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Mayo Clinic
Rochester, Minnesota

Nurse Practitioner or Physician Assistant - Medical Oncology GI Oncology – Pancreas Cancer

Nurse PractitionerIncludes callFull-Time Full Practice Authority

Listed compensation

$120K–$167K

The week · per this posting

Ask the employer about weekend coverage, nights and shift pattern and time off.

Posted 1mo ago · Verified live

Job Description

Why Mayo Clinic

Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans – to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.

  • Benefits Highlights
  • Medical: Multiple plan options.
  • Dental: Delta Dental or reimbursement account for flexible coverage.
  • Vision: Affordable plan with national network.
  • Pre-Tax Savings: HSA and FSAs for eligible expenses.
  • Retirement: Competitive retirement package to secure your future.

Responsibilities

Join the Gastrointestinal Oncology Care Team as a Nurse Practitioner or Physician Assistant specializing in pancreatic cancer. In this challenging and rewarding role, you will build meaningful relationships with patients and families, help guide them through complex treatment decisions, and contribute to highly coordinated, multidisciplinary cancer care.

The Nurse Practitioner (NP) or Physician Assistant (PA) will be an integral part of our adult Medical Oncology outpatient practice, seeing adult patients with gastrointestinal malignancies as part of our GI care teams.

NPs and PAs see patients at initial consultation and follow established patients, guiding them through their treatment plan in close collaboration with medical oncologists.

The NP or PA manages treatment-related toxicities for patients who are going through standard and research-based cancer treatments including chemotherapy, immunotherapies, and targeted therapies.

The role spans curative-intent treatment, survivorship, evaluation of treatment response or disease progression, clinical trial enrollment, symptom management, and end-of-life care. This breadth makes the work both clinically demanding and deeply meaningful.

This role is well suited for an NP or PA who is energized by complex oncology care and values continuous learning. The successful candidate will bring strong communication, teamwork, clinical assessment, and critical-thinking skills while developing deep expertise in pancreatic and gastrointestinal cancers.

The individual NP or PA will work within the GI Oncology Tumor Group. The GI group has 6 care teams comprising Consultants, NPs, PAs, RNs, and other allied health professionals.

These teams are subdivided into the following subspecialty focus areas: Colorectal, Gastroesophageal, Pancreatic, Hepatobiliary, and Neuroendocrine cancers, with the goal of streamlining patient care and clinical trial enrollment. There is cross coverage to provide support to patients with all GI malignancies.

The teams work in close collaboration with colleagues from Gastroenterology, Surgery, Radiation Oncology, Palliative Care, and other multidisciplinary teams.

The NP or PA will have a central role on the team to provide continuity for patients, serve as a provider resource for nursing, and help with coordination of care across multidisciplinary teams. Our NPs and PAs are true experts in their areas of focus.

Once established clinically, the oncology team is very supportive of mentoring NP PAs in other academic and research pursuits. We take pride in working with individuals to identify their professional development interests and foster them. We strive to see our Advanced Practitioners excel in clinical practice, research, and education shields.

If you are drawn to complex clinical decision-making, meaningful patient relationships, collaborative practice, and the opportunity to become an expert in GI oncology, we encourage you to apply. Oncology experience is valued, but motivated candidates with strong clinical skills and a commitment to learning will be supported as they grow into the role.

Qualifications

Masters-prepared graduate of an accredited school of nursing and Nurse Practitioner program. Current Minnesota RN license and certification (or eligible to be certified) as a FNP, ANP, or ACNP (certification must be obtained within 6 months of employment date). Must be eligible for DEA registration and billing privileges. or

Graduate of accredited Physician Assistant program with current PA certification by NCCPA and registration as a PA by the Minnesota Board of Medical Practice (or eligible). Must be eligible for DEA registration and billing privileges.

External and Internal candidates for this position are asked to attach 2-3 letters of reference to their online application to be considered for this position.

New graduates please upload 3 letters of reference from preceptors that can attest to your clinical abilities.

Mayo Clinic employees applying for this position are asked to attach 3 most recent performance evaluations to online application to be considered for this position.

Site Description

Just as our reputation has spread beyond our Minnesota roots, so have our locations.

Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations.

Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is.

Equal Opportunity

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law". Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.

Qualifications

Education
Master's degree (postgraduate degree)
Experience
2+ years of experience

Certifications

DEA License

Key Skills

Treatment planningMultidisciplinary collaborationChemotherapy managementImmunotherapyTargeted therapy

Oncology — Nurse Practitioner Career Context

Mayo Clinic ranks #2 of 11 employers hiring Nurse Practitioner on WeekdayDoc by average advertised pay.

In Minnesota, the Nurse Practitioner weighted monthly median benchmark on WeekdayDoc is ~$143k (60 salary observations; 104 listings), vs ~$138k nationally (1,960 salary observations; 6,195 listings). Monthly aggregates cover 2025-12-01 through 2026-09-01; these are not the modal's selected comparable-job medians.

Of the 46 active Nurse Practitioner listings this role was benchmarked against, 33% are remote, 67% have no call, 63% require no weekends.

The cost-of-living index for Minnesota is 98.6 (US average = 100; BEA Regional Price Parities (2024)), so the posted ~$144k midpoint carries the purchasing power of roughly $146k in an average-cost state. 63.4% of Minnesota clinicians report burnout symptoms in WeekdayDoc's Burnout Index (2026-01 data).

Top Nurse Practitioner Jobs

25 matches · ranked by pay

Salary Distribution25 jobs · 15 employers

12
<$140k
5
$140k-155k
4
$155k-170k
2
$170k-185k
2
$185k+

Annual compensation range

Benefits & Perks21 jobs · 15 employers

401k / retirement match
100% this job
CME allowance
67% this job
Sign-on bonus
33%
Loan repayment
10%
Relocation assistance
10%

Share of similar jobs offering each benefit

#1

In-Home Health - Nurse Practitioner or Physician Assistant (Full Time) - Minneapolis, MN

CVS Health · Minnesota

$87k-$187k
#2

Telehealth Nurse PractitionerContract

Urrly · Los Angeles, California

$156k-$187k
#3

Outpatient PMHNP – Child & Adolescent

$174k
#4

Medical Director - FNP

$153k-$172k
+ 23 more · ranked by pay

Work-life snapshot

median 5.1this job 3.9
Better work-life than 30% of Oncology (NP) listings

Listing-based score, 0–10, across 271 comparable listings. Shaded area = the share scoring below this one.

  • On-site
  • Includes call

Living in Rochester

Typical 3-bedroom home value
$307k≈ 2.6× annual pay
Typical market rent
$1,650/mo≈ 17% of gross pay
Residents’ average commute
17 min
Metro price indexU.S. average = 100
90.8
State income tax
Up to 9.8%
Sources & methodology

Sources: Zillow home values (Aug 2026), Zillow market rents (Aug 2026), U.S. Census ACS 2024 five-year.

BEA 2024 · Rochester, MN metro prices. Housing figures are city-level.

Ratios use this listing’s gross annual pay. Not a cost-of-living guarantee.

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About Mayo Clinic

Hospitals and Health Care
Rochester, Minnesota
10,000+ employees

Benefits & Perks

Medical insurance
Dental insurance
Vision insurance
Pre-tax savings (HSA, FSA)
Retirement package