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Astra Zeneca
Boston, Massachusetts · Hybrid

Medical Director, Clinical Development Neurology

Medical AffairsFull-Time

Listed compensation

$250k-$375k

The week · per this posting · weekdays assumed

Ask the employer about call expectations, weekend coverage, nights and shift pattern and time off.

Posted 34m ago · Verified live

Job Description

This Is What You Will Do

The Medical Director, Clinical Development, may lead or support the clinical subteam and the global program team to construct global clinical development plans and contribute to the development of asset level and therapeutic area strategies. This role is part of the Cell Therapy team and reports to the Senior Medical Director, Hematology.

You Will Be Responsible For

The design and execution of multiple clinical studies or clinical programs

Represent Clinical Development on the Global Program Team (GPT) and in presentations at management and review committees (e. g., Clinical Document Review Committee, Development and Commercial Steering Committee)

Work with one or more clinical study teams in the preparation of clinical study related documents including protocols, charters, statistical summary reports, meeting presentations, publications, and clinical sections of regulatory documents

Select appropriate advisory board participants and guide the team in preparation for meetings

Critically evaluate available information about diseases of interest to the therapeutic area and the competitive landscape and synthesize information succinctly to support dissemination and incorporation into clinical development programs, asset plans and therapeutic area strategy

You will need to have:

  • MD, preferably Neurologist or international equivalent is required
  • 3+ years of clinical experience preferably within industry.
  • Experience as a medical monitor for clinical trials

Publication in Peer Reviewed Journals

The duties of this role are generally conducted in an office environment. As is typical of an office based role, employees must, with or without an accommodation to: use a computer; engage in communications via phone, video, and electronic messaging; problem resolution; engage in nonlinear thought, analysis, and dialogue; collaborate; maintain general availability during standard business hours

We would prefer for you to have:

Board Certification

  • Knowledge of the assigned therapy area with the capability to interpret, discuss and represent trial or program level data.
  • 5+ years of industry experience in clinical development
  • Experience for medical responsibilities on a cross-functional team
  • Basic statistical knowledge
  • Understanding of general (and specific) therapeutic principles

Experience Designing Industry Sponsored Clinical Trials

Broad experience in the principles of clinical trial methodology, statistics, data analysis and interpretation

Experience authoring study essential documents, Clinical Study Reports, and regulatory documents

Working at Alexion

We’re inspired to think differently, to create better outcomes.

By creating an unparalleled employee experience, our organization is equipped to adapt and enrich employees with a productive, engaging, and enjoyable work experience, while accelerating world-class leadership and innovation capabilities that can deliver on our mission.

Each of us is accountable for delivering innovative medicines and supportive technology with integrity so we can truly understand and better the lives of people affected by rare diseases.

Together, we can transform lives every day The Highest Standards By operating with the highest standards of ethics and integrity, we aspire to live up to the expectations of patients, physicians, and ourselves, and to earn trust in our communities. Diversity We encourage diversity of backgrounds and ideas.

We genuinely care for and respect each other, working together as a high-performing team to deliver extraordinary results while embracing different perspectives. Dedication The dedication and passion of our employees enable us to stay focused on what matters most.

We push ourselves to achieve the highest level of medical innovation, and to redefine what it means to live with a rare disease. In-Office Hybrid This role has an expectation of working in the office a minimum of 3 days a week.

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. Inperson working give us the platform we need to connect, work at pace and challenge perceptions. That’s why we work, on average, a minimum of three days per week from the office.

But that doesn’t mean we’re not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics.

We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

Alexion is proud to be an Equal Employment Opportunity and Affirmative Action employer. We are committed to fostering a culture of belonging where every single person can belong because of their uniqueness.

The Company will not make decisions about employment, training, compensation, promotion, and other terms and conditions of employment based on race, color, religion, creed or lack thereof, sex, sexual orientation, age, ancestry, national origin, ethnicity, citizenship status, marital status, pregnancy, (including childbirth, breastfeeding, or related medical conditions), parental status (including adoption or surrogacy), military status, protected veteran status, disability, medical condition, gender identity or expression, genetic information, mental illness or other characteristics protected by law.

The annual base pay for this position ranges from 249,827.20 - 374,740.80 USD Annual. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i. e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.

28-Oct-2026

10-Nov-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

Key Responsibilities

The Medical Director will lead clinical subteams to construct global development plans and oversee the design and execution of clinical studies. They will represent Clinical Development on global program teams and ensure the synthesis of disease-related information to support therapeutic strategies.

Requirements

Candidates must hold an MD, preferably as a Neurologist, with at least 3 years of clinical experience in the industry. Experience as a medical monitor for clinical trials and a strong background in clinical trial methodology are required.

Qualifications

Education
Doctoral or professional degree (postgraduate degree)
Experience
5+ years of experience

Key Skills

NeurologyClinical trial designMedical monitoringRegulatory document preparationCross-functional leadershipAdvisory board managementProtocol developmentCompetitive landscape analysisScientific publication

Medical Affairs — Physician Career Context

The cost-of-living index for Massachusetts is 105.8 (US average = 100; BEA Regional Price Parities (2024)), so the posted ~$312k midpoint carries the purchasing power of roughly $295k in an average-cost state. 63.2% of Massachusetts clinicians report burnout symptoms in WeekdayDoc's Burnout Index (2026-01 data).

Astra Zeneca holds silver-tier status on WeekdayDoc's Top Employers work-life index, composite score 73/100, 28 active listings.

How many Medical Affairs jobs are remote?
MeasureThis jobMarket
Work-life score4.2 / 10 · above average in medical affairsranked against 284 Medical Affairs listingslisting-based score, 0–10
Listed pay$250k–$375kMedical Affairs median $285k (middle half $276k–$306k)17 comparable listings, Oct 2026
Cost-of-living adjusted pay~$295k in purchasing powerMassachusetts index 105.8 (US = 100)BEA Regional Price Parities (2024)
Medical Affairs listings in Massachusetts93 active293 nationallylive on WeekdayDoc, Oct 2026
Sign-on & loan repaymentnot statedMassachusetts Physician listings: 17% state a sign-on bonus (median $75k) · 13% offer loan repayment625 active listings, Oct 2026
Medical Affairs pay trend−1.0% vs prior quarter—through Sep 2026
Astra Zenecasilver tier, 73/100Top Employers work-life index28 active listings
Sources: WeekdayDoc live listing index (284 Medical Affairs listings), Top Employers work-life index, BEA Regional Price Parities (2024); as of Oct 2026. Same values as the Weekday Verdict and Market Insights on this page.

Top Medical Affairs Jobs

2 matches · ranked by pay
#1

Medical Monitor (US Board-Certified Psychiatrist)

PSI CRO · Remote - Nationwide

#2

Sr. Medical Director (Neurologist)

Allucent · Remote - Nationwide

Work-life snapshot

median 3.0this job 4.2
Better work-life than 60% of Medical Affairs listings

Listing-based score, 0–10, across 284 comparable listings. Shaded area = the share scoring below this one.

  • Hybrid
  • Remote
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About Astra Zeneca

Pharmaceutical Manufacturing
Cambridge, Cambridgeshire
10,000+ employees

Benefits & Perks

Health Insurance
Dental
Vision
401k
Paid Time Off
Short-term Incentive Bonus
Equity Awards