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Sanford Health
Sioux Falls, South Dakota

Pharmacist – Adult Internal Medicine Focused – Overnight Rotation

PharmacistFull-Time

Listed compensation

$57-$87.5/hr

The week · per this posting · weekdays assumed

Ask the employer about the work setting, call expectations, weekend coverage and time off.

Posted 1mo ago · Verified live

Job Description

Sanford Health, the largest rural health system in the United States, is dedicated to transforming the health care experience and providing access to world-class health care in America’s heartland.

Work Shift

10 Hours - Rotating Shifts (United States of America)

Scheduled Weekly Hours

40

Compensation

Salary Range: $57.00 - $87.50

Union Position

No

Department Details

This position includes an overnight rotation every sixth week. The overnight rotation runs Tuesday through Monday for seven consecutive 10-hour shifts, from 8:30 p. m. to 6:30 a. m. Following the overnight rotation, the pharmacist is off until the subsequent Monday. The remaining four weeks of the rotation consist primarily of 8-hour day shifts, with occasional evening shifts.

Summary

During the overnight rotation, the pharmacist works closely with pharmacy technicians to provide operational oversight. The pharmacist also partners with the pediatric overnight pharmacist to provide timely medication order verification and comprehensive clinical pharmacy care throughout the hospital.

Review prescriptions to assure accuracy, to ascertain the needed ingredients, and to evaluate their suitability. Provide information and advice regarding drug interactions, side effects, dosage, and proper medication storage.

Job Description

In a medical center or institutional setting, the Pharmacist reviews and interprets provider orders, provides drug information, assists in problem solving, and provides other aspects of pharmaceutical care.

Duties may consist of unit dose dispensing, IV Admixtures, outpatient prescriptions, navigating the electronic medical record, compounding, and working with automated dispensing devices.

The Pharmacist utilizes appropriate age-related patient information to assess the pharmaceutical needs of patients, which may include provision of pharmaceutical care to neonatal, pediatric, adolescent, adult, and geriatric patients.

The Pharmacist follows all established regulations and standards that govern the practice of pharmacy. May be required to act as a shift supervisor under direct or indirect supervision by department managers. Demonstrates good written and verbal communication skills.

Must be able to learn and utilize new technology as the profession of pharmacy evolves. Provides oversight and clinical supervision for pharmacy services and pharmacy support personnel.

Pharmacy services at Sanford Health may include involvement in acute care surgery, neurology, cardiology, pediatrics, oncology, infusion services, intensive care, general medicine, dialysis, transplant, antimicrobial stewardship, and medication reconciliation.

May include decentralized clinical functions, such as direct patient interaction/interdisciplinary team rounding, chart reviews, customer or patient counseling, collecting accurate medication list.

May also include centralized clinical functions, such as checking and dispensing medications and overseeing the clinical functions of the IV room.

Qualifications

In a retail/community pharmacy setting: Graduate of an accredited School of Pharmacy. Must have a thorough knowledge of drugs and their actions; knowledge of state and local regulations. In a medical center or institutional setting: Graduate of an accredited School of Pharmacy. Must have a thorough knowledge of drugs and their actions; knowledge of state and local regulations. Hospital experience or residency preferred.

License must be in good standing by the State Board of Pharmacy in state(s) of practice and/or possess multi-state licensure privileges as required by position.

Sanford is an EEO/AA Employer M/F/Disability/Vet.

If you are an individual with a disability and would like to request an accommodation for help with your online application, please call 1-877-949-5678 or send an email to talent@sanfordhealth.org.

Key Responsibilities

The pharmacist provides operational oversight and clinical pharmacy care, including medication order verification and drug information services. They work closely with pharmacy technicians and interdisciplinary teams to ensure accurate and safe pharmaceutical care across various hospital departments.

Qualifications

Experience
2+ years of experience

Key Skills

Drug interaction analysisPharmacy operationsChart review

Internal Medicine — Pharmacist Career Context

Of the 40 active Pharmacist listings this role was benchmarked against, 55% are remote, 55% have no call, 63% require no weekends.

The cost-of-living index for South Dakota is 88.6 (US average = 100; BEA Regional Price Parities (2024)), so the posted ~$150k midpoint carries the purchasing power of roughly $170k in an average-cost state. 58.2% of South Dakota clinicians report burnout symptoms in WeekdayDoc's Burnout Index (2026-01 data).

Location & Logistics

South Dakota has no state income tax, which can significantly increase take-home pay compared to high-tax states. At the posted ~$150k midpoint, that is roughly $6k–$11k a year versus a typical 4–7% state rate.

Top Pharmacist Jobs

16 matches · ranked by pay

Salary Distribution16 jobs · 12 employers

3
<$155k
9
$155k-175k
2
$185k
2
$195k-215k

Annual compensation range

Benefits & Perks14 jobs · 12 employers

401k / retirement match
93%
Sign-on bonus
43%
Relocation assistance
7%

Share of similar jobs offering each benefit

#1

Pharmacist Clinical (Oncology)

Elevance Health · Cincinnati, Ohio

$119k-$215k
#2

Clinical Pharmacist (Formulary & Quality)

Centene · Indiana

$108k-$199k
#3

Clinical Pharmacist Specialist - Specialty (Oncology, Remote-Hybrid)- Full-Time Days

$159k-$185k
#4

Clinical Pharmacist Specialist (Adult ICU)- Full-Time Rotate

$159k-$185k
+ 14 more · ranked by pay

Work-life snapshot

median 2.8this job 3.0
Better work-life than 50% of Pharmacist roles listings

Listing-based score, 0–10, across 10,664 comparable listings. Shaded area = the share scoring below this one.

Living in Sioux Falls

Typical 3-bedroom home value
$304k
Typical market rent
$1,302/mo
Residents’ average commute
17 min
State income tax
None
Sources & methodology

Sources: Zillow home values (Aug 2026), Zillow market rents (Aug 2026), U.S. Census ACS 2024 five-year.

City-level figures. Not a cost-of-living guarantee.