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Rochester Regional Health
Rochester, New York

Infectious Disease Nurse Practitioner - Inpatient | No Weekends | No Call

Nurse PractitionerNo callNo weekendsFull-Time Physician-Supervised State

Listed compensation

$100k-$150k

The week · per this posting · Monday – Friday

Ask the employer about the work setting and nights and shift pattern.

Posted 19m ago · Verified live

Job Description

Join a collaborative and experienced Infectious Disease team in a fully inpatient Advanced Practice Provider role supporting patients at Rochester General Hospital and Unity Hospital. This is an excellent opportunity for an APP interested in complex inpatient medicine and infectious disease while enjoying an exceptional work-life balance with a Monday-Friday daytime schedule, no call, and no weekends.

You’ll work alongside Infectious Disease physicians and an experienced APP team with 15+ years of experience, providing comprehensive care to hospitalized patients with a variety of acute and complex infectious conditions.

  • STATUS: Full Time
  • LOCATION: Rochester General Hospital & Unity Hospital
  • DEPARTMENT: Infectious Disease
  • SCHEDULE: Monday-Friday, 8:00 AM-4:00 PM | No Call | No Weekends

What Makes This Opportunity Stand Out

  • 100% inpatient Infectious Disease
  • Monday-Friday, 8:00 AM-4:00 PM
  • No call
  • No weekends
  • Collaborative physician and APP team
  • Experienced APP team with 15+ years of experience
  • Opportunity to care for medically complex patients and build specialized expertise in Infectious Disease
  • Internal Medicine experience preferred

Key Responsibilities

  • Provide comprehensive care to hospitalized patients as part of the Infectious Disease team.
  • Perform advanced patient assessments, develop differential diagnoses, and establish individualized plans of care.
  • Order and interpret laboratory testing, imaging, and other diagnostic studies as appropriate.
  • Collaborate closely with Infectious Disease physicians, APPs, hospitalists, nursing, and other interdisciplinary care teams.
  • Manage treatment plans and prescribe medications and therapies within scope of practice.
  • Monitor patient progress and adjust plans of care based on clinical findings and response to treatment.

Provide education and guidance to patients and families regarding diagnoses, treatment plans, and ongoing care.

Participate in quality improvement initiatives, continuing education, and the education of students when applicable.

Practice with a high level of clinical autonomy while having the support of an experienced Infectious Disease team.

  • OFFERINGS
  • Lucrative compensation
  • Paid malpractice with tail coverage
  • Additional benefits; Relocation services
  • 4 weeks of vacation, 1 week of CME
  • Comprehensive health benefits

Education

MS: Nursing (Required)

Licenses / Certifications

NP - Nurse Practitioner Certification - NYS Office of Professions, RN - Registered Nurse - NYS Office of Professions

Physical Requirements

Moderate - Clinical - Moderate clinical roles are patient facing roles that require continual movement, including standing, walking, and lifting 20–50 lbs., along with pushing and pulling medical equipment and assisting with patient positioning.

Employees perform frequent bending, twisting, and reaching while completing fine motor tasks in busy or confined clinical environments. High sensory acuity is essential for monitoring patient status and responding to alarms or safety concerns.

Emotional and cognitive demands are substantial, involving decision-making under pressure, responding to emergencies, and maintaining sustained focus. Environmental exposures include infectious agents, bodily fluids, chemicals, and radiation. TB testing, mask-fit testing, and physical exams are common requirements.

For disease specific care programs refer to the program specific requirements of the department for further specifications on experience and educational expectations, including continuing education requirements.

Any physical requirements reported by a prospective employee and/or employee’s physician or delegate will be considered for accommodations.

Pay Range

$100,000.00 - $150,000.00

City

Rochester

Postal CODE

14621

The posted pay range is a good faith representation of potential base pay for this position. It may be modified in the future and eligible for additional pay components. Individual annual salaries/hourly rates could vary based on position details and FTE. Pay is determined by considering factors including, but not limited to, experience, relevant qualifications, specialty, internal equity, locations, and contracts.

Rochester Regional Health is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, creed, religion, sex (including pregnancy, childbirth, and related medical conditions), sexual orientation, gender identity or expression, national origin, age, disability, predisposing genetic characteristics, marital or familial status, military or veteran status, citizenship or immigration status, or any other characteristic protected by federal, state, or local law.

Requirements

Requires a Master of Science in Nursing and current New York State Nurse Practitioner and Registered Nurse certifications. Candidates should have experience in internal medicine and the ability to work in a fast-paced, inpatient clinical environment.

