Oncology & Infusion Nurse Practitioner
Listed compensation
$100-$120/hr
The week · per this posting
Schedule not stated in this posting — no days, weekends, call or nights given.
Ask the employer about call expectations, weekend coverage, nights and shift pattern and time off.
Job Description
*Required*
California Specialty Pharmacy: Job Description
Oncology & Infusion Nurse Practitioner – Per Diem, Fresno, CA
Description of Responsibilities
The Oncology & Infusion Nurse Practitioner is responsible for providing advanced clinical care and clinical oversight for patients receiving chemotherapy, immunotherapy, targeted therapies, biologic therapies, supportive medications, and other specialty infusion therapies at the Fresno clinic.
The Nurse Practitioner conducts comprehensive patient assessments, evaluates treatment readiness, reviews clinical and laboratory parameters, manages treatment-related adverse events and infusion reactions, and collaborates with physicians, pharmacists, and nursing staff to promote safe, evidence-based care.
The role also supports patient education, accurate documentation, quality improvement, staff clinical guidance, and compliance with organizational policies and applicable regulatory standards.
Reporting Relationship
Director of Nursing or designee
Scope of Supervision
Provides clinical oversight and guidance to infusion nursing and pharmacy staff. No direct personnel supervision unless assigned by leadership.
Responsibilities of the Oncology & Infusion Nurse Practitioner include the following:
- Performs comprehensive initial and ongoing patient assessments, including history, physical examination, medication review, symptom evaluation, and review of relevant clinical information.
- Evaluates patient readiness for treatment and confirms that ordered treatment parameters have been met before therapy begins.
- Reviews laboratory values, diagnostic results, treatment protocols, body surface area calculations, dosing, and provider authorization, as applicable, before chemotherapy administration.
- Provides clinical oversight for the safe administration of chemotherapy, immunotherapy, targeted therapies, biologic therapies, supportive medications, hydration, and other specialty infusion therapies.
- Administers ordered therapies within the Nurse Practitioner scope of practice, approved privileges, provider orders, manufacturer recommendations, evidence-based guidelines, and organizational policies.
- Collaborates with the treating physician and pharmacist regarding treatment plans, dose modifications, supportive care, contraindications, precautions, and changes in patient condition.
- Assesses, identifies, and manages treatment-related adverse events, toxicities, hypersensitivity reactions, anaphylaxis, extravasation, and other infusion-related complications.
- Initiates appropriate interventions during an adverse event, including stopping or pausing treatment, providing emergency or supportive care within scope, notifying the physician and pharmacist, and escalating to emergency services or a higher level of care when indicated.
- Reassesses the patient following clinical intervention and documents the event, interventions performed, notifications made, patient response, and disposition.
- Provides on-site clinical consultation and support to infusion nurses regarding patient assessment, symptom management, treatment parameters, adverse event response, and escalation of care.
- Ensures independent double-check processes are completed for chemotherapy and other high-alert medications in accordance with organizational requirements.
- Promotes compliance with hazardous drug handling requirements, required personal protective equipment, spill response procedures, and applicable USP <800>, OSHA, NIOSH, and organizational standards.
- Assesses and manages venous access devices, including implanted ports, PICCs, central venous catheters, and peripheral IVs, within scope and according to organizational policy and applicable infusion standards.
- Observes and evaluates patients before, during, and after therapy for therapeutic response, side effects, adverse reactions, and changes in condition.
- Provides education to patients and caregivers regarding the treatment plan, expected side effects, self-monitoring, symptom management, safety precautions, and when to contact the care team or seek emergency care.
- Develops, evaluates, and updates the patient plan of care in collaboration with the interdisciplinary team.
- Obtains, communicates, and documents provider orders and clinical recommendations as permitted within scope of practice.
- Maintains timely, complete, and accurate documentation of assessments, treatment decisions, interventions, communications, education, and follow-up care in the electronic medical record.
- Participates in review of adverse events, medication variances, patient safety concerns, and performance improvement activities.
- Supports the development, review, and implementation of oncology and infusion policies, procedures, clinical workflows, and emergency response processes.
- Participates in staff education, competency validation, case review, clinic meetings, and ongoing training to maintain clinical expertise.
- Maintains aseptic technique, infection prevention practices, and a care environment that supports patient safety and quality.
- Adheres to organizational payroll, billing, documentation, privacy, compliance, and professional conduct requirements.
- Performs other duties within scope of practice as assigned.
Qualifications
- Master of Science in Nursing (MSN) or Doctor of Nursing Practice (DNP) from an accredited Nurse Practitioner program (required)
- Current, active, and unrestricted California Registered Nurse and Nurse Practitioner licenses in good standing (required)
- Current national board certification as a Nurse Practitioner in an applicable population focus (required)
- Current furnishing number and DEA registration when required for assigned responsibilities (required)
- Current BLS certification; ACLS certification preferred (required)
- Current ONS Chemotherapy/Immunotherapy Provider Card or completion within the timeframe established by the organization (preferred)
- Minimum two (2) years of oncology infusion experience required; outpatient infusion center experience (preferred)
- Demonstrated experience recognizing and managing chemotherapy toxicities, infusion reactions, and oncology-related adverse events (preferred)
- Knowledge of hazardous drug handling, infection prevention, medication safety, and emergency response procedures (preferred)
- Submit to required background screening and other employment requirements.
Physical Requirements
The physical requirements described here are representative of those that must be met by an employee to successfully perform the essential functions of this job description:
- Able to stand, walk, kneel, and assist patients with transfers and mobility as needed.
- Able to respond promptly during infusion reactions and other clinical emergencies.
- Vision and hearing are sufficient to perform patient assessments and safely use clinical equipment.
- Hand dexterity and strength sufficient to operate a keyboard, handle medication supplies, access vials, manage vascular access devices, and program infusion pumps.
- Able to perform the essential duties of the position with or without reasonable accommodation.
Current, active and in good standing registered nurse license in the state of employment
Key Responsibilities
The Oncology & Infusion Nurse Practitioner provides advanced clinical care and oversight for patients receiving chemotherapy and specialty infusion therapies. This role involves conducting comprehensive assessments, managing treatment-related adverse events, and collaborating with the interdisciplinary team to ensure safe, evidence-based care.
Qualifications
- Education
- Professional certificate or licensure
- Experience
- 2+ years of experience
Certifications
Key Skills
Oncology — Nurse Practitioner Career Context
The cost-of-living index for California is 110.7 (US average = 100; BEA Regional Price Parities (2024)), so the posted ~$229k midpoint carries the purchasing power of roughly $207k in an average-cost state. 63.6% of California clinicians report burnout symptoms in WeekdayDoc's Burnout Index (2026-01 data).
Of the 50 active Oncology listings this role was benchmarked against, 28% are remote, 40% have no call, 46% require no weekends.
Oncology pay on WeekdayDoc is up 5.5% vs. the prior quarter (through Sep 2026).
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