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Adams Clinical
Philadelphia, Pennsylvania

Research Nurse - Per Diem

Registered NursePer Diem

Listed compensation

$45-$55/hr

The week · per this posting

Schedule not stated in this posting — no days, weekends, call or nights given.

Ask the employer about the work setting, call expectations, weekend coverage and time off.

Posted 33m ago · Verified live

Job Description

Join Us in Shaping the Future of Clinical Research

Adams Clinical is a leading clinical trial site network committed to accelerating the development of life-changing medicines. Our mission is simple: deliver uncompromising data quality, safety, and diverse enrollment to advance healthcare. Our vision is to set the gold standard for clinical trial excellence.

We believe our people make the difference. Guided by our core values—Scientific Rigor, Operational Excellence, Commitment to Sponsors and Participants, and Authentic Collaboration—we create an environment where meaningful work drives meaningful change.

At Adams Clinical, You’ll Find

  • A culture of respect, transparency, and continuous improvement
  • Opportunities for professional growth and learning
  • A team dedicated to improving lives through innovation and integrity
  • If you’re passionate about making an impact in clinical research and want to be part of a collaborative, mission-driven organization, we’d love to have you on our team.

Job Role

Adams Clinical is seeking a PRN Nurse (RN) to provide flexible, as-needed on-site clinical support at our clinical research site located in Philadelphia. This role works under the direction of physician Principal Investigators and Clinical Operations leadership in the conduct of pharmaceutical-sponsored clinical trials in accordance with study protocols, FDA regulations, GCP guidelines, and applicable research requirements.

Typical tasks will include, but are not limited to, injections, investigational product (IP) preparation, IV catheterization and drug infusion, phlebotomy, medical record and clinical results review, medication reconciliation, and medical liaising. The ideal candidate must be comfortable working in a clinical research environment, following study protocols, and maintaining clear and timely documentation in accordance with study protocols and applicable research and regulatory requirements.

Key Responsibilities

Support the preparation and handling of investigational product (IP), as needed and as permitted by the study protocol, site procedures, and applicable requirements

Administer subcutaneous and intramuscular injections, as needed in accordance with study protocols and nursing scope of practice

IV placement, initiation and monitoring of IV infusions, as needed in accordance with the study protocol and nursing scope of practice

  • Perform phlebotomy and assist with difficult blood draws, as needed
  • Assist with collection of vital signs and other protocol-required clinical assessments, as needed

Identify and escalate clinically significant findings, changes in participant condition, and potential reactions to study dosing, including those that may impact participant safety or subsequent dosing, in collaboration with the site Principal Investigator

Review medical records and reconcile relevant information with patient-reported history in collaboration with site medical investigators

Assist with collection and documentation of adverse events (AEs), concomitant medications, and medical history

Assist with identification, documentation, and reporting of Serious Adverse Events (SAEs), including required regulatory/IRB documentation

Support participant safety and respond appropriately to urgent or emergency clinical situations within nursing scope of practice and site procedures, including assisting with crash cart supply and medication checks as needed

Document clinical procedures and participant-related information accurately and in a timely manner in accordance with study protocols and applicable requirements

Collaborate with Principal Investigators and medical sub-Investigators, Clinical Operations, Clinical Research Coordinators, and other study team members to support safe and efficient study conduct

Qualifications

  • Current and unrestricted license to practice as a Registered Nurse in the state of Pennsylvania required
  • Bachelor’s degree in nursing (BSN) required
  • 2+ years of experience as a nurse preferred
  • Recent bedside nursing experience required
  • Strong IV placement, phlebotomy, and infusion skills preferred
  • Previous clinical research experience and familiarity with GCP and FDA regulations preferred, but not required

BLS/CPR Certification Preferred

Strong attention to detail and ability to follow study protocols and established clinical procedures while maintaining clear, accurate, and timely clinical documentation

Strong communication and collaboration skills, with the ability to work effectively with Principal Investigators, sub-Investigators, Clinical Research Coordinators, and other study team members

Hours

  • This is a per diem PRN position, with hours varying on clinical and study needs.
  • Pay: $45-55/hr, commensurate with experience

Benefits

  • 401(k) matching
  • Medical, Dental & Vision insurance
  • Employee assistance program
  • Flexible spending account
  • Health insurance
  • Health savings account
  • Life insurance
  • Paid time off
  • Parental leave

Professional Development Assistance

Adams Clinical is committed to being an equal opportunity and affirmative action employer. We focus on hiring and nurturing top talent.