Qualifications

Experience
5+ years of experience

Key Skills

Patient assessmentDifferential diagnosisTreatment planningMedication managementDiagnostic interpretationInterdisciplinary collaborationPatient educationInpatient care

Infectious Disease — Nurse Practitioner Career Context

The cost-of-living index for New York is 107.9 (US average = 100; BEA Regional Price Parities (2024)), so the posted ~$125k midpoint carries the purchasing power of roughly $116k in an average-cost state. 64.6% of New York clinicians report burnout symptoms in WeekdayDoc's Burnout Index (2026-01 data).

Of the 40 active Infectious Disease listings this role was benchmarked against, 30% are remote, 75% have no call, 75% require no weekends.

What does the Infectious Disease market look like in New York?
MeasureThis jobMarket
Work-life score7.0 / 10 · above average in nurse practitioner rolesranked against 13,529 Nurse Practitioner roles listingslisting-based score, 0–10
Listed pay$100k–$150kInfectious Disease median $133k (middle half $125k–$192k)15 comparable listings, Nov 2026
Cost-of-living adjusted pay~$116k in purchasing powerNew York index 107.9 (US = 100)BEA Regional Price Parities (2024)
Infectious Disease listings in New York1,025 active13,699 nationallylive on WeekdayDoc, Nov 2026
Work settingon-sitepeers: 30% remote · 75% no call · 75% no weekends40 benchmarked listings
Sign-on & loan repaymentnot statedNew York Nurse Practitioner listings: 11% state a sign-on bonus (median $10k) · 9% offer loan repayment1,000 active listings, Nov 2026
Infectious Disease hiring demandnot ranked this monthpostings stay open a median 36 daysWeekdayDoc Hiring Index, October 2026 · 4 postings, 25 closed
New Infectious Disease listings37 in the last 30 days33 the 30 days before (+12%)U.S., first seen on WeekdayDoc, Nov 2026
Sources: WeekdayDoc live listing index (13,529 Nurse Practitioner roles listings), BEA Regional Price Parities (2024), WeekdayDoc Hiring Index; as of Nov 2026. Same values as the Weekday Verdict and Market Insights on this page.

Work-Life Balance Analysis

WeekdayDoc's proprietary algorithm rates Infectious Disease Nurse Practitioner - Inpatient | No Weekends | No Call at Rochester Regional Health a 7.0 out of 10 for work-life balance — classified as very good. This places the position in the Above average in Nurse Practitioner roles — ranked against 13,529 active Nurse Practitioner roles listings on WeekdayDoc. Contributing factors include no on-call duties, no weekend requirements.

Top Nurse Practitioner Jobs

31 matches · ranked by pay

Salary Distribution

31 jobs · 23 employers
8
<$145k
3
$160k
9
$165k-185k
8
$185k-205k
3
$205k+

Annual compensation range

Benefits & Perks

24 jobs · 23 employers
401k / retirement match
88%
Sign-on bonus
54%
Loan repayment
38%
CME allowance
38% this job
Relocation assistance
4% this job

Share of similar jobs offering each benefit

#1

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$155k-$217k
#2

Chief Nurse Practitioner

Weill Cornell Medical College · New York, New York

$180k-$214k
#3

Clinic Director - Physician Assistant (PA-C) or Nurse Practitioner (NP)

$210k
#4

Remote Psychiatric Nurse Practitioner - Fee For Service

$141k-$203k
+ 29 more · ranked by pay

Work-life snapshot

median 6.0this job 7.0
Better work-life than 70% of Nurse Practitioner roles listings

Listing-based score, 0–10, across 13,529 comparable listings. Shaded area = the share scoring below this one.

  • No call
  • No weekends
Rochester Regional Health logo

About Rochester Regional Health

Hospitals and Health Care
Rochester, New York
10,000+ employees

Benefits & Perks

Paid malpractice with tail coverage
Relocation services
4 weeks vacation
1 week CME
Comprehensive health benefits

Living in Rochester

Typical 3-bedroom home value
$240k≈ 2.4× annual pay
Typical market rent
$1,454/mo≈ 17% of gross pay
Residents’ average commute
19 min
Metro price indexU.S. average = 100
97.0
State income tax
Up to 10.9%
Sources & methodology

Sources: Zillow home values (Sep 2026), Zillow market rents (Sep 2026), U.S. Census ACS 2024 five-year.

BEA 2024 · Rochester, NY metro prices. Housing figures are city-level.

Ratios use this listing’s gross annual pay. Not a cost-of-living guarantee.