Human Longevity logo
Human Longevity
South San Francisco, California

Physician Assistant

Physician AssistantNo callFull-Time

Listed compensation

$160k-$180k

The week · per this posting

Ask the employer about the work setting, weekend coverage, nights and shift pattern and time off.

Posted 6m ago · Verified live

Job Description

Join Human Longevity and be a part of revolutionizing the future of medicine!

Healthcare, reimagined. Proactive. Precise. Personalized.

About Human Longevity

At Human Longevity, our mission is to revolutionize medicine by bridging the gap between health span and life span, where our members continue to enjoy optimal health and functionality well into 100+.

We provide preventative, predictive and personalized longevity precision medicine that enhances performance and functionality. Our goal is to help our clients enjoy every facet of life by empowering them with technology input and actionable health plans.

At Human Longevity, we believe in the science behind longevity medicine, not sensationalism.

Our AI-data driven longevity platform blends data and cutting-edge science to create personalized goals for our members, delivering exceptional care all in a relaxing luxurious environment.

What Is the Opportunity?

The Physician Assistant will report to Medical Director of clinic location, with oversight by leadership of Nucleus Medical Group (medical group partnered with Human Longevity).

They will assume responsibility for a wide scope of care, including ordering and evaluating tests as well as performing treatments as clinically indicated. They will be responsible for delivering the longevity precision medicine to our members as set forth by the leadership team.

This role requires a focus on optimal proactive preventive care, longevity medicine guidance, optimization of client retention, and passion in growing our AI technology as well as furthering longevity science.

Join our team of highly trained, passionate clinicians!

What’s in It for You?

You will be working with world renowned specialists and longevity trailblazers.

From our Buck Institute partnership to our internal team of medical leaders, Human Longevity is a place where clinicians not only save lives daily, but can also thrive in knowledge-based growth, connections to community thought leaders, and scientific advancements.

As our team members are essential to the lives of our members and also to our company, you will receive the full membership advantages of Human Longevity for your own personal health as well. Our passion is in extending not just the lives of our members, but also of our team members.

What Will You Do?

The Physician Assistant will provide advanced clinical medical care in the examination, assessment, and provision of comprehensive care for our members. Our clinicians maintain a clean work environment as well as positivity towards staff and assist in tech as well as clinical developments of our company.

Clinicians also are responsible in directing and coordinating the activities of medical assistants they work with, while consulting with and taking direction from medical director. A harmonious work environment is crucial to our company. We encourage mutual learning from all of our clinicians.

Tasks and Responsibilities

Provide precision medicine-based concierge longevity care to roughly 180+ clients

As the client’s private longevity precision medicine clinician, he/she is responsible for providing client’s medical and health management services

Participate in the Nucleus Medical Group, focusing on day-to-day clinical operations and development, as well as personalized, prevention focused medical care and targeted health promotion services

Provide regular clinical support within the practice and also via telemedicine modalities (e. g. phone, email, video chat)

Provide direct clinical oversight to a group of pre-assigned clients; assure high client satisfaction and high client retention rate

Coordinate with HLI’s Care Delivery System daily to deliver medical care and to support client’s consultation services with medical specialist

Supervise a team of nurses, technologists, and clinicians in a client-centered model, help clients set health goals, and support daily clinical work

Help contribute to consolidated report development for quality control purposes

Regularly review and deliver consolidated reports to clients and develop health goals

Provide clinical management for clients in collaboration with multidisciplinary internal and external clinician partners

Assist in training and development of internal and external longevity precision care and specialist clinicians committed to delivery of genomics-based, technology-driven medicine

Minimum Qualifications (Must have)

At least three years of experience working as a primary care-oriented Physician Assistant with background in internal medicine or family practice

Have the passion and skills to delight clients with service-oriented approach and empathetic client interaction.

  • Board Certified or pending Board certification in FNP or AGNP
  • Must have or be willing (and qualified) to obtain an unrestricted medical license for California
  • Commitment to practice of science-based medicine
  • Demonstrate ability to manage, motivate, and empower diverse clinical teams
  • Interest in or relevant experience in implementation of innovative medical care models

Excellent Communication Skills

Strong leadership and team-oriented with excellent interpersonal skills.