All employment decisions, including recruitment, hiring, promotion, compensation, transfer, training, discipline, and termination, are made based on the candidate’s or employee’s qualifications relevant to the position.

These decisions are made without regard to age, sex, sexual orientation, gender identity or expression, genetic information, race, color, creed, religion, ethnicity, national origin, citizenship, disability, marital status, military status, pregnancy, or any other legally protected status.

In compliance with federal law, all individuals hired must, as a condition of employment, provide documentation verifying their identity and authorization to work in the United States and complete Form I-9 within the required time frame. Adams Clinical participates in E-Verify to confirm employment eligibility.

Qualifications

Education
Bachelor degree

Certifications

BLS (preferred)

Key Skills

Patient assessmentAdverse event reportingClinical trial protocolsInjection administrationMedical record review

Clinical Research — Registered Nurse Career Context

Of the 40 active Registered Nurse listings this role was benchmarked against, 18% are remote, 60% have no call, 78% require no weekends.

The cost-of-living index for Pennsylvania is 97.6 (US average = 100; BEA Regional Price Parities (2024)), so the posted ~$104k midpoint carries the purchasing power of roughly $107k in an average-cost state. 61.7% of Pennsylvania clinicians report burnout symptoms in WeekdayDoc's Burnout Index (2026-01 data).

What does the Registered Nurse market look like in Pennsylvania?
MeasureThis jobMarket
Listed pay$94k–$114kRegistered Nurse median $90k (middle half $85k–$104k)31 comparable listings, Nov 2026
Cost-of-living adjusted pay~$107k in purchasing powerPennsylvania index 97.6 (US = 100)BEA Regional Price Parities (2024)
All registered nurse listings in Pennsylvania193 active5,773 nationallylive on WeekdayDoc, Nov 2026
Work settingon-sitepeers: 18% remote · 60% no call · 78% no weekends40 benchmarked listings
Sign-on & loan repaymentnot statedPennsylvania registered nurse listings (all specialties): 10% state a sign-on bonus (median $10k) · 2% offer loan repayment193 active listings, Nov 2026
Registered Nurse pay trend (all specialties)+4.6% vs prior quarter—through Oct 2026
Adams Clinicalsilver tier, 78/100Top Employers work-life index3 active listings
Sources: WeekdayDoc live listing index, Top Employers work-life index, BEA Regional Price Parities (2024); as of Nov 2026. Same values as the Weekday Verdict and Market Insights on this page. Pennsylvania figures use all registered nurses: too few Pennsylvania Clinical Research postings state pay.

Top contract/1099 Registered Nurse Jobs

40 matches · ranked by pay

Salary Distribution

27 jobs · 25 employers
11
<$125k
9
$125k-140k
4
$140k-155k
3
$155k-170k

Annual compensation range

Benefits & Perks

23 jobs
401k / retirement match
100% this job
CME allowance
26%
Loan repayment
17%
Sign-on bonus
13%

Share of similar jobs offering each benefit

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$86.6-$121.23/hr
#2

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#3

Registered Nurse (RN) Oncology Phone Triage PRN

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#4

PRN RN Case Manager - Home Health Agency | Indianapolis, IN - NOII

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+ 38 more · ranked by pay

Work-life snapshot

median 3.9this job 2.8
Better work-life than 30% of Registered Nurse roles listings

Listing-based score, 0–10, across 5,740 comparable listings. Shaded area = the share scoring below this one.

Adams Clinical logo

About Adams Clinical

Biotechnology Research
Watertown, Massachusetts
201-500 employees

Benefits & Perks

401(k) Matching
Medical Insurance
Dental
Vision
Employee Assistance Program
Flexible Spending Account
Health Savings Account
Life Insurance

Living in Philadelphia

Typical 3-bedroom home value
$203k
Typical market rent
$1,757/mo
Residents’ average commute
32 min
Metro price indexU.S. average = 100
102.6
State income tax
Up to 3.1%
Sources & methodology

Sources: Zillow home values (Sep 2026), Zillow market rents (Sep 2026), U.S. Census ACS 2024 five-year.

BEA 2024 · Philadelphia-Camden-Wilmington, PA-NJ-DE-MD metro prices. Housing figures are city-level.

City-level figures. Not a cost-of-living guarantee.