Overnight Clinical Research Nurse (PRN)
Compensation
Pay not listed
The week · per this posting
Ask the employer about the pay range, the work setting, call expectations and time off.
Job Description
Overnight Clinical Research Nurse I (Onsite) - Lenexa, KS
ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster.
As a values-driven organisation, integrity, collaboration, agility, and inclusion are at the heart of how we work and interact with each other, customers, patients and suppliers.
As a Clinical Research Nurse at ICON, you will play a critical role in the execution of clinical trials, providing direct patient care while ensuring the safety and well-being of research participants. This is an overnight position supporting clinical research studies involving investigational products and intensive patient monitoring.
What You Will Do
You will be responsible for delivering high-quality clinical research nursing care while supporting study protocols and participant safety during overnight operations.
Key Responsibilities Include
- Administer investigational products according to study protocols and physician orders.
- Monitor research participants during dosing procedures and throughout study participation.
Identify, assess, document, and report adverse events and other safety findings in accordance with study protocols and regulatory requirements.
Perform clinical assessments, vital signs collection, sample collection, and other protocol-required procedures.
Collaborate with physicians, research staff, and multidisciplinary teams to ensure protocol compliance and participant safety.
Accurately document study activities and maintain research records in accordance with Good Clinical Practice (GCP) guidelines.
- Educate and support study participants throughout their clinical trial experience.
- Support overnight clinical operations while maintaining a high standard of patient care and data quality.
Your Profile
You will bring relevant nursing and clinical research experience, along with the following qualifications and skills:
Required Qualifications and Experience
- Associate's or Bachelor's degree in Nursing or a healthcare-related field.
- Active Registered Nurse (RN) license in good standing.
- Clinical research experience or experience working in a regulated healthcare environment preferred.
- Knowledge of clinical trial processes, regulatory requirements, and Good Clinical Practice (GCP).
- Experience administering medications and assessing patient responses.
- Strong attention to detail and ability to recognize and respond to adverse events.
- Excellent communication and documentation skills.
- Ability to work independently and collaboratively in a fast-paced clinical research setting.
- Ability and willingness to work overnight shifts.
Employment with ICON is contingent upon having the legal right to work in the country where the role is based.
Rewards & Benefits
ICON offers a competitive and comprehensive total rewards package designed to support your health, wellbeing, and career development.
Benefits May Include
- Competitive base salary and performance related incentives
- Health and wellbeing programmes including medical, dental, and vision coverage where applicable
- Retirement and pension plans
- Life assurance and disability coverage
- Employee assistance programmes and wellbeing resources
- Learning and development opportunities through structured training and career pathways
Benefits may vary depending on role and location.
Visit our careers site to read more about the benefits ICON offers.
Inclusion and Accessibility
ICON is an equal opportunity employer. We are committed to building an inclusive and accessible workplace where everyone feels valued and supported.
If you require reasonable accommodations during the recruitment process, please let us know or submit a request here.
Are you a current ICON Employee? Please click here to apply
Key Responsibilities
The Clinical Research Nurse will administer investigational products and monitor research participants during overnight study procedures. They are responsible for identifying and documenting adverse events while ensuring strict adherence to study protocols and safety standards.
Requirements
Candidates must hold an active Registered Nurse (RN) license and possess an Associate's or Bachelor's degree in Nursing or a related field. Experience in clinical research or a regulated healthcare environment is preferred, along with strong documentation and communication skills.
Qualifications
- Education
- Bachelor degree
Key Skills
Ambulatory Care Nursing — Registered Nurse Career Context
Of the 50 active Ambulatory Care Nursing listings this role was benchmarked against, 38% are remote, 56% have no call, 66% require no weekends.
The cost-of-living index for Kansas is 90.1 (US average = 100; BEA Regional Price Parities (2024)). 61.0% of Kansas clinicians report burnout symptoms in WeekdayDoc's Burnout Index (2026-01 data).
| Measure | This job | Market |
|---|---|---|
| Cost of living | Kansas index 90.1 | US average = 100BEA Regional Price Parities (2024) |
| Ambulatory Care Nursing listings in Kansas | 7 active | 396 nationallylive on WeekdayDoc, Oct 2026 |
| Work setting | on-site | peers: 38% remote · 56% no call · 66% no weekends50 benchmarked listings |
| Ambulatory Care Nursing pay trend | −1.1% vs prior quarter | —through Sep 2026 |
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