Preferred Qualifications

  • Functional and/or Integrative Medicine training
  • Experience working in direct pay or concierge medical settings
  • Able to thrive in an often ambiguous, challenging, and fast-paced environment
  • Experience in working with early stage medical or biotech companies
  • Health coaching and behavioral change training
  • Knowledge of clinical genetics

Compensation Package

  • Competitive compensation and benefits
  • Plus Stock Options

What Do You Need to Succeed?

To ensure success, the Physician Assistant will be detail-oriented with the ability to deliver care in a compassionate manner; personalizing care that ensures optimal health and comfort. Collaboration amongst departments of services and care are crucial in our clinician’s success as well as the success of our company. We also encourage our clinicians to engage in technological and medical advancements and developments.

Human Longevity, Inc. is an equal opportunity employer

DISCLAIMER: The information on this description has been designed to indicate the general nature and level of work. It is not designed to be interpreted as a comprehensive inventory of all duties and responsibilities of an employee to this job.

Key Responsibilities

The Physician Assistant will provide precision medicine-based concierge care, including ordering tests, performing treatments, and managing health plans for members. They will also supervise clinical staff and coordinate with medical specialists to ensure high-quality, proactive longevity care.

Requirements

Candidates must have at least three years of experience in primary care, internal medicine, or family practice, along with a valid California medical license. Board certification as an FNP or AGNP is required, and experience in integrative or functional medicine is preferred.

Qualifications

Education
Professional certificate or licensure
Experience
2+ years of experience

Key Skills

Clinical assessmentPatient careTeam leadership

Work-Life Balance Analysis

WeekdayDoc's proprietary algorithm rates Physician Assistant at Human Longevity a 6.4 out of 10 for work-life balance — classified as good. This places the position in the Above average in Family Medicine (PA) — ranked against 682 active Family Medicine (PA) listings on WeekdayDoc. Contributing factors include no on-call duties.

Family Medicine — Physician Assistant Career Context

Of the 50 active Family Medicine listings this role was benchmarked against, 10% are remote, 64% have no call, 74% require no weekends.

Family Medicine pay on WeekdayDoc is up 3.7% vs. the prior quarter (through Sep 2026).

The cost-of-living index for California is 110.7 (US average = 100; BEA Regional Price Parities (2024)), so the posted ~$170k midpoint carries the purchasing power of roughly $154k in an average-cost state. 63.6% of California clinicians report burnout symptoms in WeekdayDoc's Burnout Index (2026-01 data).

Top Physician Assistant Jobs

34 matches · ranked by pay

Salary Distribution34 jobs · 28 employers

12
<$150k
7
$150k-175k
11
$175k-200k
4
$200k-225k

Annual compensation range

Benefits & Perks28 jobs

401k / retirement match
96%
CME allowance
71%
Sign-on bonus
57%
Loan repayment
18%
Relocation assistance
14%

Share of similar jobs offering each benefit

#1

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$159k-$222k
#2

Physician Assistant, Family Medicine (Limited Term,.8 FTE)

Sutter Health · Watsonville, California

$159k-$222k
#3

Nurse Practitioner or Physician Assistant Family Practice

$171k-$218k
#4

Physician Assistant- Dr. Fealy

$195k-$212k
+ 32 more · ranked by pay

Work-life snapshot

median 4.8this job 6.4
Better work-life than 70% of Family Medicine (PA) listings

Listing-based score, 0–10, across 682 comparable listings. Shaded area = the share scoring below this one.

  • No call

Living in South San Francisco

Typical 3-bedroom home value
$1.23M≈ 7.7× annual pay
Typical market rent
$4,027/mo≈ 30% of gross pay
Residents’ average commute
26 min
State income tax
Up to 13.3%
Sources & methodology

Sources: Zillow home values (Aug 2026), Zillow market rents (Aug 2026), U.S. Census ACS 2024 five-year.

Ratios use this listing’s gross annual pay. Not a cost-of-living guarantee.

Human Longevity logo

About Human Longevity

Biotechnology
South San Francisco, California
51-200 employees

Benefits & Perks

Health Insurance
Stock Options
Full Membership Advantages
Collaborative Practice Agreement Required