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BMC Software
Boston, Massachusetts

Clinical Research Nurse II

Registered NurseFull-Time

Listed compensation

$90k-$130k

The week · per this posting · weekdays assumed

Ask the employer about the work setting, call expectations, weekend coverage and time off.

Posted 53m ago · Verified live

Job Description

Position Summary

The Clinical Research Nurse II (CRN II) will report directly to the Medical Director (MD) of the Cancer Clinical Trials Program and the Administrative Director in Hematology and Medical Oncology. The CRN II is primarily responsible for performing clinical and patient-facing tasks for patients on study.

Will work with providers to identify potentially eligible patients for open clinical trials, and meet with potential research subjects to review consent forms and discuss trial requirements.

Will see patients during required study visits and, partnering with the clinical research coordinator, ensure compliance with study requirements. The Clinical Research Nurse will also provide clinical perspective and information to regulatory coordinators as needed to facilitate trial activation.

As clinically facing research staff, it is expected that the Clinical Research Nurse will spend the majority of their time in clinic seeing active study patients and will be expected to follow and evaluate 4-6 patients per day 4 days/week (16-24 patients per week).

About BMC

At Boston Medical Center (BMC), our diverse staff works together for one goal — to provide exceptional and equitable care to improve the health of the people of Boston. Our bold vision to transform health care is powered by our respect for our patients and our commitment to ensure everyone who comes through our doors has a positive experience.

You’ll find a supportive work environment at BMC, with rich opportunities throughout your career for training, development, and growth and where you’ll have the tools you need to take charge of your own practice environment.

  • Position: Clinical Research Nurse II
  • Department: Cancer Care Admin
  • Schedule: 40 hours per week

Job Responsibilities

Administrative

Assists principal investigator with clinical trial protocol review process and protocol development as appropriate.

Collaborates with the quality assurance of clinical trials in developing protocol specific materials.

Research

Assists with recruitment and registration of patients to clinical trials.

Coordinates scheduling of patient’s laboratory and radiographic assessments, admissions and clinic visits. Monitors test results as appropriate.

Coordinates with clinical research coordinators and collaborates with staff within respective disease groups and with outside organizations in the completion of clinical research trials.

Clinical

Coordinates study enrollment, protocol treatment, and completion of study requirements for patients participating in clinical trials.

Collaborates with Care Coordination for all patient care referrals. Collaborates with primary nurse (infusion, radiation, surgical) in assuring that patient care needs are met.

Provides protocol education to patients and families; adapts interactions based on age-specific, cultural and other needs of the patient.

Completes orders required specimens for analysis and monitors test results, as appropriate. Administers medications as necessary

Documents in charts as appropriate and communicates observations and findings to protocol investigator and attending physicians.

Provides protocol in-service training and serves as a resource to the health care team. Monitors the environment of care with attention to patient safety, and assures compliance with regulatory agency standards.

Maintains clinical practice that is evidence-based and consistent with nursing policies, procedures, licensure/registration requirements, and professional scope and standards.

Fosters an environment that is sensitive to the needs of diverse populations, including but not limited to culture, ethnicity, gender, and age.

Professional Development

Identifies areas for professional growth. Formulates professional goals, objectives and methods for accomplishing these.

  • Pursues active membership of local and national professional organizations.
  • Participates in committees as necessary.
  • Meets all annual evaluation requirements and competencies within the established time period.
  • Collaborates in preparing professional reports, articles, and presentations for colleagues and the public.

The above statements in this job description are intended to depict the general nature and level of work assigned to the employee(s) in this job. The above is not intended to represent an exhaustive list of accountable duties and responsibilities required

Job Requirements

Education

  • Graduate of an accredited nursing program
  • Baccalaureate Degree required

Certificates, Licenses, Registrations Required

  • Licensed to practice professional nursing as a registered nurse (RN) in the Commonwealth of Massachusetts
  • Current basic cardiac life support certification

Experience

3-5 years research or clinical research experience and or oncology nursing experience is required

Knowledge and Skills

Proficient with standard Microsoft programs (i. e. MS Word, Excel, PowerPoint, Outlook) and web browsers. Ability at a basic level to input and analyze data and generate reports, especially in REDCap databases.

Ability to be highly organized, detail-oriented, and timely. Ability to analyze and solve problems in a systematic, logical, and timely manner.

Position requires tact and diplomacy to successfully motivate/educate subjects and staff, and knowledge of research regulations and research compliance requirements, including Protection of Human Subjects.

Must be able to maintain strict protocols of all confidential or sensitive information. Previous experience with grant writing, IRB submissions, data management, study coordination and database development, preferred.

Excellent English communication skills (oral and written). Bilingual or multi-lingual skills (beyond that of English) appropriate to the patient population served is a plus.

Cultural sensitivity and comfort with a wide range of social, racial and ethnic populations. Strong patient communication and patient education skills.

Job Benefits

  • Competitive pay
  • Tuition reimbursement and tuition remission programs
  • Highly subsidized medical, dental, and vision insurance options

Career Advancement/Professional Development: Access a wealth of ongoing training and development opportunities that will not only enhance your skills but also expand your knowledge base especially for individuals pursuing careers in medicine or biomedical research.

Pioneering Research: Engage in groundbreaking research projects that are driving the forefront of biomedical science.

About the Department

BMC’s Cancer Care Center supports patients during all aspects of their care—from diagnosis through treatment and recovery. The Center’s experienced cancer specialists combine their extensive knowledge and expert skills to focus on each patient’s needs. This comprehensive, multi-specialty team approach to diagnosis, treatment, and follow-up ensures that the most up-to-date options and recommendations are offered to patients in a timely and coordinated way.

