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Headlands Research
Chesterfield, Missouri

Nurse Practitioner or Physician Assistant - Clinical Research

Nurse Practitioner Above average in Nurse Practitioner rolesNo weekendsFull-Time Physician-Supervised State

Compensation

Pay not disclosed

Listing transparency2 of 6 stated

Ask the employer about the pay range, call expectations and nights and shift pattern.

Employment & setting
Full-Time · on-site
Call expectations
Not specified
Weekends
No weekends
Posted 2mo ago

Job Description

At Headlands Research, we are dedicated to enhancing clinical trial delivery within our communities. As a leading network of advanced clinical trial sites, we leverage cutting-edge technology and exceptional support services to broaden outreach and participation. Founded in 2018, our rapidly growing company currently operates 20+ sites across the US and Canada, with plans for further expansion.

Championing Diversity in Clinical Trials

Diversity isn't just a checkbox for us - it's central to our mission. We're committed to advancing medical science by promoting diversity in every facet of clinical trial research. From our team composition to participant demographics, inclusivity is at the heart of everything we do.

The Role of a Lifetime

Are you ready to make a difference? We're seeking an experienced Nurse Practitioner or Physician Assistant to help us grow our clinical research site located in the Greater St. Louis Area. You will help the site conduct clinical research trials involving gastroenterology, neurology, vaccines, and general internal medicine.

Clinical Research Professionals (CRP) is a dedicated research center that provides a network of providers who work collaboratively in conducting clinical research trials. The site’s team brings more than 20 years of experience, including many highly accomplished principal investigators across multiple therapeutic areas that are helping to improve lives through advancement of new drug therapies and medical devices.

  • Type: Full-time Regular Employee
  • Pay: Competitive and dependent upon years of experience as an Investigator in clinical research.
  • Location: Onsite in Chesterfield, MO (no opportunities for remote or hybrid)
  • Schedule: Mondays through Fridays, 8:00am-5:00pm

Responsibilities

  • Ensure the safety and welfare of each study subject
  • Have in-depth knowledge of all research protocols
  • Screen potential study subjects according to the protocol’s specific inclusion and exclusion criteria
  • Conduct medical history interviews and physical examinations throughout the subject’s study participation
  • Review EKG’s and lab results
  • Provide medical care as needed during a subject’s participation in a clinical trial
  • Provide home based on-call availability per standard policy
  • Attend Investigator Meetings on behalf of Principal Investigator as needed
  • Excellent professional communication, punctual and responsible
  • Friendly and outgoing demeanor
  • Must demonstrate a passion for direct patient interaction

Demonstrate clinical competence, positive leadership and ability to work collaboratively with a multi-disciplinary team

Qualifications

Minimum of two years of experience as a licensed family or non-acute adult nurse practitioner or physician assistant treating a wide variety of therapeutic areas for the adult and geriatric patient population required (internal medicine, family medicine, urgent care, emergency medicine)

  • Current and unencumbered license to practice as an NP or PA in the state of Missouri required
  • Prior experience within the clinical research industry required
  • Commitment and ability to deliver excellent customer service
  • Excellent communication, punctual and responsible
  • Extremely well organized
  • Excellent verbal and written communication skills
  • Trustworthy, reliable; attentive to details
  • Mature and pleasant demeanor
  • Willingness to learn new tasks and grow with the company

Headlands Research will never ask a candidate for personal identifiable information (date of birth, social security number, driver’s license information, etc) via email or messenger tools, or for a financial deposit of any kind.

Headlands Research is an Equal Opportunity Employer. We do not discriminate on the basis of race, color, religion, age, sex, national origin, disability status, genetic information, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state, or local laws.

Need Assistance?

Headlands Research is committed to providing access and reasonable accommodation in its employment for individuals with disabilities. To request disability accommodation in the application process, contact recruiting@headlandsresearch.com for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.

Qualifications

Education
Professional certificate or licensure
Experience
2+ years of experience

Key Skills

Patient ScreeningEKG ReviewLab Result AnalysisMedical History InterviewingPatient CareProtocol AdherenceCollaborationOrganizationTime Management

Work-Life Balance Analysis

WeekdayDoc's proprietary algorithm rates Nurse Practitioner or Physician Assistant - Clinical Research at Headlands Research a 6.4 out of 10 for work-life balance — classified as good. This places the position in the Above average in Nurse Practitioner roles — ranked against 13,004 active Nurse Practitioner roles listings on WeekdayDoc. Contributing factors include no weekend requirements.

Clinical Research — Nurse Practitioner Career Context

Of the 50 active Nurse Practitioner listings this role was benchmarked against, 38% are remote, 60% have no call, 86% require no weekends.

The cost-of-living index for Missouri is 90.8 (US average = 100; BEA Regional Price Parities (2024)). 60.1% of Missouri clinicians report burnout symptoms in WeekdayDoc's Burnout Index (2026-01 data).

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Annual compensation range

Benefits & Perks34 jobs

401k / retirement match
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CME allowance
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Sign-on bonus
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Loan repayment
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Relocation assistance
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Work-life snapshot

6.4/ 10
Listing-based score

Above average in Nurse Practitioner roles

  • No weekends
  • On-site

Living in Chesterfield

Typical 3-bedroom home value
$491k
Typical market rent
$1,767/mo
Residents’ average commute
22 min
Metro price indexU.S. average = 100
95.1
State income tax
Up to 5.3%
Sources & methodology

Sources: Zillow home values (Aug 2026), Zillow market rents (Aug 2026), U.S. Census ACS 2024 five-year.

BEA 2024 · St. Louis, MO-IL metro prices. Housing figures are city-level.

City-level figures. Not a cost-of-living guarantee.