Pays $272k-$302k — $10k below the Medical Affairs market median of ~$312k (22 jobs)
Medical Director, Clinical Development
About the Role
Clinical development medical director. Gene therapy. $272K-$302K. Cambridge, MA.
Join Prime Medicine as a Medical Director, Clinical Development – Gene Therapy in Cambridge, Massachusetts, United States.
Benefits & Compensation
- Salary: $272K - $302K
- Medical
- Dental
- Vision
- Life insurance
- 401(k) match
- Equity programs
- Generous paid time off
- Wellness days
- Company-wide recharge breaks
Work Schedule
- Full-Time position.
- No explicit call, weekend, or night shift information provided.
Apply to join Prime Medicine as a Medical Director, Clinical Development – Gene Therapy.
Key Responsibilities
The Medical Director will lead clinical development programs from pre-clinical stages through human proof-of-concept by designing and executing clinical trial protocols. They will also serve as a medical monitor, interface with regulatory bodies, and collaborate with cross-functional teams to advance gene editing therapies.
Requirements
Candidates must hold an M.D. or M.D.-PhD degree with at least 3 years of industry or academic experience in clinical trials or relevant research. A strong background in gene therapy, genetics, and immunology is required, with a preference for specialization in Pulmonology or Hepatology.
Qualifications
- Education
- Doctoral or professional degree (postgraduate degree)
- Experience
- 2+ years of experience
Key Skills
Medical Affairs — Physician Career Context
The cost-of-living index for Massachusetts is 105.8 (US average = 100; BEA Regional Price Parities (2024)), so the posted ~$287k midpoint carries the purchasing power of roughly $271k in an average-cost state. 63.2% of Massachusetts clinicians report burnout symptoms in WeekdayDoc's Burnout Index (2026-01 data).
Position Insights
AI ANALYSISThis role scores 3.0/10 on work-life balance for Medical Affairs roles.
Career trajectory: This position offers advancement within 2-3 years. The compensation analysis shows this employer pays...
Benefits analysis: Compared to 22 similar roles, this listing's benefits package ranks...
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