typical market rent
$2,778/mo
Residents’ average commute
30 min
Metro price indexU.S. average = 100
113.6
State income tax
Up to 13.3%
Sources & methodology

Sources: Zillow home values (Aug 2026), Zillow market rents (Aug 2026), U.S. Census ACS 2024 five-year.

BEA 2024 · Los Angeles-Long Beach-Anaheim, CA metro prices. Housing figures are city-level.

City-level figures. Not a cost-of-living guarantee.

City of Hope logo

About City of Hope

Hospitals and Health Care
Duarte, CA
10,000+ employees

Benefits & Perks

Comprehensive Benefits
4-day workweek (4/10s)