Senior Director, Safety Physician
Listed compensation
$276k-$310k
Confirm guaranteed pay, incentives and eligibility with the employer.
- Employment & setting
- Full-Time · on-site
- Call expectations
- Not specified
- Weekends
- Not specified
Job description
Join Amylyx Pharmaceuticals as a Senior Director, Safety Physician – Remote, $276K-$310K in Cambridge, Massachusetts, United States. Amylyx has an audacious mission to usher in a new era for treating diseases with high unmet needs. Where others see challenges, we see opportunities that we pursue with urgency, rigorous science, and unwavering commitment to the communities we serve.
Benefits & Compensation
- Salary: $276K - $310K
- Health insurance coverage
- Travel to Cambridge, MA several times per year
Work Schedule
- Full-Time position.
- On-site position.
- Remote work within US (excluding AK, AZ, HI, MI, TN)
This position offers competitive compensation. Work with Amylyx Pharmaceuticals in Cambridge, Massachusetts, United States.
Key Responsibilities
The Senior Director, Safety Physician provides medical and scientific leadership for the evaluation of the safety profile and benefit-risk of investigational and commercial products. They oversee safety data throughout the product lifecycle, including clinical development, regulatory submissions, and post-marketing surveillance.
Requirements
Candidates must hold a medical degree (MD, DO, or equivalent) and have 10+ years of relevant experience in medicine, drug development, or pharmacovigilance. Strong expertise in global safety regulations and the ability to communicate complex medical information to diverse audiences are required.
Qualifications
- Education
- Doctoral or professional degree (postgraduate degree)
- Experience
- 10+ years of experience
Certifications
Key Skills
Pharmacovigilance — Physician Career Context
In Massachusetts, the Physician weighted monthly median benchmark on WeekdayDoc is ~$285k (400 salary observations; 565 listings), vs ~$290k nationally (11,381 salary observations; 28,666 listings). Monthly aggregates cover 2025-11-01 through 2026-09-01; these are not the modal's selected comparable-job medians.
Physician pay on WeekdayDoc is up 8.4% vs. the prior quarter (through Aug 2026).
The cost-of-living index for Massachusetts is 105.8 (US average = 100; BEA Regional Price Parities (2024)), so the posted ~$293k midpoint carries the purchasing power of roughly $277k in an average-cost state. 63.2% of Massachusetts clinicians report burnout symptoms in WeekdayDoc's Burnout Index (2026-01 data).
Position Insights
AI ANALYSISThis role scores 1.5/10 on work-life balance for Pharmacovigilance roles.
Career trajectory: This position offers advancement within 2-3 years. The compensation analysis shows this employer pays...
Benefits analysis: Compared to 55 similar roles, this listing's benefits package ranks...
Work-life snapshot
Listing-based score
A signal to investigate—not a guarantee about the workplace.
- On-site