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City of Hope
Irvine, California

Nurse Practitioner - Supportive Care

Nurse PractitionerIncludes callIncludes weekendsFull-Time Physician-Supervised State

Listed compensation

$119k-$213k

The week · per this posting3-day week · 3×12s

Ask the employer about the work setting, nights and shift pattern, benefits and time off.

Posted 1h ago · Verified live

Job Description

Join the transformative team at City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses.

City of Hope’s growing national system includes its Los Angeles campus, a network of clinical care locations across Southern California, a new cancer center in Orange County, California, and treatment facilities in Atlanta, Chicago and Phoenix.

Our dedicated and compassionate employees are driven by a common mission: To deliver the cures of tomorrow to the people who need them today.

This role has several attractive elements for experienced APPs, including a collaborative interdisciplinary practice, meaningful inpatient oncology work, and a predictable schedule with shared call responsibilities.

Supportive Care Advanced Practice Provider (Nurse Practitioner)

We are seeking an experienced Supportive Care Advanced Practice Provider (APP) to join our collaborative Supportive Medicine team. This unique opportunity offers the chance to provide comprehensive supportive care services for hospitalized oncology patients while working alongside a highly skilled interdisciplinary team dedicated to improving quality of life across the cancer continuum.

In this role, the Nurse Practitioner will practice within standardized procedures and in partnership with a physician collaborator to deliver patient-centered care. Responsibilities include:

  • Performing comprehensive patient assessments and evaluations
  • Managing complex symptoms associated with cancer and cancer treatment
  • Leading goals-of-care and advance care planning discussions
  • Providing patient and family education and support
  • Coordinating care across multiple disciplines and care settings
  • Managing medical treatment plans to optimize quality of life and clinical outcomes

Schedule

This is a full-time position consisting of three 12-hour shifts per week, providing work-life balance while maintaining continuity of care for patients.

Additional Responsibilities Include

  • Participation in a shared night call rotation for one week per month
  • Shared weekend daytime coverage approximately one weekend every 3-4 weeks
  • Collaborative call and weekend responsibilities distributed across the Supportive Medicine provider team

This team-based approach fosters a supportive practice environment while ensuring seamless, high-quality care for hospitalized oncology patients.

If you are passionate about Supportive care, symptom management, and improving the patient and family experience throughout the cancer journey, we invite you to explore this rewarding opportunity.

Your Qualifications Should Include

  • Master's Degree, or Doctorate Degree as Nurse Practitioner
  • Three years clinical experience

Required Certification/Licensure

  • Current California RN license
  • California NP License
  • California NP Furnishing License within 6 months of hire
  • DEA within 6 months of hire
  • National NP Board Certification through accrediting body
  • Basic Life Support (BLS), CPR card through American Heart Association
  • ACLS and PALS
  • Pay range - $119,000 - $213,000

“City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location.”

City of Hope is an equal opportunity employer.

Key Responsibilities

The Nurse Practitioner will provide comprehensive supportive care services for hospitalized oncology patients, including symptom management and goals-of-care discussions. They will work within an interdisciplinary team to coordinate care and optimize clinical outcomes for patients across the cancer continuum.

Requirements

Candidates must hold a Master's or Doctorate degree as a Nurse Practitioner and possess at least three years of clinical experience. Required credentials include a California RN and NP license, NP board certification, and BLS, ACLS, and PALS certifications.

Qualifications

Education
Doctoral or professional degree (postgraduate degree)
Experience
2+ years of experience

Certifications

DEA License

Key Skills

Patient assessmentInterdisciplinary collaborationPatient educationCare coordinationMedical treatment planningClinical outcomes optimization

Oncology — Nurse Practitioner Career Context

The cost-of-living index for California is 110.7 (US average = 100; BEA Regional Price Parities (2024)), so the posted ~$166k midpoint carries the purchasing power of roughly $150k in an average-cost state. 63.6% of California clinicians report burnout symptoms in WeekdayDoc's Burnout Index (2026-01 data).

Of the 50 active Oncology listings this role was benchmarked against, 26% are remote, 52% have no call, 72% require no weekends.

What does the Oncology market look like in California?
MeasureThis jobMarket
Listed pay$119k–$213kOncology median $160k (middle half $137k–$183k)31 comparable listings, Nov 2026
Cost-of-living adjusted pay~$150k in purchasing powerCalifornia index 110.7 (US = 100)BEA Regional Price Parities (2024)
Oncology listings in California41 active283 nationallylive on WeekdayDoc, Nov 2026
Work settingon-sitepeers: 26% remote · 52% no call · 72% no weekends50 benchmarked listings
Sign-on & loan repaymentnot statedCalifornia Nurse Practitioner listings: 18% state a sign-on bonus (median $20k) · 12% offer loan repayment1,000 active listings, Nov 2026
Oncology hiring demand#10 of 19 specialtiespostings stay open a median 37 days · 5% state a sign-on bonusWeekdayDoc Hiring Index, October 2026 · 119 postings, 182 closed
New Oncology listings442 in the last 30 days391 the 30 days before (+13%)U.S., first seen on WeekdayDoc, Nov 2026
Oncology pay trend+1.4% vs prior quarter—through Oct 2026
Sources: WeekdayDoc live listing index, BEA Regional Price Parities (2024), WeekdayDoc Hiring Index; as of Nov 2026. Same values as the Weekday Verdict and Market Insights on this page.

Top Nurse Practitioner Jobs

40 matches · ranked by pay

Salary Distribution

40 jobs · 33 employers
22
<$175k
8
$175k-210k
3
$210k-245k
4
$245k-280k
3
$280k+

Annual compensation range

Benefits & Perks

36 jobs · 33 employers
401k / retirement match
92%
CME allowance
53%
Sign-on bonus
28%
Loan repayment
8%
Relocation assistance
8%

Share of similar jobs offering each benefit

#1

Nurse Practitioner Heart Failure

Sutter Health · Palo Alto, California

$205k-$297k
#2

Nurse practitioner Heart Failure & Transplant

Sutter Health · San Francisco, California

$205k-$297k
#3

Nurse Practitioner - Neuro-Oncology

$220k-$285k
#4

Family Nurse Practitioner

$182k-$274k
+ 38 more · ranked by pay

Work-life snapshot

median 5.1this job 2.4
Better work-life than 20% of Oncology (NP) listings

Listing-based score, 0–10, across 281 comparable listings. Shaded area = the share scoring below this one.

  • Includes call
  • Includes weekends

Living in Irvine

Typical 3-bedroom home value
$1.36M≈ 11.4× annual pay
Typical market rent
$3,604/mo≈ 36% of gross pay
Residents’ average commute
25 min
Metro price indexU.S. average = 100
113.6
State income tax
Up to 13.3%
Sources & methodology

Sources: Zillow home values (Sep 2026), Zillow market rents (Sep 2026), U.S. Census ACS 2024 five-year.

BEA 2024 · Los Angeles-Long Beach-Anaheim, CA metro prices. Housing figures are city-level.

Ratios use this listing’s gross annual pay. Not a cost-of-living guarantee.