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Astra Zeneca
Gaithersburg, Maryland · Hybrid

Global Development Medical Director, Late Respiratory and Immunology Clinical Development

Medical AffairsFull-Time

Listed compensation

$242k-$362k

The week · per this posting · weekdays assumed

Ask the employer about call expectations, weekend coverage, nights and shift pattern and time off.

Posted 1mo ago

Job Description

Global Development Medical Director, Late Respiratory and Immunology Clinical Development

As a Global Development Medical Director, you will support the clinical project team and assist the Global Clinical Project Leader and Global Clinical Head with the design & interpretation process, establishing clear design objectives for clinical programs and studies.

You will provide medical input into the content of core labelling texts and medical support for commercial activities, support for medical monitoring of clinical studies.

And, you will also provide medical and scientific expertise as well as tactical and strategic medical input to the development of AstraZeneca’s compounds; primarily from Phase IIb to Phase IV.

This includes the design, delivery and interpretation of pivotal clinical trials and of studies that further characterize the overall benefit and risk and value of Respiratory and Immunology products in late-stage development.

In the BioPharmaceuticals Research & Development, Late-stage Development, Respiratory & Immunology function you will work in a truly international working environment, with opportunities to meet and discuss with key external experts, other medical colleagues and experts in basic science, as well as commercial and regulatory functions.

Our therapy area aligned groups of physicians and scientists provide clinical guidance and scientific leadership for clinical development programs within AstraZeneca's global organization.

The Global Development Medical Director will work in a wide range of aspects in pharmaceutical medicine, and due to the global responsibilities, there will be a multitude of contacts with health authorities, colleagues and marketing companies within AstraZeneca. This is an opportunity to take on the challenges of clinical development in a group of positive, focused and highly motivated colleagues.

What You Will Do

Be involved in providing medical and scientific leadership in the global development of new medicines targeted at indications in the field of respiratory diseases and wider range of immunological disorders

Have an important role providing medical and scientific leadership in the innovative design, execution and interpretation of clinical trials in one or more development programs.

Build strong relationships with a network of external scientific experts.

Work closely with colleagues in other functions including Patient Safety, Regulatory Affairs, and Clinical Operations.

Be involved primarily in late stage (Ph2b and later) clinical programs while also collaborating with clinical colleagues supporting Early (R&I) stage programs and medical affairs.

Lead and contribute to medical monitoring of trials

Provide expert medical input into the preparation of regulatory documents and interactions with regulatory authorities.

Provide expert medical and scientific analysis and interpretation of data from ongoing studies and in the literature.

Develop and review protocols, informed consent, investigator’s brochure and other clinical development documents.

Participate in the preparation of scientific publications and presentations at scientific meetings and congresses.

Basic Qualifications

MD or MD/PhD

3+ years of pharmaceutical industry experience OR 3+ years of clinical research experience in the academic or clinical practice setting

Demonstrated partnership and collaboration skills, including acting as the leader and clearly communicating across countries and cultures

Fluent in oral and written English, with good presentation skills and effective communication

Desired Qualifications

Pulmonary medicine, Immunology, or Allergy, background is desirable.

The annual base pay for this position ranges from $241,613 – $362,420 USD. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience.

In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program.

Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans.

Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment.

If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility.

Join us in our unique and bold world.

21-Sep-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

Key Responsibilities

The Global Development Medical Director provides medical and scientific leadership for late-stage clinical development programs in respiratory and immunology. Responsibilities include designing clinical trials, monitoring study progress, and ensuring regulatory compliance through expert analysis and documentation.

Requirements

Candidates must hold an MD or MD/PhD degree with at least 3 years of experience in the pharmaceutical industry or clinical research. Strong communication, leadership, and collaboration skills are required, with a background in pulmonary medicine, immunology, or allergy being highly desirable.

Qualifications

Education
Doctoral or professional degree (postgraduate degree)
Experience
2+ years of experience

Key Skills

Clinical trial designData interpretationRespiratory medicineRegulatory documentationMedical writingProject managementCross-functional collaboration

Medical Affairs — Physician Career Context

The cost-of-living index for Maryland is 105.0 (US average = 100; BEA Regional Price Parities (2024)), so the posted ~$302k midpoint carries the purchasing power of roughly $288k in an average-cost state. 62.9% of Maryland clinicians report burnout symptoms in WeekdayDoc's Burnout Index (2026-01 data).

Astra Zeneca holds silver-tier status on WeekdayDoc's Top Employers work-life index, composite score 74/100, 26 active listings.

What does the Medical Affairs market look like in Maryland?
MeasureThis jobMarket
Work-life score6.0 / 10 · top 25% in medical affairsranked against 273 Medical Affairs listingslisting-based score, 0–10
Listed pay$242k–$362kMedical Affairs median $293k (middle half $264k–$324k)56 comparable listings, Nov 2026
Cost-of-living adjusted pay~$288k in purchasing powerMaryland index 105.0 (US = 100)BEA Regional Price Parities (2024)
Medical Affairs listings in Maryland11 active273 nationallylive on WeekdayDoc, Nov 2026
Sign-on & loan repaymentsign-on bonusMaryland physician listings (all specialties): 22% state a sign-on bonus (median $50k) · 10% offer loan repayment412 active listings, Nov 2026
Medical Affairs hiring demand#6 of 28 specialtiespostings stay open a median 69 daysWeekdayDoc Hiring Index, October 2026 · 162 postings, 36 closed
New Medical Affairs listings94 in the last 30 days90 the 30 days before (+4%)U.S., first seen on WeekdayDoc, Nov 2026
Medical Affairs pay trend+2.9% vs prior quarter—through Oct 2026
Astra Zenecasilver tier, 74/100Top Employers work-life index26 active listings
Sources: WeekdayDoc live listing index (273 Medical Affairs listings), Top Employers work-life index, BEA Regional Price Parities (2024), WeekdayDoc Hiring Index; as of Nov 2026. Same values as the Weekday Verdict and Market Insights on this page.

Work-Life Balance Analysis

WeekdayDoc's proprietary algorithm rates Global Development Medical Director, Late Respiratory and Immunology Clinical Development at Astra Zeneca a 6.0 out of 10 for work-life balance — classified as good. This places the position in the top 25% in Medical Affairs — ranked against 273 active Medical Affairs listings on WeekdayDoc. Contributing factors include remote work flexibility.

Top Medical Affairs Jobs

1 matches · ranked by pay
#1

Payer & Health Systems Oncology, Medical Affairs Director (PHSO MAD) (PA, MD, Upstate NY)

MSD · Baltimore, Maryland

$210k-$331k

Work-life snapshot

median 3.0this job 6.0
Better work-life than 80% of Medical Affairs listings

Listing-based score, 0–10, across 273 comparable listings. Shaded area = the share scoring below this one.

  • Hybrid
  • Remote
Astra Zeneca logo

About Astra Zeneca

Pharmaceutical Manufacturing
Cambridge, Cambridgeshire
10,000+ employees

Benefits & Perks

Short-Term Incentive Bonus
Equity-Based Long-Term Incentive Program
401(k) Plan
Paid Vacation and Holidays
Paid Leaves
Health Benefits (Medical, Prescription Drug, Dental, Vision)
Hybrid Work (Minimum 3 Days/Week in Office)