Other services include cancer support programs, patient navigation, social work, nutrition, and genetic counseling.

Boston Medical Center is an Equal Opportunity/Affirmative Action Employer. If you need accommodation for any part of the application process because of a medical condition or disability, please send an e-mail to Talentacquisition@bmc.org or call 617-638-8582 to let us know the nature of your request.

Compensation Range

$89,500.00- $130,000.00

This range offers an estimate based on the minimum job qualifications. However, our approach to determining base pay is comprehensive, and a broad range of factors is considered when making an offer.

This includes education, experience, skills, and certifications/licensures as they directly relate to position requirements; as well as business/organizational needs, internal equity, and market-competitiveness.

In addition, BMCHS offers generous total compensation that includes, but is not limited to, benefits (medical, dental, vision, pharmacy), discretionary annual bonuses and merit increases, Flexible Spending Accounts, 403(b) savings matches, paid time off, career advancement opportunities, and resources to support employee and family well-being.

NOTE: This range is based on Boston-area data, and is subject to modification based on geographic location.

Equal Opportunity Employer/Disabled/Veterans

According to the FTC, there has been a rise in employment offer scams. Our current job openings are listed on our website and applications are received only through our website. We do not ask or require downloads of any applications, or “apps” job offers are not extended over text messages or social media platforms. We do not ask individuals to purchase equipment for or prior to employment.

Key Responsibilities

The Clinical Research Nurse II is responsible for performing clinical and patient-facing tasks for patients enrolled in cancer clinical trials. This includes identifying eligible patients, obtaining informed consent, coordinating study visits, and ensuring strict adherence to research protocols.

Requirements

Candidates must be graduates of an accredited nursing program with a Baccalaureate degree and hold a current Massachusetts RN license. A minimum of 3-5 years of research or oncology nursing experience is required.

Qualifications

Education
Bachelor degree
Experience
2+ years of experience

Key Skills

Protocol compliancePatient recruitmentRegulatory complianceClinical trial coordinationMicrosoft OfficeEvidence-based practiceProblem-solving

Ambulatory Care Nursing — Registered Nurse Career Context

Of the 50 active Ambulatory Care Nursing listings this role was benchmarked against, 18% are remote, 50% have no call, 70% require no weekends.

In Massachusetts, the Ambulatory Care Nursing weighted monthly median benchmark on WeekdayDoc is ~$128k (14 salary observations; 23 listings), vs ~$96k nationally (409 salary observations; 1,283 listings). Monthly aggregates cover 2026-01-01 through 2026-10-01; these are not the modal's selected comparable-job medians.

The cost-of-living index for Massachusetts is 105.8 (US average = 100; BEA Regional Price Parities (2024)), so the posted ~$110k midpoint carries the purchasing power of roughly $104k in an average-cost state. 63.2% of Massachusetts clinicians report burnout symptoms in WeekdayDoc's Burnout Index (2026-01 data).

BMC Software ranks #3 of 14 employers hiring Registered Nurse on WeekdayDoc by average advertised pay.

Ambulatory Care Nursing pay on WeekdayDoc is down 1.1% vs. the prior quarter (through Sep 2026).

Work-Life Balance Analysis

WeekdayDoc's proprietary algorithm rates Clinical Research Nurse II at BMC Software a 6.0 out of 10 for work-life balance — classified as good. This places the position in the Above average in Ambulatory Care Nursing (RN) — ranked against 382 active Ambulatory Care Nursing (RN) listings on WeekdayDoc.

Top Registered Nurse Jobs

32 matches · ranked by pay

Salary Distribution32 jobs · 26 employers

11
<$105k
10
$105k-125k
7
$125k-145k
3
$145k-165k
1
$165k

Annual compensation range

Benefits & Perks26 jobs

401k / retirement match
88% this job
Sign-on bonus
27%
CME allowance
15%
Loan repayment
4%

Share of similar jobs offering each benefit

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$144k-$165k
#2

Oncology/Palliative Nurse Educator MRMC - Med/Surg/Oncology - 24 hr Mixed

UMass Memorial Health · Milford, Massachusetts

$91k-$164k
#3

Asst. Director of Nursing - Ambulatory Care - Newkirk Avenue

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#4

Director of Nursing

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+ 30 more · ranked by pay

Work-life snapshot

median 5.1this job 6.0
Better work-life than 70% of Ambulatory Care Nursing (RN) listings

Listing-based score, 0–10, across 382 comparable listings. Shaded area = the share scoring below this one.

Living in Boston

Typical 3-bedroom home value
$813k≈ 9.1× annual pay
Typical market rent
$3,338/mo≈ 45% of gross pay
Residents’ average commute
30 min
Metro price indexU.S. average = 100
108.3
State income tax
Up to 5%
Sources & methodology

Sources: Zillow home values (Aug 2026), Zillow market rents (Aug 2026), U.S. Census ACS 2024 five-year.

BEA 2024 · Boston-Cambridge-Newton, MA-NH metro prices. Housing figures are city-level.

Ratios use this listing’s gross annual pay. Not a cost-of-living guarantee.

BMC Software logo

About BMC Software

Medical Practices
Arlington, Massachusetts
51-200 employees

Benefits & Perks

Competitive pay
Tuition reimbursement and remission
Highly subsidized medical, dental, and vision insurance
403(b) savings match
Paid time off
Career advancement opportunities